Brief Information of the Compound and Protein
Compound Name
7-cyclobutyl-5-(2-phenylquinolin-7-yl)imidazo[1,5-f][1,2,4]triazin-4-amine
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PubChem ID
CID: 11502053
SID: 16604010
Canonical SMILES
Nc1ncnn2c(nc(-c3ccc4ccc(nc4c3)-c3ccccc3)c12)C1CCC1
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Compound Formula C24H20N6
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 270 nM