General Information of the Compound
| Compound ID |
CP0888393
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| Compound Name |
5-(3-(2-(4-(1,4'-bipiperidin-1'-yl)-2-methoxyphenylamino)pyrimidin-4-yl)-7-methylimidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)-2-methoxybenzamide
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| Structure |
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| Formula |
C43H44F2N8O3
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| Molecular Weight |
758.874
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| Canonical SMILES |
COc1cc(N2CCC(N3CCCCC3)CC2)ccc1Nc1nccc(-c2c(-c3ccc(OC)c(C(=O)Nc4c(F)cccc4F)c3)nc3cc(C)ccn23)n1
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| InChI |
InChI=1S/C43H44F2N8O3/c1-27-15-23-53-38(24-27)49-39(28-10-13-36(55-2)31(25-28)42(54)50-40-32(44)8-7-9-33(40)45)41(53)35-14-18-46-43(48-35)47-34-12-11-30(26-37(34)56-3)52-21-16-29(17-22-52)51-19-5-4-6-20-51/h7-15,18,23-26,29H,4-6,16-17,19-22H2,1-3H3,(H,50,54)(H,46,47,48)
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| InChIKey |
HUTQKWNUUVHNAV-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor