Brief Information of the Compound and Protein
Compound Name
(R)-4-(1-(1H-Imidazol-4-yl)-2-(4-(trifluoromethyl)phenylthio)ethyl)piperidine
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PubChem ID
CID: 46929648
SID: 99435592
Canonical SMILES
FC(F)(F)c1ccc(SC[C@H](C2CCNCC2)c2cnc[nH]2)cc1
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Compound Formula C17H20F3N3S
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 74 nM
   TI
   LI
   LO
   TS
2
Ki = 180 nM
   TI
   LI
   LO
   TS