Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole
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 PubChem ID
CID: 46222048
SID: 96076719
Canonical SMILES
CC(C)(C)c1ccc(SCCc2cnc[nH]2)cc1
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Compound Formula C15H20N2S
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 0.75 nM
   TI
   LI
   LO
   TS
2
Ki = 0.17 nM
   TI
   LI
   LO
   TS
3
Ki = 0.43 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 0.75 nM
   TI
   LI
   LO
   TS