Brief Information of the Compound and Protein
Compound Name
Trans-4,4-dimethyl-2-(4-(3-(piperidin-1-yl)cyclobutoxy)phenyl)-4,5-dihydrooxazole
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Canonical SMILES
CC1(C)COC(c2ccc(O[C@H]3C[C@H](N4CCCCC4)C3)cc2)=N1
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Compound Formula C20H28N2O2
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 0.631 nM
   TI
   LI
   LO
   TS
2
Ki = 7.943 nM
   TI
   LI
   LO
   TS