General Information of the Compound
| Compound ID |
CP0946200
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| Compound Name |
N-(2,6-difluorophenyl)-5-[3-(2-{[5-methyl-2-(methyloxy)-4-(1-propyl-4-piperidinyl)phenyl]-amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
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| Structure |
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| Formula |
C41H41F2N7O3
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| Molecular Weight |
717.821
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| Canonical SMILES |
CCCN1CCC(c2cc(OC)c(Nc3nccc(-c4c(-c5ccc(OC)c(C(=O)Nc6c(F)cccc6F)c5)nc5ccccn45)n3)cc2C)CC1
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| InChI |
InChI=1S/C41H41F2N7O3/c1-5-18-49-20-15-26(16-21-49)28-24-35(53-4)33(22-25(28)2)46-41-44-17-14-32(45-41)39-37(47-36-11-6-7-19-50(36)39)27-12-13-34(52-3)29(23-27)40(51)48-38-30(42)9-8-10-31(38)43/h6-14,17,19,22-24,26H,5,15-16,18,20-21H2,1-4H3,(H,48,51)(H,44,45,46)
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| InChIKey |
YXAQENFRPVZZLS-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor