Brief Information of the Compound and Protein
Compound Name
N-(2,6-difluorophenyl)-5-{3-[2-({2-methyl-3-[(4-methyl-1-piperazinyl)methyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-2-(methyloxy)benzamide
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PubChem ID
CID: 59452739
Canonical SMILES
COc1ccc(-c2nc3ccccn3c2-c2ccnc(Nc3cccc(CN4CCN(C)CC4)c3C)n2)cc1C(=O)Nc1c(F)cccc1F
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Compound Formula C38H36F2N8O2
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 < 100 nM
   TI
   LI
   LO
   TS