Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-[(4-chlorophenyl)methyl]-6-[[(2R)-1-(2-methoxyethyl)pyrrolidin-2-yl]methyl]pyrido[2,3-d]pyridazin-5-one
    Show/Hide
 PubChem ID
CID: 71458205
SID: 163439818
Canonical SMILES
COCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ncccc2c1=O
    Show/Hide
Compound Formula C22H25ClN4O2
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 630.96 nM
   TI
   LI
   LO
   TS