| Compound ID |
Compound Name |
Compound Formula |
|
CP0867031
|
Trans-4,4-dimethyl-2-(4-(3-(piperidin-1-yl)cyclobutoxy)phenyl)-4,5-dihydrooxazole
Show/Hide
|
C20H28N2O2
|
2
|
| 1 |
EC50 = 0.631 nM
|
|
|
| 2 |
Ki = 7.943 nM
|
|
|
|
CP0110239
|
4-(1H-imidazol-4-ylmethyl)piperidine
Show/Hide
|
C9H15N3
|
3
|
| 1 |
EC50 = 0.67 nM
|
|
|
| 2 |
Ki = 0.3 nM
|
|
|
| 3 |
Ki = 0.4074 nM
|
|
|
|
CP0167907
|
1-methyl-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C20H26N2O2
|
2
|
| 1 |
EC50 = 0.7 nM
|
|
|
| 2 |
Ki = 0.7 nM
|
|
|
|
CP0070912
|
3,5-dimethyl-N-[2-methyl-4-[(3S)-3-[(2S)-2-methylpyrrolidin-1-yl]pyrrolidin-1-yl]phenyl]-1,2-oxazole-4-carboxamide
Show/Hide
|
C22H30N4O2
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0092861
|
2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole
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|
C15H20N2S
|
3
|
| 1 |
EC50 = 0.75 nM
|
|
|
| 2 |
Ki = 0.17 nM
|
|
|
| 3 |
Ki = 0.43 nM
|
|
|
|
CP0107784
|
N-[2-methyl-4-[(3S)-3-[(2S)-2-methylpyrrolidin-1-yl]pyrrolidin-1-yl]phenyl]oxane-4-carboxamide
Show/Hide
|
C22H33N3O2
|
2
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0417488
|
(5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C21H29N3O3
|
2
|
| 1 |
EC50 < 1 nM
|
|
|
| 2 |
Ki = 5 nM
|
|
|
|
CP0417489
|
(3-hydroxypyrrolidin-1-yl)(5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)methanone
Show/Hide
|
C21H29N3O3
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0496514
|
azepan-1-yl-[5-(1-propan-2-ylpiperidin-4-yl)oxy-1H-indol-2-yl]methanone
Show/Hide
|
C23H33N3O2
|
2
|
| 1 |
EC50 < 1 nM
|
|
|
| 2 |
Ki = 6 nM
|
|
|
|
CP0376332
|
4-(1H-imidazol-5-ylmethyl)pyridine
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|
C9H9N3
|
3
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
Ki = 0.77 nM
|
|
|
| 3 |
Ki = 0.7943 nM
|
|
|
|
CP0907283
|
2-(4-(3-(piperidin-1-yl)propoxy)phenyl)-4-(piperidin-1-ylmethyl)oxazole
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|
C23H33N3O2
|
2
|
| 1 |
EC50 = 1.585 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0917737
|
Methyl trans-4-methyl-2-(4-(3-(piperidin-1-yl)cyclobutoxy)phenyl)oxazole-5-carboxylate
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|
C21H26N2O4
|
2
|
| 1 |
EC50 = 1.585 nM
|
|
|
| 2 |
Ki = 1.995 nM
|
|
|
|
CP0406666
|
4-(2-(4-tert-Butylphenylamino)ethyl)-1H-imidazole
Show/Hide
|
C15H21N3
|
2
|
| 1 |
EC50 = 1.6 nM
|
|
|
| 2 |
Ki = 0.89 nM
|
|
|
|
CP0866640
|
Trans-2-(4-(3-(piperidin-1-yl)cyclobutoxy)phenyl)-3-oxa-1-azaspiro[4.5]dec-1-ene
Show/Hide
|
C23H32N2O2
|
2
|
| 1 |
EC50 = 1.995 nM
|
|
|
| 2 |
Ki = 1.995 nM
|
|
|
|
CP0453807
|
2-(2-(4,4-difluoropiperidine-1-carbonyl)-5-(1-isopropylpiperidin-4-yloxy)-1H-indol-1-yl)acetonitrile
Show/Hide
|
C24H30F2N4O2
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
|
CP0471954
|
(1-(3,4-dichlorophenyl)-5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(4,4-difluoropiperidin-1-yl)methanone
Show/Hide
|
C28H31Cl2F2N3O2
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0471955
|
(5-(1-cyclopropylpiperidin-4-yloxy)-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C23H28F3N3O3
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0502196
|
(5-(1-cyclobutylpiperidin-4-yloxy)-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C24H30F3N3O3
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0105108
|
2-methyl-6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]pyridazin-3-one
Show/Hide
|
C18H23N3O
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0091564
|
2-(4-fluorophenyl)-6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]pyridazin-3-one
Show/Hide
|
C23H24FN3O
|
2
|
| 1 |
EC50 = 2.1 nM
|
|
|
| 2 |
Ki = 13 nM
|
|
|
|
CP0098027
|
2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide
Show/Hide
|
C6H10N4S
|
2
|
| 1 |
EC50 = 2.4 nM
|
|
|
| 2 |
Ki = 0.57 nM
|
|
|
|
CP0047136
|
(2R)-1-(1H-imidazol-5-yl)propan-2-amine
Show/Hide
|
C6H11N3
|
4
|
| 1 |
EC50 = 2.8 nM
|
|
|
| 2 |
Ki = 0.55 nM
|
|
|
| 3 |
Ki = 1.995 nM
|
|
|
| 4 |
Ki = 2.7 nM
|
|
|
|
CP0387957
|
(3,3-difluoropiperidin-1-yl)(5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)methanone
Show/Hide
|
C22H29F2N3O2
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0387958
|
(4-cyclobutylpiperazin-1-yl)(2-(morpholine-4-carbonyl)-1-(2,2,2-trifluoroethyl)-1H-indol-5-yl)methanone
Show/Hide
|
C24H29F3N4O3
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0900429
|
Trans-2-(4-(3-(piperidin-1-yl)cyclobutoxy)phenyl)-4-(piperidin-1-ylmethyl)oxazole
Show/Hide
|
C24H33N3O2
|
2
|
| 1 |
EC50 = 3.162 nM
|
|
|
| 2 |
Ki = 1.259 nM
|
|
|
|
CP0417486
|
(5-(1-cyclopropylpiperidin-4-yloxy)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C21H27N3O3
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0417499
|
(4,4-difluoropiperidin-1-yl)(5-(1-isopropylpiperidin-4-yloxy)-1-(methylsulfonyl)-1H-indol-2-yl)methanone
Show/Hide
|
C23H31F2N3O4S
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
|
CP0453808
|
(5-(1-isopropylpiperidin-4-yloxy)-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C23H30F3N3O3
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
|
CP0453809
|
(1,1-Dioxo-1lambda*6*-thiomorpholin-4-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1-(2,2,2-trifluoro-ethyl)-1H-indol-2-yl]-methanone
Show/Hide
|
C23H30F3N3O4S
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
Ki = 11 nM
|
|
|
|
CP0491081
|
(4,4-Difluoropiperidin-1-yl)[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]methanone
Show/Hide
|
C22H29F2N3O2
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0506037
|
(4,4-difluoropiperidin-1-yl)(5-(1-isopropylpiperidin-4-yloxy)-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl)methanone
Show/Hide
|
C24H30F5N3O2
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
|
CP0501795
|
4-(2-(3-tert-Butylphenylamino)ethyl)-1H-imidazole
Show/Hide
|
C15H21N3
|
2
|
| 1 |
EC50 = 4.6 nM
|
|
|
| 2 |
Ki = 2.2 nM
|
|
|
|
CP0246942
|
(4,4-Difluoropiperidin-1-yl)[1-isopropyl-5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl]methanone
Show/Hide
|
C25H35F2N3O2
|
2
|
| 1 |
EC50 = 5 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0491039
|
2-(ethoxycarbonyl)-1H-indole-5-carboxylic acid
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|
C12H11NO4
|
2
|
| 1 |
EC50 = 5 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0437596
|
(5-(1-tert-butylpiperidin-4-yloxy)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C22H31N3O3
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
|
CP0505537
|
(1,1-Dioxo-1lambda*6*-thiomorpholin-4-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-methanone
Show/Hide
|
C21H29N3O4S
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0494446
|
1-(2-(4,4-difluoropiperidine-1-carbonyl)-5-(1-isopropylpiperidin-4-yloxy)-1H-indol-1-yl)ethanone
Show/Hide
|
C24H31F2N3O3
|
2
|
| 1 |
EC50 = 7 nM
|
|
|
| 2 |
Ki = 13 nM
|
|
|
|
CP0866637
|
2-(4-(3-(piperidin-1-yl)propoxy)phenyl)-3-oxa-1-azaspiro[4.5]dec-1-ene
Show/Hide
|
C22H32N2O2
|
2
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0491083
|
morpholin-4-yl-[5-[1-(oxetan-3-yl)piperidin-4-yl]oxy-1-(2,2,2-trifluoroethyl)indol-2-yl]methanone
Show/Hide
|
C23H28F3N3O4
|
2
|
| 1 |
EC50 = 9 nM
|
|
|
| 2 |
Ki = 23 nM
|
|
|
|
CP0494438
|
(5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(4-methoxypiperidin-1-yl)methanone
Show/Hide
|
C23H33N3O3
|
2
|
| 1 |
EC50 = 9 nM
|
|
|
| 2 |
Ki = 9 nM
|
|
|
|
CP0417992
|
(4,4-difluoropiperidin-1-yl)(1-(4-fluorophenylsulfonyl)-5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)methanone
Show/Hide
|
C28H32F3N3O4S
|
2
|
| 1 |
EC50 = 11 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0125261
|
2-(2-(4-tert-Butylphenylthio)-1-(1H-imidazol-4-yl)ethyl)pyridine
Show/Hide
|
C20H23N3S
|
2
|
| 1 |
EC50 = 15 nM
|
|
|
| 2 |
Ki = 16 nM
|
|
|
|
CP0956767
|
4,4-dimethyl-2-(4-(3-(piperidin-1-yl)propoxy)phenyl)-4,5-dihydrooxazole
Show/Hide
|
C19H28N2O2
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 158.49 nM
|
|
|
|
CP0127531
|
(6-(1-isopropylpiperidin-4-yloxy)naphthalen-2-yl)(morpholino)methanone
Show/Hide
|
C23H30N2O3
|
2
|
| 1 |
EC50 = 17 nM
|
|
|
| 2 |
Ki = 40 nM
|
|
|
|
CP0411149
|
4-(2-(4-Trifluoromethylphenylamino)ethyl)-1H-imidazole
Show/Hide
|
C12H11F3N2S
|
2
|
| 1 |
EC50 = 19 nM
|
|
|
| 2 |
Ki = 1.1 nM
|
|
|
|
CP0071708
|
N-cyclohexyl-6-(1-propan-2-ylpiperidin-4-yl)oxynaphthalene-2-carboxamide
Show/Hide
|
C25H34N2O2
|
2
|
| 1 |
EC50 = 21 nM
|
|
|
| 2 |
Ki = 87 nM
|
|
|
|
CP0105462
|
3-(2-(4-tert-Butylphenylthio)-1-(1H-imidazol-4-yl)ethyl)pyridine
Show/Hide
|
C20H23N3S
|
2
|
| 1 |
EC50 = 22 nM
|
|
|
| 2 |
Ki = 64 nM
|
|
|
|
CP0417498
|
(6-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C21H29N3O3
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
Ki = 33 nM
|
|
|
|
CP0125262
|
(S)-4-(1-(1H-Imidazol-4-yl)-2-(4-(trifluoromethyl)phenylthio)-ethyl)piperidine
Show/Hide
|
C17H20F3N3S
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
|
CP0476321
|
4-(2-(3,4-Dimethylphenylamino)ethyl)-1H-imidazole
Show/Hide
|
C13H17N3
|
2
|
| 1 |
EC50 = 25 nM
|
|
|
| 2 |
Ki = 9.9 nM
|
|
|
|
CP0683099
|
4-(1-(1H-Imidazol-4-yl)-2-(4-(trifluoromethyl)phenylthio)ethyl)-piperidine
Show/Hide
|
C17H20F3N3S
|
2
|
| 1 |
EC50 = 38 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0372971
|
(5-(1-isopropylpiperidin-4-ylamino)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C21H30N4O2
|
2
|
| 1 |
EC50 = 44 nM
|
|
|
| 2 |
Ki = 64 nM
|
|
|
|
CP0470820
|
2-(1-(1H-Imidazole-4-yl)-2-(4-trifluoromeethylphenylthio)-ethyl)pyridine
Show/Hide
|
C17H14F3N3S
|
2
|
| 1 |
EC50 = 48 nM
|
|
|
| 2 |
Ki = 75 nM
|
|
|
|
CP0453817
|
morpholin-4-yl-[5-(3-piperidin-1-ylpropoxy)-1H-indol-2-yl]methanone
Show/Hide
|
C21H29N3O3
|
2
|
| 1 |
EC50 = 54 nM
|
|
|
| 2 |
Ki = 71 nM
|
|
|
|
CP0405967
|
4-(2-(4-Methoxyphenylamino)ethyl)-1H-imidazole
Show/Hide
|
C12H14N2OS
|
2
|
| 1 |
EC50 = 65 nM
|
|
|
| 2 |
Ki = 24 nM
|
|
|
|
CP0470821
|
3-(1-(1H-Imidazole-4-yl)-2-(4-trifluoromeethylphenylthio)ethyl)-pyridine
Show/Hide
|
C17H14F3N3S
|
2
|
| 1 |
EC50 = 67 nM
|
|
|
| 2 |
Ki = 120 nM
|
|
|
|
CP0105464
|
(R)-4-(1-(1H-Imidazol-4-yl)-2-(4-(trifluoromethyl)phenylthio)ethyl)piperidine
Show/Hide
|
C17H20F3N3S
|
2
|
| 1 |
EC50 = 74 nM
|
|
|
| 2 |
Ki = 180 nM
|
|
|
|
CP0867032
|
Cis-2-(4-(3-(piperidin-1-yl)cyclobutoxy)phenyl)-3-oxa-1-azaspiro[4.5]dec-1-ene
Show/Hide
|
C23H32N2O2
|
2
|
| 1 |
EC50 = 79.43 nM
|
|
|
| 2 |
Ki = 251.19 nM
|
|
|
|
CP0467372
|
4-(2-(4-Methylphenylamino)ethyl)-1H-imidazole
Show/Hide
|
C12H15N3
|
2
|
| 1 |
EC50 = 88 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
|
CP0044460
|
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
Show/Hide
|
C15H24N4S
|
4
|
| 1 |
EC50 = 100 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
| 3 |
Ki = 60 nM
|
|
|
| 4 |
Ki = 158.49 nM
|
|
|
|
CP0387959
|
(5-fluoro-6-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(morpholino)methanone
Show/Hide
|
C21H28FN3O3
|
2
|
| 1 |
EC50 = 112 nM
|
|
|
| 2 |
Ki = 366 nM
|
|
|
|
CP0228482
|
4-(1-(1H-Imidazole-4-yl)-2-(4-trifluoromeethylphenylthio)ethyl)-pyridine
Show/Hide
|
C17H14F3N3S
|
2
|
| 1 |
EC50 = 140 nM
|
|
|
| 2 |
Ki = 200 nM
|
|
|
|
CP0380345
|
3-((1H-imidazol-4-yl)methyl)pyridine
Show/Hide
|
C9H9N3
|
2
|
| 1 |
EC50 = 140 nM
|
|
|
| 2 |
Ki = 76 nM
|
|
|
|
CP0470819
|
4-(2-(4-tert-Butylphenylthio)-1-(1H-imidazol-4-yl)ethyl)pyridine
Show/Hide
|
C20H23N3S
|
2
|
| 1 |
EC50 = 140 nM
|
|
|
| 2 |
Ki = 130 nM
|
|
|
|
CP0136436
|
(4-methylpiperidin-1-yl)(6-(3-(piperidin-1-yl)propoxy)naphthalen-2-yl)methanone
Show/Hide
|
C25H34N2O2
|
2
|
| 1 |
EC50 = 200 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0406667
|
4-(2-(Phenylamino)ethyl)-1H-imidazole
Show/Hide
|
C11H13N3
|
2
|
| 1 |
EC50 = 320 nM
|
|
|
| 2 |
Ki = 56 nM
|
|
|
|
CP0505535
|
(5-(1-isopropylpiperidin-4-yloxy)-2-methyl-1H-indol-3-yl)(morpholino)methanone
Show/Hide
|
C22H31N3O3
|
2
|
| 1 |
EC50 = 405 nM
|
|
|
| 2 |
Ki = 86 nM
|
|
|
|
CP0289437
|
4-(2-(4-tert-Butylphenylthio)-1-(1H-imidazol-4-yl)ethyl)piperidine
Show/Hide
|
C20H29N3S
|
2
|
| 1 |
EC50 = 540 nM
|
|
|
| 2 |
Ki = 530 nM
|
|
|
|
CP0036920
|
2-(1H-imidazol-4-yl)ethan-1-amine
Show/Hide
|
C5H9N3
|
2
|
| 1 |
EC50 = 640 nM
|
|
|
| 2 |
Ki = 5.2 nM
|
|
|
|
CP0441099
|
2-((1H-imidazol-4-yl)methyl)pyridine
Show/Hide
|
C9H9N3
|
2
|
| 1 |
EC50 = 1300 nM
|
|
|
| 2 |
Ki = 1800 nM
|
|
|
|
CP0406785
|
4-(2-(Cyclohexylamino)ethyl)-1H-imidazole
Show/Hide
|
C11H19N3
|
2
|
| 1 |
EC50 = 3400 nM
|
|
|
| 2 |
Ki = 1600 nM
|
|
|
|
CP0406092
|
3-(4-tert-Butylphenylthio)-2-(1H-imidazol-4-yl)-N-methylpropane-1-amine
Show/Hide
|
C17H25N3S
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0492852
|
2-(1H-Imidazol-4-yl)-N-methyl-3-(4-(trifluoromethyl)phenylthio)propane-1-amine
Show/Hide
|
C14H16F3N3S
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0041493
|
Clobenpropit
Show/Hide
|
C14H17ClN4S
|
5
|
| 1 |
IC50 = 0.7943 nM
|
|
|
| 2 |
Kd = 0.1 nM
|
|
|
| 3 |
Ki = 0.3388 nM
|
|
|
| 4 |
Ki = 0.58 nM
|
|
|
| 5 |
Ki = 2.4 nM
|
|
|
|
CP0886406
|
3-(piperidin-1-yl)propyl 4-(4-cyanophenyl)butylcarbamimidothioate hydrochloride
Show/Hide
|
C20H31ClN4S
|
2
|
| 1 |
IC50 = 1.995 nM
|
|
|
| 2 |
Kd = 1.995 nM
|
|
|
|
CP0554627
|
US9029381, 24
Show/Hide
|
C18H24N2O
|
1
|
| 1 |
IC50 = 3.41 nM
|
|
|
|
CP0873816
|
3-(piperidin-1-yl)propyl 4-(piperidin-1-yl)butylcarbamimidothioate hydrochloride
Show/Hide
|
C18H37ClN4S
|
2
|
| 1 |
IC50 = 6.31 nM
|
|
|
| 2 |
Kd = 1.995 nM
|
|
|
|
CP0873821
|
N-[4-(4-chlorophenyl)butyl]-S-[3-(piperidin-1-yl)propyl]-isothiourea hydrochloride
Show/Hide
|
C19H31Cl2N3S
|
2
|
| 1 |
IC50 = 6.31 nM
|
|
|
| 2 |
Kd = 0.2512 nM
|
|
|
|
CP0884564
|
3-(piperidin-1-yl)propyl 3-(4-chlorophenyl)propylcarbamimidothioate hydrochloride
Show/Hide
|
C18H29Cl2N3S
|
2
|
| 1 |
IC50 = 6.31 nM
|
|
|
| 2 |
Kd = 1.995 nM
|
|
|
|
CP0563094
|
US9029381, 13
Show/Hide
|
C18H23BrN2O
|
1
|
| 1 |
IC50 = 6.813 nM
|
|
|
|
CP0893896
|
3-(piperidin-1-yl)propyl 4-chlorophenethylcarbamimidothioate hydrochloride
Show/Hide
|
C17H27Cl2N3S
|
2
|
| 1 |
IC50 = 7.943 nM
|
|
|
| 2 |
Kd = 39.81 nM
|
|
|
|
CP0563900
|
US9029381, 30
Show/Hide
|
C19H27N3O3S
|
1
|
| 1 |
IC50 = 8.594 nM
|
|
|
|
CP0873819
|
3-(piperidin-1-yl)propyl 4-(4-(trifluoromethyl)phenyl)butylcarbamimidothioate hydrochloride
Show/Hide
|
C20H31ClF3N3S
|
2
|
| 1 |
IC50 = 15.85 nM
|
|
|
| 2 |
Kd = 12.59 nM
|
|
|
|
CP0514638
|
US9029381, 21
Show/Hide
|
C19H23N3O
|
1
|
| 1 |
IC50 = 17.5 nM
|
|
|
|
CP0921292
|
3-(pyrrolidin-1-yl)propyl 4-chlorobenzylcarbamimidothioate hydrochloride
Show/Hide
|
C15H23Cl2N3S
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0474485
|
US9029381, 46
Show/Hide
|
C22H26N4O
|
1
|
| 1 |
IC50 = 20.24 nM
|
|
|
|
CP0462838
|
US9029381, 34
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
IC50 = 23.86 nM
|
|
|
|
CP0873820
|
3-(piperidin-1-yl)propyl 5-phenylpentylcarbamimidothioate hydrochloride
Show/Hide
|
C20H34ClN3S
|
2
|
| 1 |
IC50 = 31.62 nM
|
|
|
| 2 |
Kd = 10 nM
|
|
|
|
CP0886407
|
3-(pyrrolidin-1-yl)propyl 4-chlorophenethylcarbamimidothioate hydrochloride
Show/Hide
|
C16H25Cl2N3S
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0963537
|
US9029381, 20
Show/Hide
|
C21H26N4O
|
1
|
| 1 |
IC50 = 33.92 nM
|
|
|
|
CP0466966
|
US9029381, 7
Show/Hide
|
C17H24N2O
|
1
|
| 1 |
IC50 = 39.68 nM
|
|
|
|
CP0876819
|
3-(piperidin-1-yl)propyl 4-chlorobenzylcarbamimidothioate hydrochloride
Show/Hide
|
C16H25Cl2N3S
|
2
|
| 1 |
IC50 = 79.43 nM
|
|
|
| 2 |
Kd = 39.81 nM
|
|
|
|
CP0873818
|
N-(4-(4-chlorophenyl)butyl)-4-(piperidin-1-yl)butanamide hydrochloride
Show/Hide
|
C19H30Cl2N2O
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0886405
|
4-(piperidin-1-yl)-N-(4-(4-(trifluoromethyl)phenyl)butyl)butanamide hydrochloride
Show/Hide
|
C20H30ClF3N2O
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0556596
|
US9029381, 45
Show/Hide
|
C15H24N4O
|
1
|
| 1 |
IC50 = 127.3 nM
|
|
|
|
CP0550230
|
US9029381, 17
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
IC50 = 196.5 nM
|
|
|
|
CP0516795
|
US9029381, 15
Show/Hide
|
C18H23BrN2O
|
1
|
| 1 |
IC50 = 262 nM
|
|
|
|
CP0851407
|
5-(4-chlorophenyl)-N-(3-(piperidin-1-yl)propyl)pentanamide hydrochloride
Show/Hide
|
C19H30Cl2N2O
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0901744
|
3-morpholinopropyl 4-chlorophenethylcarbamimidothioate hydrochloride
Show/Hide
|
C16H25Cl2N3OS
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0561905
|
US9029381, 25
Show/Hide
|
C18H24N2O
|
1
|
| 1 |
IC50 = 870.4 nM
|
|
|
|
CP0933714
|
3-(4-methylpiperazin-1-yl)propyl 4-chlorobenzylcarbamimidothioate hydrochloride
Show/Hide
|
C16H26Cl2N4S
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0902680
|
3-morpholinopropyl 4-chlorobenzylcarbamimidothioate hydrochloride
Show/Hide
|
C15H23Cl2N3OS
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0535916
|
US9029381, 31
Show/Hide
|
C17H24N2O
|
1
|
| 1 |
IC50 = 3534 nM
|
|
|
|
CP0895877
|
3-(piperazin-1-yl)propyl 4-chlorobenzylcarbamimidothioate hydrochloride
Show/Hide
|
C15H24Cl2N4S
|
1
|
| 1 |
IC50 = 6309.57 nM
|
|
|
|
CP0467369
|
1-[3-[4-[2-(piperidin-1-ylmethyl)phenyl]phenoxy]propyl]piperidine
Show/Hide
|
C26H36N2O
|
1
|
| 1 |
Ki = 0.045 nM
|
|
|
|
CP0482481
|
1-[3-[4-[4-[(Z)-3-piperidin-1-ylprop-1-enyl]phenyl]phenoxy]propyl]piperidine
Show/Hide
|
C28H38N2O
|
1
|
| 1 |
Ki = 0.057 nM
|
|
|
|
CP0250211
|
(7-Chloro-quinolin-4-yl)-[4-(3-piperidin-1-yl-propoxy)-phenyl]-amine; Oxalic acid
Show/Hide
|
C23H26ClN3O
|
2
|
| 1 |
Ki = 0.07943 nM
|
|
|
| 2 |
Ki = 0.086 nM
|
|
|
|
CP0371364
|
N-[4-(3-piperidin-1-ylpropoxy)phenyl]quinolin-4-amine
Show/Hide
|
C23H27N3O
|
3
|
| 1 |
Ki = 0.091 nM
|
|
|
| 2 |
Ki = 0.1 nM
|
|
|
| 3 |
Ki = 0.5 nM
|
|
|
|
CP0471521
|
1-[3-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]phenoxy]propyl]piperidine
Show/Hide
|
C28H40N2O2
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0475237
|
US9216182, 1.60
Show/Hide
|
C21H30N4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0479761
|
1-[3-[4-[4-(4-piperidin-1-ylbutoxy)phenyl]phenoxy]propyl]piperidine
Show/Hide
|
C29H42N2O2
|
1
|
| 1 |
Ki = 0.13 nM
|
|
|
|
CP0467353
|
1-[3-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]phenyl]propyl]piperidine
Show/Hide
|
C28H40N2O
|
1
|
| 1 |
Ki = 0.17 nM
|
|
|
|
CP0418140
|
US9216182, 1.63
Show/Hide
|
C21H32N4O3
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0441661
|
US9216182, 1.59
Show/Hide
|
C20H30N4O4
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0516110
|
US9216182, 1.62
Show/Hide
|
C20H30N4O3
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0444030
|
1-methyl-4-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]phenyl]piperazine
Show/Hide
|
C25H35N3O
|
1
|
| 1 |
Ki = 0.23 nM
|
|
|
|
CP0056747
|
4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)-1(2H)-phthalazinone
Show/Hide
|
C39H49ClN4O2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0372189
|
2-[1-[3-[4-[3-(azepan-1-yl)propoxy]phenyl]propyl]azepan-4-yl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C39H49ClN4O2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0372190
|
2-[[(2S)-1-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]pyrrolidin-2-yl]methyl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C39H49ClN4O2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0503437
|
N-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]butyl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C31H41N3O
|
2
|
| 1 |
Ki = 0.255273 nM
|
|
|
| 2 |
Ki = 1.995 nM
|
|
|
|
CP0413257
|
US9216182, 1.78
Show/Hide
|
C17H26N4O2S
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0475236
|
US9216182, 1.38
Show/Hide
|
C20H30N4O3
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0549988
|
US9216182, 1.64
Show/Hide
|
C20H32N4O3
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0216075
|
N-[2-[4-(3-piperidin-1-ylpropoxy)phenyl]ethyl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C29H37N3O
|
2
|
| 1 |
Ki = 0.3162 nM
|
|
|
| 2 |
Ki = 0.33 nM
|
|
|
|
CP0872588
|
4-(4-(azetidine-1-carbonyl)benzoyl)-1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C31H38N4O6
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0377778
|
2-[[(2R)-1-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]pyrrolidin-2-yl]methyl]-4-[(4-methoxyphenyl)methyl]phthalazin-1-one
Show/Hide
|
C40H52N4O3
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0468325
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-benzylquinolin-2-yl]propanoic acid
Show/Hide
|
C40H50N4O3
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0869694
|
1-(3,4-Dimethoxy-phenyl)-4-[4-(1-ethyl-propyl)-piperazin-1-yl]-butane-1,4-dione hydrochloride
Show/Hide
|
C21H33ClN2O4
|
1
|
| 1 |
Ki = 0.38 nM
|
|
|
|
CP0377779
|
2-[[(2R)-1-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]pyrrolidin-2-yl]methyl]-4-[(4-hydroxyphenyl)methyl]phthalazin-1-one
Show/Hide
|
C39H50N4O3
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0437972
|
2-[2-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butylamino]ethyl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C36H45ClN4O2
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0466023
|
2-[[(2R)-1-[5-[4-[3-(azepan-1-yl)propoxy]phenyl]pentyl]pyrrolidin-2-yl]methyl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C40H51ClN4O2
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0465007
|
8-[4-[3-[4-[3-(azepan-1-yl)propoxy]phenyl]propyl]piperazin-1-yl]quinoline
Show/Hide
|
C31H42N4O
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0070231
|
3-methyl-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-6,7-dihydro-5H-cyclopenta[d]pyridazin-4-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0413256
|
US9216182, 1.73
Show/Hide
|
C21H29N5O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0419333
|
US9216182, 1.50
Show/Hide
|
C20H27N5O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0441627
|
US9216182, 1.19
Show/Hide
|
C19H28N4O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0441662
|
US9216182, 1.67
Show/Hide
|
C19H28N4O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0455993
|
US9216182, 1.52
Show/Hide
|
C21H30N4O4
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0475238
|
US9216182, 1.61
Show/Hide
|
C19H30N4O3
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0518189
|
US9216182, 1.33
Show/Hide
|
C19H27FN4O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0518194
|
US9216182, 1.74
Show/Hide
|
C21H31N5O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0946883
|
1-[4-(1-Ethyl-propyl)-piperazin-1-yl]-4-(3-fluoro-4-trifluoromethoxy-phenyl)-butane-1,4-dione hydrochloride
Show/Hide
|
C20H30ClFN2O3
|
1
|
| 1 |
Ki = 0.43 nM
|
|
|
|
CP0473343
|
1-[3-[4-[4-(2-piperidin-1-ylethoxy)phenyl]phenoxy]propyl]piperidine
Show/Hide
|
C27H38N2O2
|
1
|
| 1 |
Ki = 0.49 nM
|
|
|
|
CP0197280
|
3-methyl-1-[4-(3-piperidin-1-ylpropoxy)phenyl]-6,7-dihydro-5H-cyclopenta[d]pyridazin-4-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0556257
|
US9034874, 2.2
Show/Hide
|
C19H28N4O3
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0418112
|
US9216182, 1.37
Show/Hide
|
C19H30N4O3
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0418142
|
US9216182, 1.56
Show/Hide
|
C19H30N4O3
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0557878
|
US9216182, 1.71
Show/Hide
|
C19H29N5O3
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0196630
|
N-[2-[4-(3-piperidin-1-ylpropoxy)phenyl]ethyl]quinolin-4-amine
Show/Hide
|
C25H31N3O
|
2
|
| 1 |
Ki = 0.5012 nM
|
|
|
| 2 |
Ki = 0.53 nM
|
|
|
|
CP0279643
|
(7-Chloro-quinolin-4-yl)-{2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-ethyl}-amine; Oxalic acid
Show/Hide
|
C25H30ClN3O
|
2
|
| 1 |
Ki = 0.5012 nM
|
|
|
| 2 |
Ki = 3.39 nM
|
|
|
|
CP0860700
|
(R)-4-(1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C27H32N4O5
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0372188
|
2-[1-[[4-[3-(azepan-1-yl)propoxy]phenyl]methyl]azepan-4-yl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C37H45ClN4O2
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0450306
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-2-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0450310
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline
Show/Hide
|
C30H40N4O
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0555840
|
1-[3-[4-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]phenoxy]propyl]piperidine
Show/Hide
|
C29H42N2O2
|
1
|
| 1 |
Ki = 0.51 nM
|
|
|
|
CP0478889
|
(E)-1,3-bis[4-(3-piperidin-1-ylpropoxy)phenyl]prop-2-en-1-one
Show/Hide
|
C31H42N2O3
|
1
|
| 1 |
Ki = 0.53 nM
|
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CP0900298
|
1-(4-Chloro-phenyl)-4-[4-(1,1-dimethyl-propyl)-piperazin-1-yl]-butane-1,4-dione hydrochloride
Show/Hide
|
C19H28Cl2N2O2
|
1
|
| 1 |
Ki = 0.54 nM
|
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CP0478888
|
1-[3-[4-[3-(piperidin-1-ylmethyl)phenyl]phenoxy]propyl]piperidine
Show/Hide
|
C26H36N2O
|
1
|
| 1 |
Ki = 0.549 nM
|
|
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|
CP0159107
|
2-[[(2R)-1-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]pyrrolidin-2-yl]methyl]-4-[(4-chlorophenyl)methyl]pyrido[3,4-d]pyridazin-1-one
Show/Hide
|
C38H48ClN5O2
|
1
|
| 1 |
Ki = 0.5623 nM
|
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CP0447757
|
2-[4-(4-fluorobenzoyl)piperazin-1-yl]-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C27H34FN3O3
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
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CP0557889
|
US9216182, 1.58
Show/Hide
|
C19H29N5O3
|
1
|
| 1 |
Ki = 0.6 nM
|
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|
CP0748832
|
(R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki = 0.631 nM
|
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CP0854415
|
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(4-fluorobenzoyl)piperazin-2-one hydrochloride
Show/Hide
|
C26H31ClFN3O3
|
1
|
| 1 |
Ki = 0.631 nM
|
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CP0890876
|
4-(4-chlorobenzoyl)-1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C26H31Cl2N3O3
|
1
|
| 1 |
Ki = 0.631 nM
|
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|
CP0890877
|
(R)-4-(4-fluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H32FN3O5
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
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CP0906031
|
4-(4-(azetidine-1-carbonyl)benzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C30H38N4O6
|
1
|
| 1 |
Ki = 0.631 nM
|
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CP0915882
|
(R)-4-(3,5-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki = 0.631 nM
|
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CP0450309
|
8-[4-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]piperazin-1-yl]quinoline
Show/Hide
|
C32H44N4O
|
1
|
| 1 |
Ki = 0.631 nM
|
|
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CP0489390
|
1,3-bis[4-(3-piperidin-1-ylpropoxy)phenyl]propan-1-one
Show/Hide
|
C31H44N2O3
|
1
|
| 1 |
Ki = 0.64 nM
|
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CP0444031
|
1-[3-[4-[4-[(E)-3-piperidin-1-ylprop-1-enyl]phenyl]phenoxy]propyl]piperidine
Show/Hide
|
C28H38N2O
|
1
|
| 1 |
Ki = 0.655 nM
|
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CP0482482
|
1-[3-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]phenyl]prop-2-ynyl]piperidine
Show/Hide
|
C28H36N2O
|
1
|
| 1 |
Ki = 0.67 nM
|
|
|
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CP0413254
|
US9216182, 1.57
Show/Hide
|
C19H27N5O2
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0475769
|
US9216182, 1.43
Show/Hide
|
C23H33N5O3
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
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CP0549986
|
US9216182, 1.54
Show/Hide
|
C21H32N4O3
|
1
|
| 1 |
Ki = 0.7 nM
|
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|
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CP0922336
|
4-{3-[4-(1-Ethyl-propyl)-piperazin-1-yl]-3-oxo-propoxy}-benzonitrile hydrochloride
Show/Hide
|
C19H28ClN3O2
|
1
|
| 1 |
Ki = 0.74 nM
|
|
|
|
CP0296666
|
N-[3-[4-(3-piperidin-1-ylpropoxy)phenyl]propyl]quinolin-4-amine
Show/Hide
|
C26H33N3O
|
2
|
| 1 |
Ki = 0.75 nM
|
|
|
| 2 |
Ki = 0.7943 nM
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CP0845124
|
4-(1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C27H32N4O5
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
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CP0845131
|
4-(1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C29H34N4O5
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0896098
|
4-(4-methylbenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C26H34ClN3O3
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0902706
|
4-(4-fluorobenzoyl)-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C25H30FN3O5
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0915879
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(4-(methylsulfonyl)benzoyl)piperazin-2-one formic acid
Show/Hide
|
C29H37N3O7S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
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CP0915880
|
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(3,5-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C27H31F2N3O5
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0450305
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-butylquinolin-2-yl]propanoic acid
Show/Hide
|
C37H52N4O3
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0062835
|
2-methyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]phthalazin-1-one
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0271769
|
2-methyl-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5,6,7,8-tetrahydrophthalazin-1-one
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0490291
|
2-methyl-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]phthalazin-1-one
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0855337
|
1-(4-Chloro-phenyl)-4-[4-(1-ethyl-propyl)-piperazin-1-yl]-butane-1,4-dione hydrochloride
Show/Hide
|
C19H28Cl2N2O2
|
1
|
| 1 |
Ki = 0.86 nM
|
|
|
|
CP0482220
|
2-methyl-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]isoquinolin-1-one
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0423908
|
2-[4-(1-methylpyrrole-2-carbonyl)piperazin-1-yl]-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C26H36N4O3
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0473340
|
1-[3-[4-[3-[4-(3-piperidin-1-ylpropoxy)phenyl]propyl]phenoxy]propyl]piperidine
Show/Hide
|
C31H46N2O2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0561445
|
US9034874, 2.3
Show/Hide
|
C18H28N4O3
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0514986
|
US9216182, 1.48
Show/Hide
|
C21H29N5O2S
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0846920
|
2-(4-Dimethylamino-phenyl)-1-[4-(1-ethyl-propyl)-piperazin-1-yl]-ethanone dihydrochloride
Show/Hide
|
C19H33Cl2N3O
|
1
|
| 1 |
Ki = 0.96 nM
|
|
|
|
CP0681610
|
4-(1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C28H32N4O5
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0873040
|
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(4-methylbenzoyl)piperazin-2-one hydrochloride
Show/Hide
|
C27H34ClN3O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0376707
|
4-(1H-imidazol-5-ylmethyl)-1-methylpiperidine
Show/Hide
|
C10H17N3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0388224
|
4-((1H-Imidazol-4-yl)methyl)-1-(3-(trifluoromethyl)-phenyl)piperidine
Show/Hide
|
C16H18F3N3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0452149
|
4-((1H-Imidazol-4-yl)methyl)-1-(3-isopropylphenyl)piperidine
Show/Hide
|
C18H25N3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0418114
|
US9216182, 1.49
Show/Hide
|
C19H27F3N4O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0368828
|
US9034874, 1.5
Show/Hide
|
C19H29N5O3
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0475240
|
US9216182, 1.76
Show/Hide
|
C16H26N4O2S
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0478769
|
US9216182, 1.69
Show/Hide
|
C19H29N5O3
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0488713
|
US9216182, 1.92
Show/Hide
|
C16H25N5O2S
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0549973
|
US9216182, 1.70
Show/Hide
|
C18H29N5O3
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0557890
|
US9216182, 1.66
Show/Hide
|
C18H28N4O2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0899340
|
1-(4-Chloro-phenyl)-4-(4-cyclobutyl-piperazin-1-yl)-butane-1,4-dione hydrochloride
Show/Hide
|
C18H24Cl2N2O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0922334
|
3-(4-Chloro-phenoxy)-1-[4-(1-ethyl-propyl)-piperazin-1-yl]-propan-1-one hydrochloride
Show/Hide
|
C18H28Cl2N2O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0944629
|
1-(4-Chloro-phenyl)-4-(4-cyclopentyl-piperazin-1-yl)-butane-1,4-dione hydrochloride
Show/Hide
|
C19H26Cl2N2O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0470543
|
2-[4-(1-benzothiophene-2-carbonyl)piperazin-1-yl]-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C29H35N3O3S
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0564326
|
US9034874, 1.3
Show/Hide
|
C17H27N5O3
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0556850
|
1-[3-[4-[2-[4-(3-piperidin-1-ylpropoxy)phenyl]ethyl]phenoxy]propyl]piperidine
Show/Hide
|
C30H44N2O2
|
1
|
| 1 |
Ki = 1.212 nM
|
|
|
|
CP0343505
|
N-[3-[4-(3-piperidin-1-ylpropoxy)phenyl]propyl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C30H39N3O
|
2
|
| 1 |
Ki = 1.259 nM
|
|
|
| 2 |
Ki = 1.4 nM
|
|
|
|
CP0939742
|
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(4-(methylsulfonyl)benzoyl)piperazin-2-one formic acid
Show/Hide
|
C28H35N3O7S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0166950
|
2-[3-(1H-imidazol-4-ylmethyl)phenyl]-4,4,6-trimethyl-5,6-dihydro-4H-1,3-oxazine
Show/Hide
|
C17H21N3O
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0465009
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-7-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0512424
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-3-yl]propanoic acid
Show/Hide
|
C33H44N4O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0563242
|
US9034874, 1.1
Show/Hide
|
C18H27N5O3
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0899959
|
1-[4-(1-Ethyl-propyl)-piperazin-1-yl]-4-(4-trifluoromethyl-phenyl)-butane-1,4-dione hydrochloride
Show/Hide
|
C20H28ClF3N2O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0428302
|
4-(4-((1H-Imidazol-4-yl)methyl)piperidin-1-yl)-N,N-dimethylaniline
Show/Hide
|
C17H24N4
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0282219
|
2-methyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0271704
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-pyrimidin-2-ylpyridazin-3-one
Show/Hide
|
C22H25N5O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0473620
|
4-[4-[3-(azepan-1-yl)propoxy]phenyl]-2-methylphthalazin-1-one
Show/Hide
|
C24H29N3O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0475767
|
US9216182, 1.2
Show/Hide
|
C20H29N5O3
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0549985
|
US9216182, 1.51
Show/Hide
|
C20H30N4O4
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0230227
|
N-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]butyl]quinolin-4-amine
Show/Hide
|
C27H35N3O
|
2
|
| 1 |
Ki = 1.5 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
|
CP0942004
|
1-[4-(1-Ethyl-propyl)-piperazin-1-yl]-4-(4-fluoro-phenyl)-butane-1,4-dione hydrochloride
Show/Hide
|
C19H28ClFN2O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0070230
|
2-methyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]-5,6,7,8-tetrahydrophthalazin-1-one
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0490289
|
7-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-propylthieno[2,3-d]pyridazin-4-one
Show/Hide
|
C23H29N3O2S
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0406820
|
US9216182, 1.9
Show/Hide
|
C18H27FN4O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0509033
|
US9216182, 1.77
Show/Hide
|
C16H26N4O2S
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0549976
|
US9216182, 1.86
Show/Hide
|
C18H28N4O2S
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0574823
|
US9216182, 1.8
Show/Hide
|
C18H28N4O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0670657
|
4-(2-oxo-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazine-4-carbonyl)benzonitrile hydrochloride
Show/Hide
|
C26H31ClN4O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0681609
|
4-(4-fluoro-benzoyl)-1-[4-(3-piperidin-1-yl-propoxy)-phenyl]-piperazin-2-one formic acid
Show/Hide
|
C26H32FN3O5
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0845133
|
(S)-4-(1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C27H32N4O5
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0916136
|
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(2,4-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C27H31F2N3O5
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0450307
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-3-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0450308
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-2-yl]propanoic acid
Show/Hide
|
C33H44N4O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0461430
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-4-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0469081
|
(E)-3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-2-yl]prop-2-enoic acid
Show/Hide
|
C33H42N4O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0418459
|
4-(4-((1H-Imidazol-4-yl)methyl)piperidin-1-yl)-N-methylaniline
Show/Hide
|
C16H22N4
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0223879
|
3-methyl-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5,6,7,7a-tetrahydro-4aH-cyclopenta[d]pyridazin-4-one
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0556258
|
US9034874, 3.1
Show/Hide
|
C18H28N4O3
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0506721
|
US9216182, 1.29
Show/Hide
|
C21H30N4O4
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0518192
|
US9216182, 1.53
Show/Hide
|
C20H32N4O3
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0549987
|
US9216182, 1.55
Show/Hide
|
C19H30N4O3
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0555831
|
1-[3-[4-[4-(piperidin-1-ylmethyl)phenyl]phenoxy]propyl]piperidine
Show/Hide
|
C26H36N2O
|
1
|
| 1 |
Ki = 1.64 nM
|
|
|
|
CP0387781
|
2-methyl-4-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]phthalazin-1-one
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0402521
|
US9216182, 1.34
Show/Hide
|
C21H30N4O4
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0413249
|
US9216182, 1.24
Show/Hide
|
C20H30N4O4
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0418113
|
US9216182, 1.40
Show/Hide
|
C21H30N4O3
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0442821
|
US9216182, 1.42
Show/Hide
|
C21H34N4O3
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0442824
|
US9216182, 1.72
Show/Hide
|
C20H29N5O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0478767
|
US9216182, 1.25
Show/Hide
|
C18H27FN4O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0488706
|
US9216182, 1.3
Show/Hide
|
C21H31N5O3
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0518193
|
US9216182, 1.68
Show/Hide
|
C18H29N5O3
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0267668
|
(6-Piperidin-1-yl-hexyl)-(1,2,3,4-tetrahydro-acridin-9-yl)-amine; Oxalic acid
Show/Hide
|
C24H35N3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0438775
|
4-((1H-Imidazol-4-yl)methyl)-1-(4-(trifluoromethyl)-phenyl)piperidine
Show/Hide
|
C16H18F3N3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0467406
|
5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1-phenylpyridin-2-one
Show/Hide
|
C25H28N2O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0503415
|
6-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-2-methylpyridazin-3-one
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0418110
|
US9216182, 1.1
Show/Hide
|
C19H29N5O3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0442641
|
4-Benzyl-1H-imidazole derivative, 19
Show/Hide
|
C18H14N2
|
1
|
| 1 |
Ki = 1.82 nM
|
|
|
|
CP0431300
|
7-[4-(3-piperidin-1-ylpropoxy)phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one
Show/Hide
|
C23H29N3O2S
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0496092
|
5-methyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C19H27N3O2
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0078724
|
3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0114141
|
2-(4-benzoylpiperazin-1-yl)-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C27H35N3O3
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0495731
|
4-(4-fluoro-benzoyl)-1-[4-(3-piperidin-1-yl-propoxy)-phenyl]-piperazin-2-one formic acid
Show/Hide
|
C25H30FN3O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0860701
|
4-(3,5-difluorobenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0860703
|
4-(3,5-difluorobenzoyl)-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one
Show/Hide
|
C24H27F2N3O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0915877
|
4-(3,5-difluorobenzoyl)-1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0918635
|
4-(4-chlorobenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C25H31Cl2N3O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0494367
|
2-[1-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]azepan-4-yl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C40H51ClN4O2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0461431
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-6-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0464411
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-ethylquinolin-2-yl]propanoic acid
Show/Hide
|
C35H48N4O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0046463
|
3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C18H23N3O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0461426
|
1-benzyl-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0427350
|
2-benzyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4,5-dihydropyridazin-3-one
Show/Hide
|
C25H31N3O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0399074
|
4-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0189162
|
1-[4-(1'-cyclobutylspiro[3,4-dihydrochromene-2,4'-piperidine]-6-yl)oxypiperidin-1-yl]-2-methylpropan-1-one
Show/Hide
|
C26H38N2O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0399719
|
2-[4-(furan-2-carbonyl)piperazin-1-yl]-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C25H33N3O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0442820
|
US9216182, 1.41
Show/Hide
|
C23H35N5O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0442828
|
US9216182, 1.94
Show/Hide
|
C20H32N6O3S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0410374
|
2,2,2-trifluoro-1-[4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazin-1-yl]ethanone
Show/Hide
|
C22H30F3N3O3
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0488709
|
US9216182, 1.11
Show/Hide
|
C19H30N4O2
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0464857
|
US9216182, 1.20
Show/Hide
|
C18H27FN4O2
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0518195
|
US9216182, 1.80
Show/Hide
|
C17H28N4O2S
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0912806
|
1-[4-(1-Ethyl-propyl)-piperazin-1-yl]-2-(4-trifluoromethyl-phenyl)-ethanone hydrochloride
Show/Hide
|
C18H26ClF3N2O
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0062831
|
3-methyl-1-[4-(3-piperidin-1-ylpropoxy)phenyl]-5,6,7,7a-tetrahydro-4aH-cyclopenta[d]pyridazin-4-one
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0470798
|
US9034874, 1.4
Show/Hide
|
C17H25N5O3
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0412177
|
US9216182, 1.21
Show/Hide
|
C19H27F3N4O2
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0072372
|
2-methyl-6-[4-[(2S)-2-methyl-3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0508562
|
5-[(4-chlorophenyl)methyl]-7-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]thieno[2,3-d]pyridazin-4-one
Show/Hide
|
C27H28ClN3O2S
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0292222
|
6-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-2-methylpyridazin-3-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0561442
|
US9034874, 1.2
Show/Hide
|
C18H29N5O3
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0388461
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-phenylpyridazin-3-one
Show/Hide
|
C24H27N3O2
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0416089
|
1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-[4-(trifluoromethyl)piperidin-1-yl]ethanone
Show/Hide
|
C22H31F3N2O2
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0518188
|
US9216182, 1.30
Show/Hide
|
C19H30N4O3
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0513323
|
[4-methyl-2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1,3-thiazol-5-yl]-morpholin-4-ylmethanone
Show/Hide
|
C23H31N3O3S
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0845125
|
4-(4-chlorobenzoyl)-1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C25H31Cl2N3O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0845128
|
4-(cyclopropanecarbonyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C22H32ClN3O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0845130
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(3,5-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C28H33F2N3O5
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0845132
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(4-fluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C28H34FN3O5
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0860702
|
4-(4-(methylsulfonyl)benzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one
Show/Hide
|
C26H33N3O5S
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0915881
|
4-(2,4-difluorobenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0922335
|
1-[4-(1-Ethyl-propyl)-piperazin-1-yl]-2-(4-trifluoromethoxy-phenyl)-ethanone hydrochloride
Show/Hide
|
C18H26ClF3N2O2
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0204973
|
7-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one
Show/Hide
|
C23H29N3O2S
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0566707
|
US9216182, 1.36
Show/Hide
|
C18H28N4O3
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0942291
|
1-[4-(1-Ethyl-propyl)-piperazin-1-yl]-4-(4-trifluoromethoxy-phenyl)-butane-1,4-dione hydrochloride
Show/Hide
|
C20H28ClF3N2O3
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0077210
|
3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-5,5-dimethyl-1,4-dihydropyridazin-6-one
Show/Hide
|
C21H29N3O2
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0271597
|
6-[4-(1-cyclopentylpiperidin-4-yl)oxyphenyl]-2-methylpyridazin-3-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0442827
|
US9216182, 1.90
Show/Hide
|
C19H28N4O4S
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0455996
|
US9216182, 1.95
Show/Hide
|
C19H32N6O3S
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0943635
|
1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-benzyl]-piperazine oxalate
Show/Hide
|
C27H36N2O5
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0397274
|
4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C18H23N3O2
|
3
|
| 1 |
Ki = 2.8 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
| 3 |
Ki = 15 nM
|
|
|
|
CP0524999
|
2-(4-acetylpiperazin-1-yl)-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C22H33N3O3
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0845535
|
2-Biphenyl-4-yl-1-[4-(1-ethyl-propyl)-piperazin-1-yl]-ethanone hydrochloride
Show/Hide
|
C23H31ClN2O
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0078015
|
4-methyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0561443
|
US9034874, 1.6
Show/Hide
|
C19H31N5O3
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0406818
|
US9216182, 1.6
Show/Hide
|
C19H27N5O2
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0463912
|
US9216182, 1.13
Show/Hide
|
C22H34N4O4
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0549881
|
US9216182, 1.14
Show/Hide
|
C21H32N4O4
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0466127
|
2-(2-hydroxyethyl)-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C20H27N3O3
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0077317
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-pyridin-2-ylpyridazin-3-one
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0437563
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-thiophen-3-ylpyridazin-3-one
Show/Hide
|
C24H27N3O2S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0525071
|
1'-cyclobutyl-6-piperidin-4-yloxyspiro[3,4-dihydrochromene-2,4'-piperidine]
Show/Hide
|
C22H32N2O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0160985
|
4-[4-[(2S)-2-methyl-3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0447758
|
(4-fluorophenyl) 4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazine-1-carboxylate
Show/Hide
|
C27H34FN3O4
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0478768
|
US9216182, 1.31
Show/Hide
|
C20H32N4O3
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0466128
|
3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-pyridin-2-yl-1H-pyridazin-6-one
Show/Hide
|
C23H26N4O2
|
1
|
| 1 |
Ki = 3.1 nM
|
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CP0561444
|
US9034874, 2.1
Show/Hide
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C19H30N4O3
|
1
|
| 1 |
Ki = 3.1 nM
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CP0419331
|
US9216182, 1.44
Show/Hide
|
C22H33N5O3
|
1
|
| 1 |
Ki = 3.1 nM
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CP0845134
|
(S)-4-(4-fluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H32FN3O5
|
1
|
| 1 |
Ki = 3.162 nM
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CP0854404
|
(S)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki = 3.162 nM
|
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CP0860704
|
1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-4-pivaloylpiperazin-2-one hydrochloride
Show/Hide
|
C23H36ClN3O3
|
1
|
| 1 |
Ki = 3.162 nM
|
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CP0890878
|
4-(1-(4-(3-(azepan-1-yl)propoxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C28H34N4O5
|
1
|
| 1 |
Ki = 3.162 nM
|
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CP0896091
|
4-(4-chlorobenzoyl)-1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C28H34ClN3O5
|
1
|
| 1 |
Ki = 3.162 nM
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CP0918636
|
4-benzoyl-1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C26H32ClN3O3
|
1
|
| 1 |
Ki = 3.162 nM
|
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CP0920179
|
4-(3-(methylsulfonyl)benzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C27H35N3O7S
|
1
|
| 1 |
Ki = 3.162 nM
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CP0515620
|
4-Benzyl-1H-imidazole derivative, 21
Show/Hide
|
C15H16N2
|
1
|
| 1 |
Ki = 3.162 nM
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|
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CP0468326
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-5-carbonitrile
Show/Hide
|
C31H39N5O
|
1
|
| 1 |
Ki = 3.162 nM
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CP0387519
|
1-methyl-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C20H26N2O2
|
1
|
| 1 |
Ki = 3.2 nM
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CP0070556
|
3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C18H25N3O2
|
1
|
| 1 |
Ki = 3.2 nM
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CP0123612
|
methyl 4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazine-1-carboxylate
Show/Hide
|
C22H33N3O4
|
1
|
| 1 |
Ki = 3.2 nM
|
|
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CP0493228
|
US9216182, 1.89
Show/Hide
|
C17H27N5O3S
|
1
|
| 1 |
Ki = 3.3 nM
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|
|
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CP0574866
|
US9216182, 1.12
Show/Hide
|
C20H30N4O4
|
1
|
| 1 |
Ki = 3.3 nM
|
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CP0456101
|
2-(2-fluoroethyl)-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C20H26FN3O2
|
1
|
| 1 |
Ki = 3.4 nM
|
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CP0494534
|
5-methyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 3.4 nM
|
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CP0461427
|
1-methyl-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxopyridine-3-carbonitrile
Show/Hide
|
C21H25N3O2
|
1
|
| 1 |
Ki = 3.4 nM
|
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|
CP0410373
|
2-(3,3-difluoropyrrolidin-1-yl)-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C20H28F2N2O2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
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CP0542408
|
1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-(4-methylsulfonylpiperazin-1-yl)ethanone
Show/Hide
|
C21H33N3O4S
|
1
|
| 1 |
Ki = 3.4 nM
|
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CP0395112
|
1-methyl-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-3-phenylpyridin-2-one
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
Ki = 3.5 nM
|
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CP0456970
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-(4-fluorophenyl)-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C26H28FN3O2
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0406819
|
US9216182, 1.7
Show/Hide
|
C20H31N5O3
|
1
|
| 1 |
Ki = 3.5 nM
|
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|
CP0306982
|
(3-Methyl-quinolin-4-yl)-(6-piperidin-1-yl-hexyl)-amine; Oxalic acid
Show/Hide
|
C21H31N3
|
1
|
| 1 |
Ki = 3.6 nM
|
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CP0908316
|
1-(4-Chloro-phenyl)-4-(4-cyclohexyl-piperazin-1-yl)-butane-1,4-dione hydrochloride
Show/Hide
|
C20H28Cl2N2O2
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
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CP0123547
|
2-methyl-8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-5,6-dihydrobenzo[h]cinnolin-3-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 3.6 nM
|
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|
CP0473435
|
5-[4-(1-cyclopentylpiperidin-4-yl)oxyphenyl]-3-methyl-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0418111
|
US9216182, 1.28
Show/Hide
|
C20H30N4O4
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0441107
|
3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0258253
|
5-[4-(1-cyclopentylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0488708
|
US9216182, 1.5
Show/Hide
|
C21H33N5O3
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0055894
|
(1R,6S)-5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0511942
|
US9216182, 1.15
Show/Hide
|
C18H28N6O3
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0514988
|
US9216182, 1.82
Show/Hide
|
C19H28N4O4S
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0459565
|
2-ethyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0470541
|
phenyl 4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazine-1-carboxylate
Show/Hide
|
C27H35N3O4
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0845126
|
1-(4-(3-(azepan-1-yl)propoxy)phenyl)-4-(4-fluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C27H34FN3O5
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0845127
|
4-(2,4-difluorobenzoyl)-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one
Show/Hide
|
C24H27F2N3O3
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0854442
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(2,4-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C28H33F2N3O5
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0890879
|
4-benzoyl-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C25H32ClN3O3
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
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CP0896097
|
1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-4-(pyrazolo[1,5-a]pyrimidine-3-carbonyl)piperazin-2-one formic acid
Show/Hide
|
C26H32N6O5
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0900122
|
4-(2,4-difluorobenzoyl)-1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0904401
|
4-(4-fluorobenzoyl)-1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C25H31ClFN3O3
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0078631
|
4-[(1R,2R)-2-(5,5-Dimethyl-hex-1-ynyl)-cyclopropyl]-1H-imidazole
Show/Hide
|
C14H20N2
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0531920
|
2-[3-(1H-imidazol-4-ylmethyl)phenyl]-4,4-dimethyl-4,5-dihydro-1,3-oxazole
Show/Hide
|
C15H17N3O
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
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CP0460645
|
2-[1-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]azepan-4-yl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C38H47ClN4O2
|
1
|
| 1 |
Ki = 3.981 nM
|
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CP0194592
|
(R)-4-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofuran-5-yl)benzonitrile
Show/Hide
|
C22H22N2O
|
2
|
| 1 |
Ki = 4 nM
|
|
|
| 2 |
Ki = 9.1 nM
|
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CP0493662
|
(6-(3-(piperidin-1-yl)propoxy)naphthalen-2-yl)(pyrrolidin-1-yl)methanone
Show/Hide
|
C23H30N2O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0424450
|
5-propan-2-yl-7-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]thieno[2,3-d]pyridazin-4-one
Show/Hide
|
C22H27N3O2S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0399073
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-(6-methylpyridin-2-yl)pyridazin-3-one
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0441134
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-2,6-dimethylpyridazin-3-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0093208
|
1-[4-(1'-cyclobutylspiro[3,4-dihydrochromene-2,4'-piperidine]-6-yl)oxypiperidin-1-yl]ethanone
Show/Hide
|
C24H34N2O3
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0160988
|
2-(methoxymethyl)-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C20H27N3O3
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0416088
|
ethyl 4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazine-1-carboxylate
Show/Hide
|
C23H35N3O4
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0380706
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-methyl-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0466013
|
3-methyl-5-[4-(1-propan-2-ylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0488710
|
US9216182, 1.35
Show/Hide
|
C19H28N4O3
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0411150
|
4-(2-(4-Cyclohexylphenylamino)ethyl)-1H-imidazole
Show/Hide
|
C17H23N3
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0413251
|
US9216182, 1.26
Show/Hide
|
C19H27N5O2
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0413252
|
US9216182, 1.32
Show/Hide
|
C19H30N4O3
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0139334
|
8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-2-propan-2-yl-5,6-dihydrobenzo[h]cinnolin-3-one
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0410375
|
1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethanone
Show/Hide
|
C25H33N3O3S
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0419339
|
US9216182, 1.85
Show/Hide
|
C17H28N4O2S
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0508936
|
US9216182, 1.88
Show/Hide
|
C17H28N4O3S
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0070554
|
5,5-dimethyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1,4-dihydropyridazin-6-one
Show/Hide
|
C20H29N3O2
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0188655
|
8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-5,6-dihydro-2H-benzo[h]cinnolin-3-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0527296
|
US9216182, 1.87
Show/Hide
|
C18H28N4O4S
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0890537
|
1-(4-Chloro-phenyl)-4-(4-isopropyl-piperazin-1-yl)-butane-1,4-dione hydrochloride
Show/Hide
|
C17H24Cl2N2O2
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0499348
|
6-[3-chloro-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-methylpyridazin-3-one
Show/Hide
|
C19H24ClN3O2
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0457185
|
3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-4-methyl-1H-pyridazin-6-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0327320
|
4-Benzyl-1H-imidazole derivative, 18
Show/Hide
|
C16H18N2
|
1
|
| 1 |
Ki = 4.467 nM
|
|
|
|
CP0435364
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-ethyl-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0442816
|
US9216182, 1.16
Show/Hide
|
C20H30N4O3
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0490290
|
2-[(4-chlorophenyl)methyl]-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]phthalazin-1-one
Show/Hide
|
C29H30ClN3O2
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0525000
|
2-methylpropyl 4-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperazine-1-carboxylate
Show/Hide
|
C25H39N3O4
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0440670
|
1-(4-fluorophenyl)-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C25H27FN2O2
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0486636
|
5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0455995
|
US9216182, 1.91
Show/Hide
|
C15H25N5O2S
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0490005
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-propan-2-ylpyridazin-3-one
Show/Hide
|
C21H29N3O2
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0482218
|
1-methyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C20H26N2O2
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0455994
|
US9216182, 1.79
Show/Hide
|
C16H26N4O2S
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0433181
|
2-benzyl-6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]pyridazin-3-one
Show/Hide
|
C24H27N3O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0418921
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-(2,2,2-trifluoroethyl)-4,5-dihydropyridazin-3-one
Show/Hide
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C20H26F3N3O2
|
1
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| 1 |
Ki = 5 nM
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CP0428469
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2-methyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4,5-dihydropyridazin-3-one
Show/Hide
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C19H27N3O2
|
1
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| 1 |
Ki = 5 nM
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CP0210518
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4-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-methyl-1H-pyridazin-6-one
Show/Hide
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C20H25N3O2
|
1
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| 1 |
Ki = 5 nM
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CP0436424
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4-methoxy-2-(methoxymethyl)-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
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C21H29N3O4
|
1
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| 1 |
Ki = 5 nM
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CP0854444
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(S)-4-(3,5-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
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C26H31F2N3O5
|
1
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| 1 |
Ki = 5.012 nM
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CP0900120
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1-(4-(3-(azepan-1-yl)propoxy)phenyl)-4-(3,5-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
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C27H33F2N3O5
|
1
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| 1 |
Ki = 5.012 nM
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CP0401216
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3-[4-(1-cyclopentylpiperidin-4-yl)oxyphenyl]-1H-pyridazin-6-one
Show/Hide
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C20H25N3O2
|
1
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| 1 |
Ki = 5.1 nM
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CP0511943
|
US9216182, 1.18
Show/Hide
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C19H30N4O3
|
1
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| 1 |
Ki = 5.1 nM
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CP0514989
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US9216182, 1.93
Show/Hide
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C16H27N5O2S
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1
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| 1 |
Ki = 5.2 nM
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CP0400519
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4-((1H-Imidazol-4-yl)methyl)-1-(4-methoxyphenyl)piperidine
Show/Hide
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C16H21N3O
|
1
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| 1 |
Ki = 5.4 nM
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CP0066136
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1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-morpholin-4-ylethanone
Show/Hide
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C20H30N2O3
|
1
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| 1 |
Ki = 5.4 nM
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CP0531406
|
US9216182, 2.4
Show/Hide
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C18H27N5O3
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1
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| 1 |
Ki = 5.4 nM
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CP0488707
|
US9216182, 1.4
Show/Hide
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C19H27N5O3
|
1
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| 1 |
Ki = 5.5 nM
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CP0398250
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(4R)-3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
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C20H27N3O2
|
1
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| 1 |
Ki = 5.6 nM
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CP0494716
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6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-(2,2,2-trifluoroethyl)pyridazin-3-one
Show/Hide
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C20H24F3N3O2
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1
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| 1 |
Ki = 5.7 nM
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CP0072371
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6-[3-fluoro-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-methylpyridazin-3-one
Show/Hide
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C19H24FN3O2
|
1
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| 1 |
Ki = 5.8 nM
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CP0493227
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US9216182, 1.84
Show/Hide
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C17H28N4O3S
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1
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| 1 |
Ki = 5.8 nM
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CP0392530
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6-[6-(1-cyclopentylpiperidin-4-yl)oxypyridin-3-yl]-2-methylpyridazin-3-one
Show/Hide
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C20H26N4O2
|
1
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| 1 |
Ki = 5.9 nM
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CP0437564
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5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-(3-methylpyridin-2-yl)pyridazin-3-one
Show/Hide
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C26H30N4O2
|
1
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| 1 |
Ki = 6 nM
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CP0093209
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[4-(1'-cyclobutylspiro[3,4-dihydrochromene-2,4'-piperidine]-6-yl)oxypiperidin-1-yl]-cyclopropylmethanone
Show/Hide
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C26H36N2O3
|
1
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| 1 |
Ki = 6 nM
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CP0506719
|
US9216182, 1.17
Show/Hide
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C20H31N5O3
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1
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| 1 |
Ki = 6 nM
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CP0227894
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8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-5,6-dihydro-3H-benzo[f]cinnolin-2-one
Show/Hide
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C20H25N3O2
|
1
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| 1 |
Ki = 6.2 nM
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CP0442826
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US9216182, 1.83
Show/Hide
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C17H27N5O3S
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1
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| 1 |
Ki = 6.2 nM
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CP0488288
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3-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-1H-pyridazin-6-one
Show/Hide
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C18H22N4O2
|
1
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| 1 |
Ki = 6.3 nM
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CP0450683
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1-[2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-oxoethyl]piperidine-4-carbonitrile
Show/Hide
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C22H31N3O2
|
1
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| 1 |
Ki = 6.3 nM
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CP0845136
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4-(2-oxo-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
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C26H30N4O5
|
1
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| 1 |
Ki = 6.31 nM
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CP0488287
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6-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-2-propan-2-ylpyridazin-3-one
Show/Hide
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C21H28N4O2
|
1
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| 1 |
Ki = 6.5 nM
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CP0077302
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(1S,6R)-5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
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C20H25N3O2
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1
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| 1 |
Ki = 6.8 nM
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CP0428265
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2-benzyl-6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
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C25H29N3O2
|
1
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| 1 |
Ki = 6.9 nM
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CP0435366
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5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-propan-2-yl-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
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C23H31N3O2
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1
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| 1 |
Ki = 6.9 nM
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CP0066511
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1'-cyclobutyl-6-(1-methylsulfonylpiperidin-4-yl)oxyspiro[3,4-dihydrochromene-2,4'-piperidine]
Show/Hide
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C23H34N2O4S
|
1
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| 1 |
Ki = 7 nM
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CP0522574
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1'-cyclobutyl-6-(1-propan-2-ylsulfonylpiperidin-4-yl)oxyspiro[3,4-dihydrochromene-2,4'-piperidine]
Show/Hide
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C25H38N2O4S
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1
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| 1 |
Ki = 7 nM
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CP0549244
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1'-cyclobutyl-6-(1-ethylsulfonylpiperidin-4-yl)oxyspiro[3,4-dihydrochromene-2,4'-piperidine]
Show/Hide
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C24H36N2O4S
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1
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| 1 |
Ki = 7 nM
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CP0438280
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3-[3,5-difluoro-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C18H21F2N3O2
|
1
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| 1 |
Ki = 7.1 nM
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CP0398253
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3-[4-(1-cyclobutylpiperidin-4-yl)oxy-3-fluorophenyl]-5,5-dimethyl-1,4-dihydropyridazin-6-one
Show/Hide
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C21H28FN3O2
|
1
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| 1 |
Ki = 7.1 nM
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CP0509035
|
US9216182, 1.81
Show/Hide
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C18H28N4O4S
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1
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| 1 |
Ki = 7.3 nM
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CP0183657
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(6-Piperidin-1-yl-hexyl)-quinolin-4-yl-amine; Oxalic acid
Show/Hide
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C20H29N3
|
1
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| 1 |
Ki = 7.6 nM
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CP0391683
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5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridin-2-one
Show/Hide
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C19H24N2O2
|
1
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| 1 |
Ki = 7.7 nM
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CP0289796
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(7-Chloro-quinolin-4-yl)-(8-piperidin-1-yl-octyl)-amine; Oxalic acid
Show/Hide
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C22H32ClN3
|
1
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| 1 |
Ki = 7.8 nM
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CP0077209
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(4S)-3-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C20H27N3O2
|
1
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| 1 |
Ki = 7.8 nM
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CP0845129
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4-isonicotinoyl-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
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C25H32N4O5
|
1
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| 1 |
Ki = 7.943 nM
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CP0896096
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1-(4-(3-(azepan-1-yl)propoxy)phenyl)-4-(2,4-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C27H33F2N3O5
|
1
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| 1 |
Ki = 7.943 nM
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CP0507753
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2-[2-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl-methylamino]ethyl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
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C37H47ClN4O2
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1
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| 1 |
Ki = 7.943 nM
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CP0395345
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2-(4-chlorophenyl)-6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]pyridazin-3-one
Show/Hide
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C23H24ClN3O
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1
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| 1 |
Ki = 8 nM
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CP0847367
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1-(4-Chloro-phenyl)-4-(4-cyclopropylmethyl-piperazin-1-yl)-butane-1,4-dione hydrochloride
Show/Hide
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C18H24Cl2N2O2
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1
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| 1 |
Ki = 8.3 nM
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CP0849940
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1-[4-(1-Ethyl-propyl)-piperazin-1-yl]-3-(4-trifluoromethyl-phenyl)-propan-1-one hydrochloride
Show/Hide
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C19H28ClF3N2O
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1
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| 1 |
Ki = 8.5 nM
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CP0508446
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3-[4-(3-piperidin-1-ylpropoxy)phenyl]-1H-pyridazin-6-one
Show/Hide
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C18H23N3O2
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1
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| 1 |
Ki = 8.7 nM
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CP0452072
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3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-5-pyridin-2-yl-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C23H28N4O2
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1
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| 1 |
Ki = 8.8 nM
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CP0428470
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6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-propan-2-yl-4,5-dihydropyridazin-3-one
Show/Hide
|
C21H31N3O2
|
1
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| 1 |
Ki = 9 nM
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CP0093210
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1'-cyclobutyl-6-(1-cyclopropylsulfonylpiperidin-4-yl)oxyspiro[3,4-dihydrochromene-2,4'-piperidine]
Show/Hide
|
C25H36N2O4S
|
1
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| 1 |
Ki = 9 nM
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CP0432893
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2-(3,3-difluoropiperidin-1-yl)-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C21H30F2N2O2
|
1
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| 1 |
Ki = 9 nM
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CP0506718
|
US9216182, 1.10
Show/Hide
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C19H27F3N4O2
|
1
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| 1 |
Ki = 9 nM
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CP0159228
|
5-[4-(1-propan-2-ylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C19H25N3O2
|
1
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| 1 |
Ki = 9.1 nM
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CP0947412
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1-(4-Chloro-phenyl)-4-[4-(tetrahydro-pyran-4-yl)-piperazin-1-yl]-butane-1,4-dione hydrochloride
Show/Hide
|
C19H26Cl2N2O3
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1
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| 1 |
Ki = 9.2 nM
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CP0455351
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6-[4-[3-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]propoxy]phenyl]-2-methylpyridazin-3-one
Show/Hide
|
C19H25N3O3
|
1
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| 1 |
Ki = 9.2 nM
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CP0398252
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2-methyl-6-[4-(1-propan-2-ylpiperidin-4-yl)oxyphenyl]pyridazin-3-one
Show/Hide
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C19H25N3O2
|
1
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| 1 |
Ki = 9.2 nM
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CP0442832
|
US9216182, 3.2
Show/Hide
|
C17H23N5O2
|
1
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| 1 |
Ki = 9.2 nM
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CP0504663
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4,4-difluoro-1-[3-[4-[4-(3-piperidin-1-ylpropoxy)phenyl]phenoxy]propyl]piperidine
Show/Hide
|
C28H38F2N2O2
|
1
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| 1 |
Ki = 9.31 nM
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CP0437567
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6-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-2-pyridin-2-ylpyridazin-3-one
Show/Hide
|
C24H26N4O2
|
1
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| 1 |
Ki = 9.8 nM
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CP0320765
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(7-Chloro-quinolin-4-yl)-(7-piperidin-1-yl-heptyl)-amine; Oxalic acid
Show/Hide
|
C21H30ClN3
|
1
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| 1 |
Ki = 9.9 nM
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CP0461673
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3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4-pyridin-2-yl-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C23H28N4O2
|
1
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| 1 |
Ki = 9.9 nM
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CP0442818
|
US9216182, 1.27
Show/Hide
|
C19H27F3N4O2
|
1
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| 1 |
Ki = 9.9 nM
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CP0845135
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(3-(methylsulfonyl)benzoyl)piperazin-2-one formic acid
Show/Hide
|
C29H37N3O7S
|
1
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| 1 |
Ki = 10 nM
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CP0512832
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6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-pyridin-2-ylpyridazin-3-one
Show/Hide
|
C23H26N4O2
|
1
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| 1 |
Ki = 10 nM
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CP0461672
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6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-phenyl-4,5-dihydropyridazin-3-one
Show/Hide
|
C24H29N3O2
|
1
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| 1 |
Ki = 10 nM
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CP0475460
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5-methoxy-2-(methoxymethyl)-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C21H29N3O4
|
1
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| 1 |
Ki = 10 nM
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CP0512531
|
6-[3,5-difluoro-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-methylpyridazin-3-one
Show/Hide
|
C19H23F2N3O2
|
1
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| 1 |
Ki = 11 nM
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CP0473623
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2-[(4-chlorophenyl)methyl]-4-[4-(3-piperidin-1-ylpropoxy)phenyl]phthalazin-1-one
Show/Hide
|
C29H30ClN3O2
|
1
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| 1 |
Ki = 11 nM
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CP0134393
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2-(4,4-difluoropiperidin-1-yl)-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
Show/Hide
|
C21H30F2N2O2
|
1
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| 1 |
Ki = 11 nM
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CP0306902
|
(7-Chloro-quinolin-4-yl)-(10-piperidin-1-yl-decyl)-amine; Oxalic acid
Show/Hide
|
C24H36ClN3
|
1
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| 1 |
Ki = 12 nM
|
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CP0134516
|
A-349,821
Show/Hide
|
C26H34N2O3
|
1
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| 1 |
Ki = 12 nM
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CP0400527
|
4-((1H-Imidazol-4-yl)methyl)-1-(4-fluorophenyl)piperidine
Show/Hide
|
C15H18FN3
|
1
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| 1 |
Ki = 12 nM
|
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CP0466129
|
3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4-pyridin-2-yl-1H-pyridazin-6-one
Show/Hide
|
C23H26N4O2
|
1
|
| 1 |
Ki = 12 nM
|
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CP0499398
|
6-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-pyridin-2-yl-4,5-dihydropyridazin-3-one
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
Ki = 12 nM
|
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CP0398254
|
3-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-5,5-dimethyl-1,4-dihydropyridazin-6-one
Show/Hide
|
C20H28N4O2
|
1
|
| 1 |
Ki = 12 nM
|
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CP0478770
|
US9216182, 3.3
Show/Hide
|
C17H23F3N4O2
|
1
|
| 1 |
Ki = 12 nM
|
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CP0935744
|
1-(4-Chloro-phenyl)-4-(4-cyclopropyl-piperazin-1-yl)-butane-1,4-dione hydrochloride
Show/Hide
|
C17H22Cl2N2O2
|
1
|
| 1 |
Ki = 13.3 nM
|
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CP0388225
|
4-((1H-Imidazol-4-yl)methyl)-1-(4-tert-butylphenyl)piperidine
Show/Hide
|
C19H27N3
|
1
|
| 1 |
Ki = 14 nM
|
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CP0400265
|
4-((1H-Imidazol-4-yl)methyl)-1-(4-isopropylphenyl)piperidine
Show/Hide
|
C18H25N3
|
1
|
| 1 |
Ki = 14 nM
|
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CP0390401
|
4-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-1H-pyridazin-6-one
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
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CP0442831
|
US9216182, 2.3
Show/Hide
|
C18H25N5O2
|
1
|
| 1 |
Ki = 14 nM
|
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|
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CP0502351
|
(5-Piperidin-1-yl-pentyl)-quinolin-4-yl-amine; Oxalic acid
Show/Hide
|
C19H27N3
|
1
|
| 1 |
Ki = 15 nM
|
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CP0452668
|
(6-(1-isopropylpiperidin-4-yloxy)naphthalen-2-yl)(2-methylpyrrolidin-1-yl)methanone
Show/Hide
|
C24H32N2O2
|
1
|
| 1 |
Ki = 15 nM
|
|
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CP0528020
|
2-methyl-6-[4-[(2R)-2-methyl-3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0427598
|
4-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-3-methyl-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0398255
|
3-[6-(1-propan-2-ylpiperidin-4-yl)oxypyridin-3-yl]-1H-pyridazin-6-one
Show/Hide
|
C17H22N4O2
|
1
|
| 1 |
Ki = 15 nM
|
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|
CP0517470
|
8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-4,4a,5,6-tetrahydro-2H-benzo[h]cinnolin-3-one
Show/Hide
|
C20H27N3O2
|
1
|
| 1 |
Ki = 15 nM
|
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|
|
CP0400521
|
4-((1H-Imidazol-4-yl)methyl)-1-(naphthalen-2-yl)piperidine
Show/Hide
|
C19H21N3
|
1
|
| 1 |
Ki = 16 nM
|
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|
|
CP0494483
|
3-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-1H-pyridazin-6-one
Show/Hide
|
C17H21N3O2
|
1
|
| 1 |
Ki = 16 nM
|
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CP0499237
|
3-[4-[3-[(2S)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C18H23N3O2
|
1
|
| 1 |
Ki = 16 nM
|
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|
|
CP0503180
|
3-[2-fluoro-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C18H22FN3O2
|
1
|
| 1 |
Ki = 16 nM
|
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|
|
CP0430677
|
8-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-2-phenyl-5,6-dihydrobenzo[h]cinnolin-3-one
Show/Hide
|
C26H29N3O2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0442830
|
US9216182, 2.2
Show/Hide
|
C18H25F3N4O2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0406981
|
1-[4-[2-(diethylamino)ethoxy]phenyl]-3-[4-(2-methylpropoxy)phenyl]thiourea
Show/Hide
|
C23H33N3O2S
|
1
|
| 1 |
Ki = 16.8 nM
|
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|
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CP0474044
|
8-(1-cyclobutylpiperidin-4-yl)oxy-4,4a,5,6-tetrahydro-2H-benzo[h]cinnolin-3-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0154174
|
(7-Chloro-quinolin-4-yl)-(6-piperidin-1-yl-hexyl)-amine; Oxalic acid
Show/Hide
|
C20H28ClN3
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0499688
|
1-methyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C20H26N2O2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0124596
|
(2-Piperidin-1-yl-ethyl)-(1,2,3,4-tetrahydro-acridin-9-yl)-amine; Oxalic acid
Show/Hide
|
C20H27N3
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0400529
|
4-((1H-Imidazol-4-yl)methyl)-1-(4-nitrophenyl)piperidine
Show/Hide
|
C15H18N4O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0385548
|
4,4-dimethyl-3-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1,5-dihydropyridazin-6-one
Show/Hide
|
C20H29N3O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0542354
|
4-methoxy-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O3
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0494485
|
2-methyl-6-[4-(3-piperidin-1-ylpropoxy)phenyl]pyridazin-3-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0428471
|
4-methyl-3-[4-(3-piperidin-1-ylpropoxy)phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C19H27N3O2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0473622
|
7-[4-[3-(diethylamino)propoxy]phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one
Show/Hide
|
C22H29N3O2S
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0473624
|
7-[4-[3-(4-methylpiperidin-1-yl)propoxy]phenyl]-5-propylthieno[2,3-d]pyridazin-4-one
Show/Hide
|
C24H31N3O2S
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0897020
|
2-(4-Acetyl-phenyl)-1-[4-(1-ethyl-propyl)-piperazin-1-yl]-ethanone hydrochloride
Show/Hide
|
C19H29ClN2O2
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0410256
|
4-[4-[(2S)-2-methyl-3-piperidin-1-ylpropoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0514990
|
US9216182, 2.1
Show/Hide
|
C18H27N5O3
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0926736
|
4-butyl-1H-imidazole
Show/Hide
|
C7H12N2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0168356
|
(7-Chloro-quinolin-4-yl)-(5-piperidin-1-yl-pentyl)-amine; Oxalic acid
Show/Hide
|
C19H26ClN3
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0945250
|
1-[4-(4-Pyrrolidin-1-ylmethyl-benzyloxy)-phenyl]-ethanone oxalate
Show/Hide
|
C22H25NO6
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0428567
|
3-[6-(1-cyclopentylpiperidin-4-yl)oxypyridin-3-yl]-1H-pyridazin-6-one
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0922385
|
1-[4-(4-Imidazol-1-yl-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C24H27N3O5
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0385309
|
4-[4-[(2R)-2-methyl-3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0492594
|
(4-methoxypiperidin-1-yl)(6-(3-(piperidin-1-yl)propoxy)naphthalen-2-yl)methanone
Show/Hide
|
C25H34N2O3
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0535423
|
(6-((1S,6S)-7-isopropyl-7-azabicyclo[4.1.1]octan-3-yloxy)quinolin-2-yl)(morpholino)methanone
Show/Hide
|
C24H31N3O3
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0400525
|
4-((1H-Imidazol-4-yl)methyl)-1-phenylpiperidine
Show/Hide
|
C15H19N3
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0513526
|
3-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C17H21N3O
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0182036
|
(7-Chloro-quinolin-4-yl)-(12-piperidin-1-yl-dodecyl)-amine; Oxalic acid
Show/Hide
|
C26H40ClN3
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0341974
|
1-[3-(1H-imidazol-4-ylmethyl)phenyl]-3,3-dimethylbutan-1-one
Show/Hide
|
C16H20N2O
|
1
|
| 1 |
Ki = 32.36 nM
|
|
|
|
CP0573858
|
US9216182, 1.39
Show/Hide
|
C19H28N4O4
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0515619
|
4-Benzyl-1H-imidazole derivative, 14
Show/Hide
|
C16H14N2
|
1
|
| 1 |
Ki = 33.11 nM
|
|
|
|
CP0182873
|
(3-Piperidin-1-yl-propyl)-(1,2,3,4-tetrahydro-acridin-9-yl)-amine; Oxalic acid
Show/Hide
|
C21H29N3
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0895091
|
1-(4-Chloro-phenyl)-4-(4-cycloheptyl-piperazin-1-yl)-butane-1,4-dione hydrochloride
Show/Hide
|
C21H30Cl2N2O2
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0166560
|
(6-(1-isopropylpiperidin-4-yloxy)naphthalen-2-yl)(4-methylpiperidin-1-yl)methanone
Show/Hide
|
C25H34N2O2
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0401129
|
6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-2-phenylpyridazin-3-one
Show/Hide
|
C23H25N3O
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0398256
|
6-[6-(1-cyclobutylpiperidin-4-yl)oxypyridin-3-yl]-2-pyridin-2-ylpyridazin-3-one
Show/Hide
|
C23H25N5O2
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0511569
|
3-[6-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]pyridin-3-yl]-1H-pyridazin-6-one
Show/Hide
|
C17H22N4O2
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0127532
|
(6-(1-isobutylpiperidin-4-yloxy)naphthalen-2-yl)(4-methylpiperidin-1-yl)methanone
Show/Hide
|
C26H36N2O2
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0885774
|
1-[4-(4-Azepan-1-ylmethyl-benzyloxy)-phenyl]-ethanone hydrochloride
Show/Hide
|
C22H28ClNO2
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0499397
|
3-[4-[3-[(2S)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C18H25N3O2
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0528021
|
2-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]-5-(6-oxo-1H-pyridazin-3-yl)benzonitrile
Show/Hide
|
C19H22N4O2
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0392979
|
6-[4-(3-piperidin-1-ylpropoxy)phenyl]-2-(2,2,2-trifluoroethyl)-4,5-dihydropyridazin-3-one
Show/Hide
|
C20H26F3N3O2
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0549874
|
US9216182, 4.1
Show/Hide
|
C19H30N6O2
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0485933
|
2-[3-(1H-imidazol-4-ylmethyl)phenyl]-3-oxa-1-azaspiro[4.4]non-1-ene
Show/Hide
|
C17H19N3O
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0566705
|
US9216182, 3.1
Show/Hide
|
C17H25N5O3
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0442639
|
2-[3-(1H-imidazol-4-ylmethyl)phenyl]pyridine
Show/Hide
|
C15H13N3
|
1
|
| 1 |
Ki = 40.74 nM
|
|
|
|
CP0916441
|
1-[4-(4-Chloro-3-methyl-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C22H26ClNO5
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0442822
|
US9216182, 1.46
Show/Hide
|
C20H31N5O4
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0099745
|
4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole
Show/Hide
|
C16H18N2O2
|
2
|
| 1 |
Ki = 46 nM
|
|
|
| 2 |
Ki = 94 nM
|
|
|
|
CP0476369
|
6-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-2-pyridin-2-ylpyridazin-3-one
Show/Hide
|
C22H24N4O
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0410758
|
tert-butyl 4-(1'-cyclobutylspiro[3,4-dihydrochromene-2,4'-piperidine]-6-yl)oxypiperidine-1-carboxylate
Show/Hide
|
C27H40N2O4
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0450518
|
4-[4-[(2R)-2-methyl-3-piperidin-1-ylpropoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0396888
|
5-[(4-chlorophenyl)methyl]-7-[4-(3-piperidin-1-ylpropoxy)phenyl]thieno[2,3-d]pyridazin-4-one
Show/Hide
|
C27H28ClN3O2S
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0201354
|
N-methyl-N-(3-piperidin-1-ylpropyl)-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C22H31N3
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0532294
|
7-[4-[3-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]propoxy]phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one
Show/Hide
|
C24H31N3O3S
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0485609
|
[(1'R,3R,3'aS,6'S,8'R,9'aS,10'aR)-7-[(2S)-3,3-dimethyloxirane-2-carbonyl]-1'-formyl-1',6'-dimethyl-3'a-(methylamino)-2-oxospiro[1H-indole-3,2'-4,6,7,8,9,9a,10,10a-octahydro-3H-cyclopenta[b]quinolizine]-8'-yl] pentanoate
Show/Hide
|
C33H45N3O6
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0380162
|
1-(2,4-difluorophenyl)-3-[4-(3-piperidin-1-ylpropoxy)phenyl]urea
Show/Hide
|
C21H25F2N3O2
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0470833
|
N-(1H-benzimidazol-2-ylmethyl)-2-[(1S,2R)-2-(1H-imidazol-5-yl)cyclopropyl]ethanamine
Show/Hide
|
C16H19N5
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0878639
|
1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-ethanone oxime
Show/Hide
|
C21H26N2O2
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0484600
|
2-[3-(1H-imidazol-4-ylmethyl)phenyl]-1-oxa-3-azaspiro[4.5]dec-2-ene
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
Ki = 56.23 nM
|
|
|
|
CP0431115
|
(6-(1-isopropylpiperidin-4-yloxy)naphthalen-2-yl)(pyrrolidin-1-yl)methanone
Show/Hide
|
C23H30N2O2
|
1
|
| 1 |
Ki = 57 nM
|
|
|
|
CP0388226
|
4-((1H-Imidazol-4-yl)methyl)-1-(biphenyl-4-yl)piperidine
Show/Hide
|
C21H23N3
|
1
|
| 1 |
Ki = 61 nM
|
|
|
|
CP0422096
|
azetidin-1-yl-[6-(1-propan-2-ylpiperidin-4-yl)oxyquinolin-2-yl]methanone
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0537973
|
(6-(1-isopropylpiperidin-4-yloxy)naphthalen-2-yl)(4-methoxypiperidin-1-yl)methanone
Show/Hide
|
C25H34N2O3
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0916923
|
Cyclopropyl-[4-(4-piperidin-1-ylmethyl-benzyloxy)-phenyl]-methanone oxalate
Show/Hide
|
C25H29NO6
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0343431
|
(3-Methyl-quinolin-4-yl)-(3-piperidin-1-yl-propyl)-amine; Oxalic acid
Show/Hide
|
C18H25N3
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0392978
|
3-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C17H23N3O2
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0123588
|
N-methyl-N-(2-piperidin-1-ylethyl)-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C21H29N3
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0460644
|
4-[(4-chlorophenyl)methyl]-2-[2-(1-methylpyrrolidin-2-yl)ethyl]phthalazin-1-one
Show/Hide
|
C22H24ClN3O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0462897
|
4-[(4-methoxyphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0151539
|
(7-Chloro-quinolin-4-yl)-(4-piperidin-1-yl-butyl)-amine; Oxalic acid
Show/Hide
|
C18H24ClN3
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0388464
|
2-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
Show/Hide
|
C18H23N3O2
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0456238
|
2-methyl-6-[4-(2-pyrrolidin-1-ylethyl)phenyl]pyridazin-3-one
Show/Hide
|
C17H21N3O
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0392980
|
4-methyl-3-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-4,5-dihydro-1H-pyridazin-6-one
Show/Hide
|
C18H25N3O2
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0869722
|
1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-ethanone oxalate
Show/Hide
|
C23H27NO6
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0431301
|
2-methyl-4-[4-(2-piperidin-1-ylethoxy)phenyl]phthalazin-1-one
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0371363
|
(3-Piperidin-1-yl-propyl)-quinolin-4-yl-amine; Oxalic acid
Show/Hide
|
C17H23N3
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0376935
|
1-{4-[3-(1H-Imidazol-4-yl)-propoxymethyl]-phenyl}-ethanone
Show/Hide
|
C15H18N2O2
|
1
|
| 1 |
Ki = 87 nM
|
|
|
|
CP0942643
|
1-[4-(Indan-5-yloxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C24H29NO5
|
1
|
| 1 |
Ki = 87 nM
|
|
|
|
CP0439266
|
(S)-1-(6-(1-isopropylpiperidin-4-yloxy)quinoline-2-carbonyl)pyrrolidine-2-carbonitrile
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
Ki = 87 nM
|
|
|
|
CP0941092
|
1-[4-(4-Propoxy-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C24H31NO6
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0847532
|
1-(4-Chloro-phenyl)-4-[4-(1,1-dimethyl-prop-2-ynyl)-piperazin-1-yl]-butane-1,4-dione hydrochloride
Show/Hide
|
C19H24Cl2N2O2
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0534996
|
(4R)-4-benzyl-2-[3-(1H-imidazol-4-ylmethyl)phenyl]-4,5-dihydro-1,3-oxazole
Show/Hide
|
C20H19N3O
|
1
|
| 1 |
Ki = 89.13 nM
|
|
|
|
CP0122423
|
(4-Piperidin-1-yl-butyl)-quinolin-4-yl-amine; Oxalic acid
Show/Hide
|
C18H25N3
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0892176
|
Phenyl-[4-(4-piperidin-1-ylmethyl-benzyloxy)-benzyl]-amine oxalate
Show/Hide
|
C28H32N2O5
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0888739
|
1-[4-(4-Diethylaminomethyl-benzyloxy)-phenyl]-ethanone hydrochloride
Show/Hide
|
C20H26ClNO2
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0922556
|
1-[4-(5,6,7,8-Tetrahydro-naphthalen-2-yloxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C25H31NO5
|
1
|
| 1 |
Ki = 92 nM
|
|
|
|
CP0916719
|
[4-(1-Ethyl-propyl)-piperazin-1-yl]-(4-trifluoromethoxy-phenyl)-methanone hydrochloride
Show/Hide
|
C17H24ClF3N2O2
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0518190
|
US9216182, 1.45
Show/Hide
|
C19H29N5O4
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0442825
|
US9216182, 1.75
Show/Hide
|
C21H30N4O3
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0874645
|
1-[4-(4-Chloro-3-fluoro-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C21H23ClFNO5
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0452667
|
(4-(hydroxymethyl)piperidin-1-yl)(6-(3-(piperidin-1-yl)propoxy)naphthalen-2-yl)methanone
Show/Hide
|
C25H34N2O3
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0474217
|
2-benzyl-8-(3-piperidin-1-ylpropoxy)-5,6-dihydrobenzo[h]cinnolin-3-one
Show/Hide
|
C27H31N3O2
|
1
|
| 1 |
Ki = 105 nM
|
|
|
|
CP0957209
|
1-[4-(4-Iodo-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C21H24INO5
|
1
|
| 1 |
Ki = 107 nM
|
|
|
|
CP0897829
|
1-[4-(1-Ethyl-propyl)-piperazin-1-yl]-2-(4-trifluoromethoxy-phenoxy)-ethanone hydrochloride
Show/Hide
|
C18H26ClF3N2O3
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0492340
|
1-methyl-5-[3-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridin-2-one
Show/Hide
|
C20H26N2O2
|
1
|
| 1 |
Ki = 112 nM
|
|
|
|
CP0380117
|
1-(3,5-dichloro-4-methylphenyl)-3-[4-(3-piperidin-1-ylpropoxy)phenyl]urea
Show/Hide
|
C22H27Cl2N3O2
|
1
|
| 1 |
Ki = 112.3 nM
|
|
|
|
CP0895298
|
1-[4-(4-Bromo-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C21H24BrNO5
|
1
|
| 1 |
Ki = 114 nM
|
|
|
|
CP0899553
|
1-[4-(4-Methoxy-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C22H27NO6
|
1
|
| 1 |
Ki = 119 nM
|
|
|
|
CP0422095
|
azetidin-1-yl-[6-(3-piperidin-1-ylpropoxy)quinolin-2-yl]methanone
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 119 nM
|
|
|
|
CP0475239
|
US9216182, 1.65
Show/Hide
|
C20H29N5O3
|
1
|
| 1 |
Ki = 121 nM
|
|
|
|
CP0866963
|
1-[4-(4-Fluoro-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C21H24FNO5
|
1
|
| 1 |
Ki = 123 nM
|
|
|
|
CP0941094
|
1-[4-(4-Chloro-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C21H24ClNO5
|
1
|
| 1 |
Ki = 124 nM
|
|
|
|
CP0932425
|
1-[4-(4-Trifluoromethyl-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C22H24F3NO5
|
1
|
| 1 |
Ki = 125 nM
|
|
|
|
CP0492595
|
(6-(1-isopropylpiperidin-4-yloxy)quinolin-2-yl)(4-methoxypiperidin-1-yl)methanone
Show/Hide
|
C24H33N3O3
|
1
|
| 1 |
Ki = 125 nM
|
|
|
|
CP0372187
|
4-[(4-chlorophenyl)methyl]-2-(1-methylpiperidin-4-yl)phthalazin-1-one
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0494366
|
4-[(4-chlorophenyl)methyl]-2-[3-(dimethylamino)propyl]phthalazin-1-one
Show/Hide
|
C20H22ClN3O
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0957204
|
1-(4-p-Tolyloxymethyl-benzyl)-piperidine oxalate
Show/Hide
|
C22H27NO5
|
1
|
| 1 |
Ki = 126 nM
|
|
|
|
CP0400523
|
3-(4-((1H-Imidazol-4-yl)methyl)piperidin-1-yl)pyridine
Show/Hide
|
C14H18N4
|
1
|
| 1 |
Ki = 127 nM
|
|
|
|
CP0967471
|
1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-ethanone O-methyl-oxime oxalate
Show/Hide
|
C24H30N2O6
|
1
|
| 1 |
Ki = 129 nM
|
|
|
|
CP0294233
|
4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one
Show/Hide
|
C22H24ClN3O
|
2
|
| 1 |
Ki = 147.91 nM
|
|
|
| 2 |
Ki = 158.49 nM
|
|
|
|
CP0907802
|
1-[4-(3,4-Dimethyl-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C23H29NO5
|
1
|
| 1 |
Ki = 149 nM
|
|
|
|
CP0458348
|
3-[2-methoxy-4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
Show/Hide
|
C19H25N3O3
|
1
|
| 1 |
Ki = 152 nM
|
|
|
|
CP0537972
|
(4-(hydroxymethyl)piperidin-1-yl)(6-(1-isopropylpiperidin-4-yloxy)naphthalen-2-yl)methanone
Show/Hide
|
C25H34N2O3
|
1
|
| 1 |
Ki = 154 nM
|
|
|
|
CP0492152
|
3-(1H-imidazol-4-ylmethyl)benzonitrile
Show/Hide
|
C11H9N3
|
1
|
| 1 |
Ki = 154.88 nM
|
|
|
|
CP0942229
|
Cyclopentyl-[4-(4-piperidin-1-ylmethyl-benzyloxy)-phenyl]-methanone oxalate
Show/Hide
|
C27H33NO6
|
1
|
| 1 |
Ki = 157 nM
|
|
|
|
CP0493578
|
4-Benzyl-1H-imidazole derivative, 13
Show/Hide
|
C10H10N2
|
1
|
| 1 |
Ki = 162.18 nM
|
|
|
|
CP0847167
|
1-[4-(4-Ethyl-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C23H29NO5
|
1
|
| 1 |
Ki = 163 nM
|
|
|
|
CP0916934
|
1-[4-(3,4-Dichloro-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C21H23Cl2NO5
|
1
|
| 1 |
Ki = 167 nM
|
|
|
|
CP0869670
|
1-[4-(4-Butyl-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C25H33NO5
|
1
|
| 1 |
Ki = 169 nM
|
|
|
|
CP0501124
|
5-[4-(1-ethylpiperidin-4-yl)oxyphenyl]-3,4-diazabicyclo[4.1.0]hept-4-en-2-one
Show/Hide
|
C18H23N3O2
|
1
|
| 1 |
Ki = 173 nM
|
|
|
|
CP0442823
|
US9216182, 1.47
Show/Hide
|
C18H27N5O4
|
1
|
| 1 |
Ki = 182 nM
|
|
|
|
CP0481811
|
2-[[(1S,2R)-2-(1H-imidazol-5-yl)cyclopropyl]methyl]-1H-benzimidazole
Show/Hide
|
C14H14N4
|
1
|
| 1 |
Ki = 186 nM
|
|
|
|
CP0320129
|
Acridin-9-yl-(3-piperidin-1-yl-propyl)-amine; Oxalic acid
Show/Hide
|
C21H25N3
|
1
|
| 1 |
Ki = 188 nM
|
|
|
|
CP0371365
|
(2-Piperidin-1-yl-ethyl)-quinolin-4-yl-amine; Oxalic acid
Show/Hide
|
C16H21N3
|
1
|
| 1 |
Ki = 191 nM
|
|
|
|
CP0460643
|
4-(cyclohexylmethyl)-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H29N3O
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0513989
|
4-[(3-fluorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H22FN3O
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0885737
|
1-[4-(4-Cyclopentyl-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C26H33NO5
|
1
|
| 1 |
Ki = 201 nM
|
|
|
|
CP0931986
|
1-(4-Phenoxymethyl-benzyl)-piperidine oxalate
Show/Hide
|
C21H25NO5
|
1
|
| 1 |
Ki = 227 nM
|
|
|
|
CP0540258
|
(6-(1-isopropylpyrrolidin-3-yloxy)naphthalen-2-yl)(4-methylpiperidin-1-yl)methanone
Show/Hide
|
C24H32N2O2
|
1
|
| 1 |
Ki = 234 nM
|
|
|
|
CP0935510
|
1-[4-(4-Benzyl-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C28H31NO5
|
1
|
| 1 |
Ki = 238 nM
|
|
|
|
CP0535422
|
(6-(1-isopropylpiperidin-4-yloxy)quinolin-2-yl)(morpholino)methanone
Show/Hide
|
C22H29N3O3
|
1
|
| 1 |
Ki = 238 nM
|
|
|
|
CP0372193
|
4-[(3-methylphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C22H25N3O
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0377781
|
4-[(4-hydroxyphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0352451
|
5-[(4-chlorophenyl)methyl]-7-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrido[2,3-d]pyridazin-8-one
Show/Hide
|
C20H21ClN4O
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0913590
|
1-[4-(4-Isopropyl-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C24H31NO5
|
1
|
| 1 |
Ki = 253 nM
|
|
|
|
CP0957212
|
1-[4-(4-Propyl-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C24H31NO5
|
1
|
| 1 |
Ki = 257 nM
|
|
|
|
CP0484636
|
4-(1H-imidazol-4-ylmethyl)aniline
Show/Hide
|
C10H11N3
|
1
|
| 1 |
Ki = 257.04 nM
|
|
|
|
CP0499193
|
6-[4-[3-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]propoxy]phenyl]-2-methylpyridazin-3-one
Show/Hide
|
C19H25N3O3
|
1
|
| 1 |
Ki = 295 nM
|
|
|
|
CP0509375
|
(4-methylpiperidin-1-yl)(6-(3-(piperidin-1-yl)propoxy)quinolin-2-yl)methanone
Show/Hide
|
C24H33N3O2
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0504276
|
4-[(4-ethoxyphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0357237
|
8-[(4-chlorophenyl)methyl]-6-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrido[2,3-d]pyridazin-5-one
Show/Hide
|
C20H21ClN4O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0913591
|
1-(4-m-Tolyloxymethyl-benzyl)-piperidine oxalate
Show/Hide
|
C22H27NO5
|
1
|
| 1 |
Ki = 334 nM
|
|
|
|
CP0076207
|
N-methyl-N-(2-piperidin-1-ylethyl)quinolin-4-amine
Show/Hide
|
C17H23N3
|
1
|
| 1 |
Ki = 362 nM
|
|
|
|
CP0092136
|
(7-Chloro-quinolin-4-yl)-(3-piperidin-1-yl-propyl)-amine; Oxalic acid
Show/Hide
|
C17H22ClN3
|
1
|
| 1 |
Ki = 378 nM
|
|
|
|
CP0339883
|
4-[(4-chlorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H22ClN3O
|
2
|
| 1 |
Ki = 398.11 nM
|
|
|
| 2 |
Ki = 436.52 nM
|
|
|
|
CP0056748
|
1-[(4-chlorophenyl)methyl]-3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrido[3,4-d]pyridazin-4-one
Show/Hide
|
C20H21ClN4O
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0100763
|
4-[(4-chlorophenyl)methyl]-2-[[(2R)-1-(2-methoxyethyl)pyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C23H26ClN3O2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0159108
|
4-[(4-chlorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrido[3,4-d]pyridazin-1-one
Show/Hide
|
C20H21ClN4O
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0150985
|
N-methyl-N-(3-piperidin-1-ylpropyl)quinolin-4-amine
Show/Hide
|
C18H25N3
|
1
|
| 1 |
Ki = 411 nM
|
|
|
|
CP0463910
|
4-Benzyl-1H-imidazole derivative, 23
Show/Hide
|
C10H9BrN2
|
1
|
| 1 |
Ki = 416.87 nM
|
|
|
|
CP0442640
|
4-Benzyl-1H-imidazole derivative, 16
Show/Hide
|
C15H13N3
|
1
|
| 1 |
Ki = 426.58 nM
|
|
|
|
CP0367946
|
2-[[(2R)-1-butylpyrrolidin-2-yl]methyl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C24H28ClN3O
|
1
|
| 1 |
Ki = 436.52 nM
|
|
|
|
CP0942178
|
1-(4-Chloro-phenyl)-4-(4-cyclooctyl-piperazin-1-yl)-butane-1,4-dione hydrochloride
Show/Hide
|
C22H32Cl2N2O2
|
1
|
| 1 |
Ki = 450 nM
|
|
|
|
CP0967489
|
1-(4-Chloro-phenyl)-4-[4-(1-propyl-butyl)-piperazin-1-yl]-butane-1,4-dione hydrochloride
Show/Hide
|
C21H32Cl2N2O2
|
1
|
| 1 |
Ki = 480 nM
|
|
|
|
CP0932429
|
1-[4-(4-Phenoxy-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C27H29NO6
|
1
|
| 1 |
Ki = 530 nM
|
|
|
|
CP0463909
|
4-Benzyl-1H-imidazole derivative, 24
Show/Hide
|
C16H18N2
|
1
|
| 1 |
Ki = 537.03 nM
|
|
|
|
CP0918692
|
1-[4-(4-Benzyloxy-phenoxymethyl)-benzyl]-piperidine oxalate
Show/Hide
|
C28H31NO6
|
1
|
| 1 |
Ki = 550 nM
|
|
|
|
CP0472129
|
(4-methylpiperidin-1-yl)(6-(2-(1-methylpyrrolidin-2-yl)ethoxy)naphthalen-2-yl)methanone
Show/Hide
|
C24H32N2O2
|
1
|
| 1 |
Ki = 571 nM
|
|
|
|
CP0372191
|
4-[(3-methoxyphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0042388
|
2-[[(2R)-1-butylpyrrolidin-2-yl]methyl]-4-[(4-chlorophenyl)methyl]pyrido[3,4-d]pyridazin-1-one
Show/Hide
|
C23H27ClN4O
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0056746
|
8-[(4-chlorophenyl)methyl]-6-[[(2R)-1-(2-methoxyethyl)pyrrolidin-2-yl]methyl]pyrido[2,3-d]pyridazin-5-one
Show/Hide
|
C22H25ClN4O2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0148522
|
6-[[(2R)-1-butylpyrrolidin-2-yl]methyl]-8-[(4-chlorophenyl)methyl]pyrido[2,3-d]pyridazin-5-one
Show/Hide
|
C23H27ClN4O
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0148523
|
8-[(4-chlorophenyl)methyl]-6-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrazino[2,3-d]pyridazin-5-one
Show/Hide
|
C19H20ClN5O
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0179680
|
5-[(4-chlorophenyl)methyl]-7-[[(2R)-1-(2-methoxyethyl)pyrrolidin-2-yl]methyl]pyrido[2,3-d]pyridazin-8-one
Show/Hide
|
C22H25ClN4O2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0339444
|
4-[(4-chlorophenyl)methyl]-2-[[(2R)-1-(2-methoxyethyl)pyrrolidin-2-yl]methyl]pyrido[3,4-d]pyridazin-1-one
Show/Hide
|
C22H25ClN4O2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0339445
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7-[[(2R)-1-butylpyrrolidin-2-yl]methyl]-5-[(4-chlorophenyl)methyl]pyrido[2,3-d]pyridazin-8-one
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C23H27ClN4O
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1
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| 1 |
Ki = 630.96 nM
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CP0428566
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2-methyl-6-(4-piperidin-4-yloxyphenyl)pyridazin-3-one
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C16H19N3O2
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1
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| 1 |
Ki = 695 nM
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CP0484599
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4-(cyclohexylmethyl)-2-[3-(1H-imidazol-4-ylmethyl)phenyl]-4,5-dihydro-1,3-oxazole
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C20H25N3O
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1
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| 1 |
Ki = 707.95 nM
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CP0932426
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1-[4-(4-Styryl-phenoxymethyl)-benzyl]-piperidine oxalate
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C29H31NO5
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1
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| 1 |
Ki = 761 nM
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CP0428264
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3-[4-(3-morpholin-4-ylpropoxy)phenyl]-1H-pyridazin-6-one
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C17H21N3O3
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1
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| 1 |
Ki = 767 nM
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CP0533322
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4-(1H-imidazol-4-ylmethyl)benzonitrile
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C11H9N3
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1
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| 1 |
Ki = 812.83 nM
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CP0922353
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1-[4-(4-Phenethyl-phenoxymethyl)-benzyl]-piperidine oxalate
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C29H33NO5
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1
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| 1 |
Ki = 890 nM
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CP0919133
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1-[4-(2-Chloro-allyl)-piperazin-1-yl]-4-(4-chloro-phenyl)-butane-1,4-dione hydrochloride
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C17H21Cl3N2O2
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1
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| 1 |
Ki = 1100 nM
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CP0508015
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7-[4-[3-[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]propoxy]phenyl]-5-propan-2-ylthieno[2,3-d]pyridazin-4-one
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C24H31N3O3S
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1
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| 1 |
Ki = 1120 nM
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CP0336584
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N-ethyl-N-(3-piperidin-1-ylpropyl)quinolin-4-amine
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C19H27N3
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1
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| 1 |
Ki = 1130 nM
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CP0878032
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1-[4-(4-Pentyl-phenoxymethyl)-benzyl]-piperidine oxalate
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C26H35NO5
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1
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| 1 |
Ki = 1130 nM
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CP0531921
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4-({3-[2-(naphthalen-1-yl)ethynyl]phenyl}methyl)-1H-imidazole
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C22H16N2
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1
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| 1 |
Ki = 1737.8 nM
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CP0428856
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(4-methylpiperidin-1-yl)(6-(3-morpholinopropoxy)naphthalen-2-yl)methanone
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C24H32N2O3
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1
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| 1 |
Ki = 2000 nM
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CP0484792
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2-[4-(1H-imidazol-4-ylmethyl)phenyl]-4,4-dimethyl-4,5-dihydro-1,3-oxazole
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C15H17N3O
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1
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| 1 |
Ki = 2511.89 nM
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CP0526962
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2-[3-(1H-imidazol-4-ylmethyl)phenyl]-5,5-dimethyl-5,6-dihydro-4H-1,3-oxazine
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C16H19N3O
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1
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| 1 |
Ki = 2511.89 nM
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CP0500010
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4-[(4-chlorophenyl)methyl]-2-[(1-methylpyrrolidin-3-yl)methyl]phthalazin-1-one
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C21H22ClN3O
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1
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| 1 |
Ki > 398.11 nM
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CP0513990
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4-[(4-chlorophenyl)methyl]-2-[[(2S)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
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C21H22ClN3O
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1
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| 1 |
Ki > 398.11 nM
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CP0372186
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4-[(4-fluorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
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C21H22FN3O
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1
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| 1 |
Ki > 501.19 nM
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CP0513253
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4-[(4-chlorophenyl)methyl]-2-[2-(dimethylamino)ethyl]phthalazin-1-one
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C19H20ClN3O
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1
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| 1 |
Ki > 501.19 nM
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CP0377782
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4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-3-yl)phthalazin-1-one
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C22H24ClN3O
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1
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| 1 |
Ki > 630.96 nM
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CP0437970
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methyl 4-[[3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-4-oxophthalazin-1-yl]methyl]benzoate
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C23H25N3O3
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1
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| 1 |
Ki > 630.96 nM
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CP0437971
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4-[(3,4-dimethoxyphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
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C23H27N3O3
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1
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| 1 |
Ki > 630.96 nM
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CP0466028
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4-[(3,4-difluorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
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C21H21F2N3O
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1
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| 1 |
Ki > 630.96 nM
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CP0500011
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2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-4-pentylphthalazin-1-one
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C19H27N3O
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1
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| 1 |
Ki > 630.96 nM
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CP0507749
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4-[(4-tert-butylphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
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C25H31N3O
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1
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| 1 |
Ki > 630.96 nM
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CP0520920
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4-[(3-chlorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
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C21H22ClN3O
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1
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| 1 |
Ki > 630.96 nM
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CP0520926
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4-[[3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-4-oxophthalazin-1-yl]methyl]benzoic acid
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C22H23N3O3
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1
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| 1 |
Ki > 630.96 nM
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CP0520928
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4-[(4-methylphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
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C22H25N3O
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1
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| 1 |
Ki > 630.96 nM
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CP0372364
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1-((1H-Imidazol-4-yl)methyl)-4-(4-tert-butylphenyl)-piperazine
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C18H26N4
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1
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| 1 |
Ki > 1000 nM
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CP0388223
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1-((1H-Imidazol-4-yl)methyl)-4-phenylpiperazine
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C14H18N4
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1
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| 1 |
Ki > 1000 nM
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CP0425946
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1-((1H-Imidazol-4-yl)methyl)-4-(4-trifluoromethylphenyl)-piperazine
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C15H17F3N4
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1
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| 1 |
Ki > 1000 nM
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CP0470832
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1-[(1R,2R)-2-(6-chloro-1H-benzimidazol-2-yl)cyclopropyl]-N-[(4-chlorophenyl)methyl]methanamine
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C18H17Cl2N3
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1
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| 1 |
Ki > 1000 nM
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CP0481809
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1-[(1R,2S)-2-(5-chloro-1H-indol-2-yl)cyclopropyl]-N-[(4-chlorophenyl)methyl]methanamine
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C19H18Cl2N2
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1
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| 1 |
Ki > 1000 nM
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CP0481810
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2-[(1S,2S)-2-(5-chloro-1H-indol-2-yl)cyclopropyl]-N-[(4-chlorophenyl)methyl]ethanamine
Show/Hide
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C20H20Cl2N2
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1
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| 1 |
Ki > 1000 nM
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CP0492070
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2-[(1S,2R)-2-(6-chloro-1H-benzimidazol-2-yl)cyclopropyl]-N-[(4-chlorophenyl)methyl]ethanamine
Show/Hide
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C19H19Cl2N3
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1
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| 1 |
Ki > 1000 nM
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CP0532518
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N-[(4-chlorophenyl)methyl]-2-[(1S,2R)-2-(4-methylpiperazin-1-yl)cyclopropyl]ethanamine
Show/Hide
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C17H26ClN3
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1
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| 1 |
Ki > 1000 nM
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CP0534664
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N-[(4-chlorophenyl)methyl]-1-[(1R,2R)-2-(4-methylpiperazin-1-yl)cyclopropyl]methanamine
Show/Hide
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C16H24ClN3
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1
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| 1 |
Ki > 1000 nM
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CP0557339
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N-[(4-chlorophenyl)methyl]-2-[(1S,2R)-2-piperazin-1-ylcyclopropyl]ethanamine
Show/Hide
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C16H24ClN3
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1
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| 1 |
Ki > 1000 nM
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CP0578830
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N-[(4-chlorophenyl)methyl]-1-[(1R,2R)-2-piperazin-1-ylcyclopropyl]methanamine
Show/Hide
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C15H22ClN3
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1
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| 1 |
Ki > 1000 nM
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CP0479055
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2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-4-(2-phenylethyl)phthalazin-1-one
Show/Hide
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C22H25N3O
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1
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| 1 |
Ki > 1995.26 nM
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CP0417290
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1'-cyclobutylspiro[3,4-dihydrochromene-2,4'-piperidine]-6-ol
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C17H23NO2
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1
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| 1 |
Ki > 3000 nM
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