General Information of the Compound
| Compound ID |
CP0866110
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| Compound Name |
N-(2,6-difluorophenyl)-5-[3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}-7-(methyloxy)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
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| Structure |
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| Formula |
C36H33F2N7O4
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| Molecular Weight |
665.701
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| Canonical SMILES |
COc1ccn2c(-c3ccnc(Nc4cccc(OCCN(C)C)c4)n3)c(-c3ccc(OC)c(C(=O)Nc4c(F)cccc4F)c3)nc2c1
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| InChI |
InChI=1S/C36H33F2N7O4/c1-44(2)17-18-49-25-8-5-7-23(20-25)40-36-39-15-13-29(41-36)34-32(42-31-21-24(47-3)14-16-45(31)34)22-11-12-30(48-4)26(19-22)35(46)43-33-27(37)9-6-10-28(33)38/h5-16,19-21H,17-18H2,1-4H3,(H,43,46)(H,39,40,41)
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| InChIKey |
JHAJPTOYCXHOLN-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor