General Information of the Compound
| Compound ID |
CP0857319
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| Compound Name |
N-(2,6-difluorophenyl)-5-{3-[2-({2-(ethyloxy)-4-[2-(4-methyl-1-piperazinyl)ethyl]-phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-2-(methyloxy)benzamide
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| Structure |
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| Formula |
C38H36F2N8O3
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| Molecular Weight |
690.755
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| Canonical SMILES |
CCOc1cc(N2CCN(C)CC2)ccc1Nc1nccc(-c2c(-c3ccc(OC)c(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1
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| InChI |
InChI=1S/C38H36F2N8O3/c1-4-51-32-23-25(47-20-18-46(2)19-21-47)12-13-29(32)42-38-41-16-15-30(43-38)36-34(44-33-10-5-6-17-48(33)36)24-11-14-31(50-3)26(22-24)37(49)45-35-27(39)8-7-9-28(35)40/h5-17,22-23H,4,18-21H2,1-3H3,(H,45,49)(H,41,42,43)
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| InChIKey |
QHIGHCKBCQWHDJ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor