Brief Information of the Compound and Protein
Compound Name
4-(1H-imidazol-5-ylmethyl)pyridine
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PubChem ID
CID: 9989505
SID: 16435196
Canonical SMILES
C(c1cnc[nH]1)c1ccncc1
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Compound Formula C9H9N3
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
EC50 = 1.1 nM
   TI
   LI
   LO
   TS
2
Ki = 0.77 nM
   TI
   LI
   LO
   TS
3
Ki = 0.7943 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC Homo sapiens (Human)  4
1
EC50 = 0.1585 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.182 nM
   TI
   LI
   LO
   TS
3
Ki = 0.7943 nM
   TI
   LI
   LO
   TS
4
Ki = 0.8511 nM
   TI
   LI
   LO
   TS