General Information of the Compound
| Compound ID |
CP0895690
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| Compound Name |
N-(2,6-difluorophenyl)-3-[3-(2-{[2-(methyloxy)-4-(4-propyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
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| Structure |
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| Formula |
C38H36F2N8O2
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| Molecular Weight |
674.756
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| Canonical SMILES |
CCCN1CCN(c2ccc(Nc3nccc(-c4c(-c5cccc(C(=O)Nc6c(F)cccc6F)c5)nc5ccccn45)n3)c(OC)c2)CC1
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| InChI |
InChI=1S/C38H36F2N8O2/c1-3-17-46-19-21-47(22-20-46)27-13-14-30(32(24-27)50-2)42-38-41-16-15-31(43-38)36-34(44-33-12-4-5-18-48(33)36)25-8-6-9-26(23-25)37(49)45-35-28(39)10-7-11-29(35)40/h4-16,18,23-24H,3,17,19-22H2,1-2H3,(H,45,49)(H,41,42,43)
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| InChIKey |
LWNYZEYOSPILOO-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor