| Compound ID |
Compound Name |
Compound Formula |
|
CP0571033
|
(7R,11S)-11-(3,3-difluorobutyl)-8-ethyl-7-methyl-14,17-dioxa-5,8,10,19,20,25-hexazatetracyclo[16.6.1.12,6.019,23]hexacosa-1(24),2(26),3,5,18(25),20,22-heptaen-9-one
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|
C25H32F2N6O3
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0544795
|
(7R,11S)-11-(3,3-difluorobutyl)-8-ethyl-3-methoxy-7-methyl-14,17-dioxa-5,8,10,19,20,25-hexazatetracyclo[16.6.1.12,6.019,23]hexacosa-1(24),2(26),3,5,18(25),20,22-heptaen-9-one
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|
C26H34F2N6O4
|
1
|
| 1 |
EC50 = 0.25 nM
|
|
|
|
CP0580109
|
(7R,11S)-8-ethyl-3-methoxy-7,11-dimethylspiro[17-oxa-5,8,10,20,23,25-hexazatetracyclo[16.6.1.12,6.019,23]hexacosa-1(24),2(26),3,5,18(25),19,21-heptaene-15,4'-oxane]-9-one
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|
C28H38N6O4
|
1
|
| 1 |
EC50 = 0.29 nM
|
|
|
|
CP0575836
|
(7R,11R)-8-ethyl-3-methoxy-7-methyl-11-(2-methyl-1,3-thiazol-5-yl)-17-oxa-5,8,10,20,23,25-hexazatetracyclo[16.6.1.12,6.019,23]hexacosa-1(24),2(26),3,5,18(25),19,21-heptaen-9-one
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|
C27H33N7O3S
|
1
|
| 1 |
EC50 = 0.37 nM
|
|
|
|
CP0579832
|
(7R,11S)-11-(3,3-difluorobutyl)-8-ethyl-3-methoxy-7-methyl-13,17-dioxa-5,8,10,19,20,25-hexazatetracyclo[16.6.1.12,6.019,23]hexacosa-1(24),2(26),3,5,18(25),20,22-heptaen-9-one
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|
C26H34F2N6O4
|
1
|
| 1 |
EC50 = 0.43 nM
|
|
|
|
CP0576059
|
(7R,11S)-8-ethyl-3-methoxy-7-methyl-11-(3,3,3-trifluoropropyl)-14,17-dioxa-5,8,10,19,20,25-hexazatetracyclo[16.6.1.12,6.019,23]hexacosa-1(24),2(26),3,5,18(25),20,22-heptaen-9-one
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|
C25H31F3N6O4
|
1
|
| 1 |
EC50 = 0.47 nM
|
|
|
|
CP0562627
|
1-ethyl-3-[(2S)-1,1,1,5,5,5-hexafluoropentan-2-yl]-1-[(1R)-1-[5-methoxy-4-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)pyridin-2-yl]ethyl]urea
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|
C23H26F6N6O3
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0562626
|
1-[(1R)-1-[3-(3-chloro-8-methoxyimidazo[1,2-a]pyridin-6-yl)phenyl]ethyl]-1-ethyl-3-[(2S)-1,1,1,5,5,5-hexafluoropentan-2-yl]urea
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|
C24H25ClF6N4O2
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0574614
|
3-[(3R)-1-(cyanomethyl)piperidin-3-yl]-1-ethyl-1-[(1R)-1-[3-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)phenyl]ethyl]urea
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|
C25H31N7O2
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0562625
|
3-[(1R)-1-(4,4-difluorooxan-2-yl)propyl]-1-ethyl-1-[(1R)-1-[3-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)phenyl]ethyl]urea
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|
C26H33F2N5O3
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0542743
|
3-[(1S)-1-(3,3-difluorocyclohexyl)-2,2,2-trifluoroethyl]-1-ethyl-1-[(1R)-1-[3-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)phenyl]ethyl]urea
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|
C26H30F5N5O2
|
1
|
| 1 |
EC50 = 0.9 nM
|
|
|
|
CP0576490
|
US11098029, Example 24
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|
C21H31FN2O5S
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0578871
|
1-ethyl-1-[(1R)-1-[3-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)phenyl]ethyl]-3-[1,1,1-trifluoro-3-(triazol-2-yl)propan-2-yl]urea
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|
C23H25F3N8O2
|
1
|
| 1 |
EC50 = 2.8 nM
|
|
|
|
CP0568038
|
1-ethyl-3-[(2S)-1,1,1,5,5,5-hexafluoropentan-2-yl]-1-[2,2,2-trifluoro-1-[5-methoxy-4-(8-methoxyimidazo[1,2-b]pyridazin-6-yl)pyridin-2-yl]ethyl]urea
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|
C23H23F9N6O3
|
1
|
| 1 |
EC50 = 4.7 nM
|
|
|
|
CP0574205
|
N-[2-[3-[[5-[3-(dimethylcarbamoyl)phenyl]-2-methoxyphenyl]sulfonylamino]phenyl]ethyl]-2-(triazol-2-yl)benzamide
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|
C33H32N6O5S
|
1
|
| 1 |
EC50 = 5.248 nM
|
|
|
|
CP0569039
|
1-ethyl-3-[(2S)-1,1,1,5,5,5-hexafluoropentan-2-yl]-1-[(1R)-1-(3-imidazo[1,2-a]pyridin-6-ylphenyl)ethyl]urea
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|
C23H24F6N4O
|
1
|
| 1 |
EC50 = 7.1 nM
|
|
|
|
CP0544221
|
1-[2,2-difluoro-1-[5-methoxy-4-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)pyridin-2-yl]propyl]-1-ethyl-3-[(3R)-1,1,1-trifluoropentan-3-yl]urea
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|
C24H29F5N6O3
|
1
|
| 1 |
EC50 = 8.1 nM
|
|
|
|
CP0579696
|
3-[4-methoxy-3-[[8-[(3-methoxybenzoyl)amino]-7-methylnaphthalen-2-yl]sulfamoyl]phenyl]-N,N-dimethylbenzamide
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|
C35H33N3O6S
|
1
|
| 1 |
EC50 = 9.21 nM
|
|
|
|
CP0571761
|
1-ethyl-3-[(2S)-1,1,1,5,5,5-hexafluoropentan-2-yl]-1-[(1R)-1-[5-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)-1-methyl-6-oxopyridin-3-yl]ethyl]urea
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|
C23H26F6N6O3
|
1
|
| 1 |
EC50 = 10.5 nM
|
|
|
|
CP0575730
|
3-[4-methoxy-3-[[8-[(3-methoxybenzoyl)-methylamino]naphthalen-2-yl]sulfamoyl]phenyl]-N,N-dimethylbenzamide
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|
C35H33N3O6S
|
1
|
| 1 |
EC50 = 22.7 nM
|
|
|
|
CP0546362
|
3-[4-methoxy-3-[[8-[(3-methoxybenzoyl)amino]naphthalen-2-yl]sulfamoyl]phenyl]-N,N-dimethylbenzamide
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|
C34H31N3O6S
|
1
|
| 1 |
EC50 = 24.3 nM
|
|
|
|
CP0576230
|
1-ethyl-3-[(2S)-1,1,1,5,5,5-hexafluoropentan-2-yl]-1-[(1S)-2,2,2-trifluoro-1-[5-methoxy-4-(7-methoxy-3-methylbenzimidazol-5-yl)pyridin-2-yl]ethyl]urea
Show/Hide
|
C25H26F9N5O3
|
1
|
| 1 |
EC50 = 29.8 nM
|
|
|
|
CP0568564
|
3-[4-methoxy-3-[[8-[(3-methoxybenzoyl)-methylamino]-7-methylnaphthalen-2-yl]sulfamoyl]phenyl]-N,N-dimethylbenzamide
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|
C36H35N3O6S
|
1
|
| 1 |
EC50 = 31.1 nM
|
|
|
|
CP0568032
|
1-ethyl-1-[(1S)-2,2,2-trifluoro-1-[5-methoxy-4-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)pyridin-2-yl]ethyl]-3-[1-(trifluoromethyl)cyclobutyl]urea
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|
C23H24F6N6O3
|
1
|
| 1 |
EC50 = 45.8 nM
|
|
|
|
CP0571657
|
3-[4-methoxy-3-[[8-[(4-methoxybenzoyl)-methylamino]naphthalen-2-yl]sulfamoyl]phenyl]-N,N-dimethylbenzamide
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|
C35H33N3O6S
|
1
|
| 1 |
EC50 = 51.1 nM
|
|
|
|
CP0571007
|
1-ethyl-1-[(1R)-1-[3-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)phenyl]ethyl]-3-[[(3S)-5-oxomorpholin-3-yl]methyl]urea
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|
C23H28N6O4
|
1
|
| 1 |
EC50 = 192.9 nM
|
|
|
|
CP0548118
|
3-[3-[(8-benzamidonaphthalen-2-yl)sulfamoyl]-4-methoxyphenyl]-N,N-dimethylbenzamide
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|
C33H29N3O5S
|
1
|
| 1 |
EC50 = 873 nM
|
|
|
|
CP0580054
|
1-ethyl-3-[(2S)-1,1,1,5,5,5-hexafluoropentan-2-yl]-1-[1-[2-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)pyrimidin-4-yl]ethyl]urea
Show/Hide
|
C21H23F6N7O2
|
1
|
| 1 |
EC50 = 1058 nM
|
|
|
|
CP0569538
|
3-[3-[[8-[benzoyl(methyl)amino]naphthalen-2-yl]sulfamoyl]-4-methoxyphenyl]-N,N-dimethylbenzamide
Show/Hide
|
C34H31N3O5S
|
1
|
| 1 |
EC50 = 1949 nM
|
|
|
|
CP0544594
|
3-[3-[(7-benzamidonaphthalen-2-yl)sulfamoyl]-4-methoxyphenyl]-N,N-dimethylbenzamide
Show/Hide
|
C33H29N3O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0545034
|
3-[3-[[7-[benzoyl(methyl)amino]naphthalen-2-yl]sulfamoyl]-4-methoxyphenyl]-N,N-dimethylbenzamide
Show/Hide
|
C34H31N3O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0569492
|
N-[7-[[5-[3-(dimethylcarbamoyl)phenyl]-2-methoxyphenyl]sulfonylamino]naphthalen-1-yl]-2-methoxy-N-methylbenzamide
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|
C35H33N3O6S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0462693
|
1-(3,4-dichlorophenyl)-2-[2-imino-3-[(4-methylphenyl)methyl]benzimidazol-1-yl]ethanol
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|
C23H21Cl2N3O
|
1
|
| 1 |
EC50 > 3200 nM
|
|
|
|
CP0551747
|
N-(13-methyl-11-oxo-7,10,18-trioxa-12,24-diazatetracyclo[17.2.2.12,6.012,16]tetracosa-2(24),3,5-trien-15-yl)methanesulfonamide
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|
C21H31N3O6S
|
1
|
| 1 |
IC50 = 0.04 nM
|
|
|
|
CP0579743
|
N-(14-methyl-12-oxo-7,11,19-trioxa-13,25-diazatetracyclo[18.2.2.12,6.013,17]pentacosa-2(25),3,5-trien-16-yl)methanesulfonamide
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|
C22H33N3O6S
|
1
|
| 1 |
IC50 = 0.05 nM
|
|
|
|
CP0571347
|
N-(3,5-difluoro-13-methyl-11-oxo-7,10,18-trioxa-12,24-diazatetracyclo[17.2.2.12,6.012,16]tetracosa-2(24),3,5-trien-15-yl)methanesulfonamide
Show/Hide
|
C21H29F2N3O6S
|
1
|
| 1 |
IC50 = 0.07 nM
|
|
|
|
CP0579457
|
(8E,13R,15S,16R)-15-(dimethylsulfamoylamino)-13-methyl-11-oxo-10,18-dioxa-12-azatetracyclo[17.2.2.02,7.012,16]tricosa-2,4,6,8-tetraene
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|
C23H33N3O5S
|
1
|
| 1 |
IC50 = 0.09 nM
|
|
|
|
CP0569907
|
15-(dimethylsulfamoylamino)-13-methyl-11-oxo-7,10,18-trioxa-12-azatetracyclo[17.2.2.12,6.012,16]tetracosa-2(24),3,5-triene
Show/Hide
|
C23H35N3O6S
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0579744
|
N-(3,13-dimethyl-11-oxo-7,10,18-trioxa-12,24-diazatetracyclo[17.2.2.12,6.012,16]tetracosa-2,4,6(24)-trien-15-yl)methanesulfonamide
Show/Hide
|
C22H33N3O6S
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0326222
|
[(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H23ClN6O2
|
5
|
| 1 |
IC50 = 0.4 nM
|
|
|
| 2 |
IC50 = 56 nM
|
|
|
| 3 |
Ki = 0.35 nM
|
|
|
| 4 |
Ki = 0.4 nM
|
|
|
| 5 |
Ki = 11.8 nM
|
|
|
|
CP0517471
|
N-[[(2S)-5-fluoro-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
|
C26H24FN3O3S
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0867328
|
rac-N-((1-(5-(4-fluorophenyl)-2-methylthiazole-4-carbonyl)piperidin-2-yl)methyl)benzofuran-4-carboxamide
Show/Hide
|
C26H24FN3O3S
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0458629
|
(2R)-2-[(8S)-1-chloro-8-[2-[4-(difluoromethoxy)phenyl]ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H29ClF2N4O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0749809
|
(rac)-(7-(3,4-dimethoxybenzyl)-4,5-dihydrothieno[2,3-c]pyridin-6(7H)-yl)(1-ethyl-1H-indol-3-yl)methanone
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|
C27H28N2O3S
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0511741
|
N-ethyl-N-[(2S)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C23H24FN7O
|
1
|
| 1 |
IC50 = 1.61 nM
|
|
|
|
CP0955590
|
(S)-(2-(3-chloro-4-methoxybenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
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|
C24H25ClN2O2S
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0450685
|
N-[[1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
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|
C29H27N3O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0549104
|
N-[[(2S)-5,5-difluoro-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C29H25F2N3O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0455954
|
(2R)-2-[(8S)-1-chloro-3-cyclopropyl-8-[2-[4-(difluoromethoxy)-3-fluorophenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H28ClF3N4O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0523012
|
6-(2,6-dimethoxyphenyl)-1-[[3-(2-methyl-1,3-thiazol-4-yl)phenyl]methyl]piperidin-2-one
Show/Hide
|
C24H26N2O3S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0349347
|
US9242970, 367
Show/Hide
|
C25H22FNO4
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0530463
|
US9242970, 406
Show/Hide
|
C24H19F2NO3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0430613
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H23FN8O
|
1
|
| 1 |
IC50 = 2.57 nM
|
|
|
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CP0478340
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C23H23FN6O2
|
1
|
| 1 |
IC50 = 2.73 nM
|
|
|
|
CP0403779
|
N-ethyl-N-[2-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H22FN7O
|
1
|
| 1 |
IC50 = 2.81 nM
|
|
|
|
CP0497677
|
2-(N-(2-chloro-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N-ethyl-N-(5-methylpyrazin-2-yl)acetamide
Show/Hide
|
C25H30ClN5O5S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
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CP0381238
|
(R)-2-((S)-1-ethyl-4-(4-ethylphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0501338
|
(R)-2-((S)-1-ethyl-3-methyl-4-(4-(trifluoromethyl)phenethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C27H31F3N4O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0433078
|
1-(dibenzofuran-2-ylmethyl)-6-(2,4-dimethoxypyridin-3-yl)piperidin-2-one
Show/Hide
|
C25H24N2O4
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0099206
|
US9242970, 412
Show/Hide
|
C24H20FNO4
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0958947
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C25H28N2O3S
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0390759
|
4-(3,4-dimethoxyphenyl)sulfonyl-6-fluoro-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C22H26FN3O6S
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0860065
|
(rac)-(2-(3,4-dimethoxybenzyl)piperidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
Show/Hide
|
C24H28N4O3
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0853721
|
(S)-(2-(2H-1,2,3-triazol-2-yl)phenyl)(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)methanone
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0384535
|
2-(N-(2-chloro-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N-(1,5-dimethyl-1H-pyrazol-3-yl)-N-ethylacetamide
Show/Hide
|
C25H32ClN5O5S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0525953
|
2-(N-(2-cyano-4-methylphenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C22H27N3O5S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
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CP0542401
|
N-[[1-(2-methyl-4-phenyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
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C26H25N3O3S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0473217
|
(2R)-2-[(8R)-1-chloro-3-ethyl-8-[[3-(trifluoromethyl)phenoxy]methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C25H26ClF3N4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0444292
|
1-(dibenzofuran-2-ylmethyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one
Show/Hide
|
C26H25NO4
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0260680
|
US9242970, 357
Show/Hide
|
C25H23NO5
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
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CP0860201
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(3-(m-tolyl)pyrazin-2-yl)methanone
Show/Hide
|
C25H27N3O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0899802
|
(S)-(2-(3,5-dimethoxybenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C25H28N2O3S
|
1
|
| 1 |
IC50 = 4.3 nM
|
|
|
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CP0492690
|
2-(N-(6-chloro-3-methylbenzo[d]isothiazol-5-yl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C22H26ClN3O5S2
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0923118
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(2-(pyrimidin-2-yl)phenyl)methanone
Show/Hide
|
C24H25N3O3
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
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CP0403090
|
2-(N-(2-chloro-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N-ethyl-N-(6-methylpyridin-2-yl)acetamide
Show/Hide
|
C26H31ClN4O5S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
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CP0407771
|
2-(N-(6-chloro-3-methylbenzo[d]isothiazol-5-yl)-3,4-dimethoxyphenylsulfonamido)-N-ethyl-N-(pyridin-2-yl)acetamide
Show/Hide
|
C25H25ClN4O5S2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
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CP0474343
|
2-(N-(2-chloro-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C22H30ClN3O5S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
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CP0554114
|
2-(4-tert-butyl-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C23H32N2O3S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
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CP0449744
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-(2,3,4-trifluorophenyl)ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C25H26ClF3N4O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0099204
|
US9242970, 408
Show/Hide
|
C24H19ClFNO3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0257370
|
US9242970, 369
Show/Hide
|
C25H22ClNO4
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
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CP0367356
|
(3R)-1-(dibenzofuran-2-ylmethyl)-5-(2-fluoro-6-methoxyphenyl)-3-hydroxypyrrolidin-2-one
Show/Hide
|
C24H20FNO4
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0475352
|
N-[(2S)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H22FN7O
|
1
|
| 1 |
IC50 = 5.68 nM
|
|
|
|
CP0511738
|
N-ethyl-N-[(2S)-1-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C23H24FN7O
|
1
|
| 1 |
IC50 = 5.87 nM
|
|
|
|
CP0390058
|
2-(1-ethyl-3-methyl-4-(4-methylphenethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C27H34N4O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0481622
|
6-(2,4-dimethoxypyridin-3-yl)-1-[(2-phenyl-1,3-thiazol-4-yl)methyl]piperidin-2-one
Show/Hide
|
C22H23N3O3S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0510521
|
6-(2,6-dimethoxyphenyl)-1-[(2-phenyl-1,3-thiazol-4-yl)methyl]piperidin-2-one
Show/Hide
|
C23H24N2O3S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0950972
|
(S)-(5-(3-chlorophenyl)-2-methylthiazol-4-yl)(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)methanone
Show/Hide
|
C24H25ClN2O3S
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
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CP0459005
|
(4-chlorophenyl)-[(3R,5S)-3,5-dimethyl-7-methylsulfanyl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methanone
Show/Hide
|
C19H20ClNO2S
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
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CP0847456
|
(S)-(5-(benzo[d][1,3]dioxol-5-yl)-2-methylthiazol-4-yl)(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)methanone
Show/Hide
|
C25H26N2O5S
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
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CP0403091
|
2-(N-(2-chloro-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N-ethyl-N-(1-methyl-1H-pyrazol-3-yl)acetamide
Show/Hide
|
C24H30ClN5O5S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
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CP0517460
|
2-(N-(6-chloro-3-methylbenzo[d]isothiazol-5-yl)-3,4-dimethoxyphenylsulfonamido)-N-ethyl-N-(6-methylpyridin-2-yl)acetamide
Show/Hide
|
C26H27ClN4O5S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
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CP0460925
|
2-(1-ethyl-3-methyl-4-(3-(trifluoromethyl)phenethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C27H31F3N4O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0435977
|
[(2S)-5-fluoro-2-[[[5-(trifluoromethyl)pyridin-2-yl]amino]methyl]piperidin-1-yl]-(2-methyl-5-phenyl-1,3-thiazol-4-yl)methanone
Show/Hide
|
C23H22F4N4OS
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0375625
|
(2R)-2-[(8S)-1-chloro-3-cyclopropyl-8-[2-[3-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H28ClF3N4O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0407633
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[3-fluoro-4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27ClF4N4O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0874293
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(5-(3-methoxyphenyl)-2-methylthiazol-4-yl)methanone
Show/Hide
|
C25H28N2O4S
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0503013
|
2-(N-(2-chloro-5-methylphenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C21H27ClN2O5S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0385542
|
N-[[1-(2-methyl-4-phenyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C27H26N4O2S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0416076
|
N-[[(2S,6S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]-6-methylpiperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
|
C27H26FN3O3S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0513535
|
(2-methyl-4-phenyl-1,3-thiazol-5-yl)-[2-[[[5-(trifluoromethyl)pyridin-2-yl]amino]methyl]piperidin-1-yl]methanone
Show/Hide
|
C23H23F3N4OS
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0087584
|
(2R)-2-[(1S)-6,7-dimethoxy-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-3,4-dihydro-1H-isoquinolin-2-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C29H31F3N2O3
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
Ki = 4.7 nM
|
|
|
|
CP0500846
|
(2R)-2-[(8S)-1-chloro-8-[2-[3,5-difluoro-4-(trifluoromethyl)phenyl]ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H26ClF5N4O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0420708
|
6-(2,6-dimethoxyphenyl)-1-[(3-pyridin-2-ylphenyl)methyl]piperidin-2-one
Show/Hide
|
C25H26N2O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0847455
|
(S)-(5-(2,3-dihydrobenzofuran-5-yl)-2-methylthiazol-4-yl)(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)methanone
Show/Hide
|
C26H28N2O4S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0860066
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
Show/Hide
|
C23H26N4O3
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0450686
|
N-[[(2S,3R)-3-methyl-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
|
C27H27N3O3S
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0464870
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-5-methyl-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C25H24FN5O2
|
1
|
| 1 |
IC50 = 8.85 nM
|
|
|
|
CP0501697
|
(R)-2-((S)-1-ethyl-4-(4-isopropylphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0375627
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28ClF3N4O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0455955
|
(2R)-2-[(8S)-1-chloro-3-cyclopropyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H28ClF3N4O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0375881
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[2-fluoro-3-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27ClF4N4O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0404372
|
(2R)-2-[(8R)-1-chloro-3-ethyl-8-[[4-(trifluoromethyl)phenoxy]methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C25H26ClF3N4O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0420706
|
1-(dibenzofuran-2-ylmethyl)-5-(2,6-dimethoxyphenyl)-3-methylpyrrolidin-2-one
Show/Hide
|
C26H25NO4
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0444291
|
6-(2,6-dimethoxyphenyl)-1-[[2-(1,3-thiazol-2-yl)pyridin-4-yl]methyl]piperidin-2-one
Show/Hide
|
C22H23N3O3S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0502219
|
2-(N-(2-cyano-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C23H30N4O5S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0401810
|
2-(1-ethyl-4-(3-fluorophenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C26H31FN4O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0385827
|
(2R)-2-[1-cyano-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H28F3N5O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0404370
|
(2R)-2-[(8S)-1-chloro-3-cyclopropyl-8-[2-[3-fluoro-4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H27ClF4N4O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0469076
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[3-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28ClF3N4O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0899804
|
(S)-(2-(3-chloro-4-methylbenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C24H25ClN2OS
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0899806
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(5-(4-methoxyphenyl)-2-methylthiazol-4-yl)methanone
Show/Hide
|
C25H28N2O4S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0415021
|
(2R)-2-[(8S)-1-chloro-3-propan-2-yl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H30ClF3N4O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0474053
|
(2R)-2-[(8S)-3-ethyl-1-(trifluoromethyl)-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H28F6N4O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0430614
|
N-ethyl-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H22FN7O2
|
1
|
| 1 |
IC50 = 11.3 nM
|
|
|
|
CP0478339
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H21FN6O2
|
1
|
| 1 |
IC50 = 11.6 nM
|
|
|
|
CP0429279
|
N-[2-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H20FN7O
|
1
|
| 1 |
IC50 = 11.9 nM
|
|
|
|
CP0501339
|
2-(4-(4-chlorophenethyl)-1-ethyl-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C26H31ClN4O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0449763
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[2-fluoro-4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27ClF4N4O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0481531
|
6-(2,6-dimethoxyphenyl)-1-[(2-methyl-1,3-benzothiazol-5-yl)methyl]piperidin-2-one
Show/Hide
|
C22H24N2O3S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0899808
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(2-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl)methanone
Show/Hide
|
C23H25N3O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0472561
|
US9828368, Example 27
Show/Hide
|
C22H30N2O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0472558
|
[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)-5-methyl-1,3-oxazol-2-yl]-2-methylpiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H27N5O3
|
1
|
| 1 |
IC50 = 12.8 nM
|
|
|
|
CP0415412
|
N-[[(2S)-5-hydroxy-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C29H27N3O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0514118
|
(2R)-2-[(8S)-1-chloro-3-methyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C25H26ClF3N4O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0379054
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-5-(5-methylpyridin-3-yl)-2-phenylpyridine-3-carboxamide
Show/Hide
|
C26H24N4O3
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
Ki = 0.3 nM
|
|
|
|
CP0415023
|
(2R)-2-[(8S)-3-ethyl-1-methylsulfanyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H31F3N4OS
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0500845
|
(2R)-2-[(8S)-1-chloro-8-[2-[2,3-difluoro-4-(trifluoromethyl)phenyl]ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H26ClF5N4O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0480713
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-5-(5-methylpyridin-3-yl)-2-phenylbenzamide
Show/Hide
|
C27H25N3O3
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
Ki = 0.3 nM
|
|
|
|
CP0395535
|
N-ethyl-N-[2-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H22FN7O
|
1
|
| 1 |
IC50 = 14.2 nM
|
|
|
|
CP0461652
|
(2R)-2-[(8S)-1-chloro-8-[2-(4-cyanophenyl)ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28ClN5O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0488938
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[4-fluoro-3-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27ClF4N4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0433056
|
2-(2,6-dimethoxyphenyl)-3-[[4-(trifluoromethoxy)phenyl]methyl]-1,3-thiazolidin-4-one
Show/Hide
|
C19H18F3NO4S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0064716
|
US8592457, 7-5
Show/Hide
|
C23H21N5O3S
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
Ki = 1.1 nM
|
|
|
|
CP0411242
|
US8592457, 1-16
Show/Hide
|
C26H23FN4O3
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
Ki = 0.9 nM
|
|
|
|
CP0860200
|
(S)-(2-(2-chloro-3-methoxybenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C24H25ClN2O2S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0930265
|
(rac)-(2-(3,4-dimethoxyphenethyl)piperidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
Show/Hide
|
C25H30N4O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0433393
|
(2R)-2-[(8S)-1-chloro-8-[2-[2,5-difluoro-4-(trifluoromethyl)phenyl]ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H26ClF5N4O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0425199
|
N-ethyl-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)tetrazol-2-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H22FN9O
|
1
|
| 1 |
IC50 = 17.9 nM
|
|
|
|
CP0406197
|
2-{(5R)-5-Methyl-4-[2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}quinazoline
Show/Hide
|
C23H23N7O
|
2
|
| 1 |
IC50 = 18 nM
|
|
|
| 2 |
Ki = 0.47 nM
|
|
|
|
CP0471509
|
(2R)-2-[(8S)-1-chloro-8-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27Cl2F3N4O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0488939
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[4-(trifluoromethoxy)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28ClF3N4O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0874292
|
(S)-(2-(2-chloro-5-methoxybenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C24H25ClN2O2S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0517188
|
(4-(2H-1,2,3-triazol-2-yl)thiophen-3- yl)((2R,5R)-5-(4-((S)-2-hydroxybutan-2- yl)-5-methyloxazol-2-yl)-2- methylpiperidin-1-yl)methanone
Show/Hide
|
C21H27N5O3S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0517212
|
methyl 1-methyl-2-[2-[(3R,6R)-6-methyl-1-[2-(triazol-2-yl)benzoyl]piperidin-3-yl]-1,3-oxazol-4-yl]cyclopropane-1-carboxylate
Show/Hide
|
C24H27N5O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0474340
|
2-(3,4-dimethoxy-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C21H28N2O5S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0401811
|
(R)-2-((R)-1-ethyl-3-methyl-4-(p-tolyloxymethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C26H32N4O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0498935
|
2-(1-ethyl-3-methyl-4-(3-methylphenethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C27H34N4O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0427137
|
6-(2,6-dimethoxyphenyl)-1-[[3-(triazol-2-yl)phenyl]methyl]piperidin-2-one
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0089014
|
US9242970, 260
Show/Hide
|
C20H19F4NO4
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0480150
|
(2R)-2-[1,3-diethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C28H33F3N4O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0403321
|
1-(dibenzofuran-2-ylmethyl)-5-(2,6-dimethoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C25H23NO4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0381233
|
2-(1-ethyl-3-methyl-4-(2-methylphenethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C27H34N4O
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0444288
|
6-(2,6-dimethoxyphenyl)-1-[1-[4-(trifluoromethoxy)phenyl]ethyl]piperidin-2-one
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0088912
|
US8592457, 1-5
Show/Hide
|
C26H24N4O3
|
2
|
| 1 |
IC50 = 21 nM
|
|
|
| 2 |
Ki = 0.5 nM
|
|
|
|
CP0455305
|
N-[(2S)-1-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H22FN7O
|
1
|
| 1 |
IC50 = 21.2 nM
|
|
|
|
CP0429742
|
2-(1-ethyl-4-(2-fluorophenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C26H31FN4O
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0511739
|
N-ethyl-N-[(2S)-1-[4-(5-fluoropyridin-2-yl)triazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H23FN8O
|
1
|
| 1 |
IC50 = 22.8 nM
|
|
|
|
CP0454803
|
N-[[1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C27H25FN4O2S
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0385828
|
(2R)-2-[1-ethenyl-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C28H31F3N4O
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0483778
|
(2R)-2-[3-ethyl-1-iodo-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28F3IN4O
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0389253
|
N-ethyl-5-fluoro-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H20F2N6O2
|
1
|
| 1 |
IC50 = 23.6 nM
|
|
|
|
CP0474052
|
(2R)-2-[3-ethyl-1-methyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H31F3N4O
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0384011
|
2-(1-ethyl-3-methyl-4-(4-(trifluoromethyl)benzyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C26H29F3N4O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0415025
|
(2R)-2-[(8S)-3-ethyl-1-methylsulfonyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H31F3N4O3S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0474074
|
(2R)-2-[(8S)-1-chloro-3-(methoxymethyl)-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28ClF3N4O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0462019
|
6-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0413404
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-5-(2-fluorophenyl)-2-(5-methylpyridin-3-yl)pyridine-4-carboxamide
Show/Hide
|
C26H23FN4O3
|
2
|
| 1 |
IC50 = 25 nM
|
|
|
| 2 |
Ki = 1.4 nM
|
|
|
|
CP0407634
|
(2R)-2-[(8S)-1-chloro-3-cyclopropyl-8-[2-[2-fluoro-4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H27ClF4N4O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0515014
|
[(7R)-4-(5-chloro-4-methylpyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C21H24ClN7O
|
2
|
| 1 |
IC50 = 26 nM
|
|
|
| 2 |
Ki = 6.1 nM
|
|
|
|
CP0071506
|
(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)(4-(quinazolin-2-yl)-1,4-diazepan-1-yl)methanone
Show/Hide
|
C23H23N7O
|
2
|
| 1 |
IC50 = 27 nM
|
|
|
| 2 |
Ki = 0.59 nM
|
|
|
|
CP0380172
|
6-Fluoro-2-{(5R)-5-Methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}quinazoline
Show/Hide
|
C23H22FN7O
|
4
|
| 1 |
IC50 = 27 nM
|
|
|
| 2 |
Ki = 0.17 nM
|
|
|
| 3 |
Ki = 0.2 nM
|
|
|
| 4 |
Ki = 1.8 nM
|
|
|
|
CP0459008
|
(4-chlorophenyl)-[(3R,5S)-7-(difluoromethoxy)-3,5-dimethyl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methanone
Show/Hide
|
C19H18ClF2NO3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0530359
|
[(7R)-7-methyl-4-[4-methyl-5-(trifluoromethyl)pyrimidin-2-yl]-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C21H22F3N7O
|
2
|
| 1 |
IC50 = 27 nM
|
|
|
| 2 |
Ki = 11 nM
|
|
|
|
CP0438828
|
2-{(5R)-5-Methyl-4-[2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}5,6,7,8-tetrahydroquinazoline
Show/Hide
|
C23H27N7O
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
Ki = 0.28 nM
|
|
|
|
CP0433074
|
6-(2,6-dimethoxyphenyl)-1-[(3-phenylphenyl)methyl]piperidin-2-one
Show/Hide
|
C26H27NO3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0481624
|
6-(2,6-dimethoxyphenyl)-1-[(3-pyrimidin-2-ylphenyl)methyl]piperidin-2-one
Show/Hide
|
C24H25N3O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0426829
|
(2R)-2-[(8S)-1-cyclopropyl-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C29H33F3N4O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0510525
|
6-(2,6-dimethoxyphenyl)-1-[(4-phenoxyphenyl)methyl]piperidin-2-one
Show/Hide
|
C26H27NO4
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0406255
|
[(7R)-4-(4-amino-5-methylthieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H24N8OS
|
2
|
| 1 |
IC50 = 29 nM
|
|
|
| 2 |
Ki = 1.2 nM
|
|
|
|
CP0455308
|
N-[(2S)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]butan-2-yl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C23H24FN7O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0416554
|
2-{(5R)-5-Methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}quinazoline
Show/Hide
|
C24H25N7O
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
Ki = 0.36 nM
|
|
|
|
CP0380171
|
[(7R)-4-(4-chloro-5-methylpyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C21H24ClN7O
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
Ki = 3.9 nM
|
|
|
|
CP0411241
