Brief Information of the Compound and Protein
Compound Name
N-cyclohexyl-6-(1-propan-2-ylpiperidin-4-yl)oxynaphthalene-2-carboxamide
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PubChem ID
CID: 44578637
Canonical SMILES
CC(C)N1CCC(CC1)Oc1ccc2cc(ccc2c1)C(=O)NC1CCCCC1
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Compound Formula C25H34N2O2
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
2
Ki = 87 nM
   TI
   LI
   LO
   TS