General Information of the Compound
| Compound ID |
CP0882930
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| Compound Name |
N-(2,6-difluorophenyl)-2-(methyloxy)-5-[3-(2-{[2-(methyloxy)-4-(1-propyl-4-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
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| Structure |
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| Formula |
C40H39F2N7O3
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| Molecular Weight |
703.794
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| Canonical SMILES |
CCCN1CCC(c2ccc(Nc3nccc(-c4c(-c5ccc(OC)c(C(=O)Nc6c(F)cccc6F)c5)nc5ccccn45)n3)c(OC)c2)CC1
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| InChI |
InChI=1S/C40H39F2N7O3/c1-4-19-48-21-16-25(17-22-48)26-11-13-31(34(24-26)52-3)44-40-43-18-15-32(45-40)38-36(46-35-10-5-6-20-49(35)38)27-12-14-33(51-2)28(23-27)39(50)47-37-29(41)8-7-9-30(37)42/h5-15,18,20,23-25H,4,16-17,19,21-22H2,1-3H3,(H,47,50)(H,43,44,45)
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| InChIKey |
HVTCTUCTHJXITI-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor