General Information of the Compound
| Compound ID |
CP0882931
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| Compound Name |
N-(2,6-difluorophenyl)-5-[3-(2-{[2-(ethyloxy)-4-(1-propyl-4-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
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| Structure |
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| Formula |
C41H41F2N7O3
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| Molecular Weight |
717.821
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| Canonical SMILES |
CCCN1CCC(c2ccc(Nc3nccc(-c4c(-c5ccc(OC)c(C(=O)Nc6c(F)cccc6F)c5)nc5ccccn45)n3)c(OCC)c2)CC1
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| InChI |
InChI=1S/C41H41F2N7O3/c1-4-20-49-22-17-26(18-23-49)27-12-14-32(35(25-27)53-5-2)45-41-44-19-16-33(46-41)39-37(47-36-11-6-7-21-50(36)39)28-13-15-34(52-3)29(24-28)40(51)48-38-30(42)9-8-10-31(38)43/h6-16,19,21,24-26H,4-5,17-18,20,22-23H2,1-3H3,(H,48,51)(H,44,45,46)
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| InChIKey |
ZVVUDOXQGMMBCV-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor