Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(1H-imidazol-4-ylmethyl)piperidine
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 PubChem ID
CID: 3035842
SID: 136949843
Canonical SMILES
C(C1CCNCC1)c1cnc[nH]1
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Compound Formula C9H15N3
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 0.67 nM
   TI
   LI
   LO
   TS
2
Ki = 0.3 nM
   TI
   LI
   LO
   TS
3
Ki = 0.4074 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 0.67 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 0.5012 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 0.03981 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.1259 nM
   TI
   LI
   LO
   TS
3
EC50 = 0.1318 nM
   TI
   LI
   LO
   TS
4
Ki = 0.4786 nM
   TI
   LI
   LO
   TS
5
Ki = 0.5012 nM
   TI
   LI
   LO
   TS