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-6-(5-methylpyridin-3-yl)-3-phenylpyrazine-2-carboxamide
Show/Hide
|
C25H23N5O3
|
2
|
| 1 |
IC50 = 31 nM
|
|
|
| 2 |
Ki = 1.4 nM
|
|
|
|
CP0406199
|
6,7-Fluoro-2-{(5R)-5-Methyl-4-[2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}quinazoline
Show/Hide
|
C23H21F2N7O
|
2
|
| 1 |
IC50 = 32 nM
|
|
|
| 2 |
Ki = 0.25 nM
|
|
|
|
CP0523013
|
6-(2,6-dimethoxyphenyl)-1-[(2-phenylpyridin-4-yl)methyl]piperidin-2-one
Show/Hide
|
C25H26N2O3
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0374351
|
[(7R)-4-(4-aminothieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H24N8OS
|
2
|
| 1 |
IC50 = 34 nM
|
|
|
| 2 |
Ki = 0.7 nM
|
|
|
|
CP0382727
|
[(7R)-7-methyl-4-(5-methylfuro[2,3-d]pyrimidin-2-yl)-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H25N7O2
|
2
|
| 1 |
IC50 = 34 nM
|
|
|
| 2 |
Ki = 0.6 nM
|
|
|
|
CP0467192
|
[(7R)-4-(4-amino-6-methylthieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H24N8OS
|
2
|
| 1 |
IC50 = 34 nM
|
|
|
| 2 |
Ki = 1.5 nM
|
|
|
|
CP0385829
|
(2R)-2-[(8S)-1-chloro-3-(cyclopropylmethyl)-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C28H30ClF3N4O
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0427131
|
6-(2,6-dimethoxyphenyl)-1-[(4-propoxyphenyl)methyl]piperidin-2-one
Show/Hide
|
C23H29NO4
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0379841
|
[(7R)-4-(4-amino-6-methylthieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H26N8OS
|
2
|
| 1 |
IC50 = 35 nM
|
|
|
| 2 |
Ki = 0.4 nM
|
|
|
|
CP0406257
|
[(7R)-4-(4-aminothieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C21H22N8OS
|
2
|
| 1 |
IC50 = 35 nM
|
|
|
| 2 |
Ki = 9.2 nM
|
|
|
|
CP0461641
|
[(7R)-7-methyl-4-(5-methylthieno[2,3-d]pyrimidin-2-yl)-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H25N7OS
|
2
|
| 1 |
IC50 = 35 nM
|
|
|
| 2 |
Ki = 0.2 nM
|
|
|
|
CP0398043
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-pyridin-2-ylpyridine-4-carboxamide
Show/Hide
|
C25H23N5O3
|
2
|
| 1 |
IC50 = 36 nM
|
|
|
| 2 |
Ki = 1.4 nM
|
|
|
|
CP0389255
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-5-methyl-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C24H24FN7O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0420711
|
6-(2-ethoxy-6-methoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0379053
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-pyrrolidin-1-ylpyridine-4-carboxamide
Show/Hide
|
C24H27N5O3
|
2
|
| 1 |
IC50 = 37 nM
|
|
|
| 2 |
Ki = 4.5 nM
|
|
|
|
CP0455265
|
3-ethyl-N-methyl-7-[(1R)-2-(methylamino)-2-oxo-1-phenylethyl]-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
Show/Hide
|
C28H32F3N5O2
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0406375
|
[(7R)-4-(4-methoxy-5-methylpyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H27N7O2
|
2
|
| 1 |
IC50 = 38 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
|
CP0899810
|
(S)-(2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C25H26N2O3S
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0415411
|
N-[[(2S,3R)-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)-3-(trifluoromethyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H25F3N4O2S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0470511
|
N-[[(2S,3R)-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)-3-(trifluoromethyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
|
C27H24F3N3O3S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0950971
|
(S)-(2-(benzo[d][1,3]dioxol-5-ylmethyl)pyrrolidin-1-yl)(2-methyl-5-(mtolyl)thiazol-4-yl)methanone
Show/Hide
|
C24H24N2O3S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0485630
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-6-methyl-3-(triazol-2-yl)pyridine-2-carboxamide
Show/Hide
|
C22H22FN7O2
|
1
|
| 1 |
IC50 = 40.5 nM
|
|
|
|
CP0257375
|
US9242970, 261
Show/Hide
|
C20H19ClF3NO4
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0481617
|
6-(2,6-dimethoxyphenyl)-1-[(3-phenoxyphenyl)methyl]piperidin-2-one
Show/Hide
|
C26H27NO4
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0463499
|
[(7R)-4-(5,6-dimethylfuro[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C24H27N7O2
|
2
|
| 1 |
IC50 = 42 nM
|
|
|
| 2 |
Ki = 0.5 nM
|
|
|
|
CP0420703
|
6-(2,6-dimethoxyphenyl)-1-[(6-phenylpyridin-2-yl)methyl]piperidin-2-one
Show/Hide
|
C25H26N2O3
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0374353
|
[(7R)-4-(4-amino-5-methylthieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H26N8OS
|
2
|
| 1 |
IC50 = 43 nM
|
|
|
| 2 |
Ki = 0.3 nM
|
|
|
|
CP0380077
|
[(7R)-4-[4-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H24F3N7O2
|
2
|
| 1 |
IC50 = 43 nM
|
|
|
| 2 |
Ki = 1.5 nM
|
|
|
|
CP0478341
|
N-ethyl-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-5-methyl-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C24H23FN6O2
|
1
|
| 1 |
IC50 = 43.2 nM
|
|
|
|
CP0562004
|
[(7R)-4-[4-methoxy-5-(trifluoromethyl)pyrimidin-2-yl]-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C21H22F3N7O2
|
2
|
| 1 |
IC50 = 44 nM
|
|
|
| 2 |
Ki = 6.3 nM
|
|
|
|
CP0510524
|
6-(2,6-dimethoxyphenyl)-1-(naphthalen-2-ylmethyl)piperidin-2-one
Show/Hide
|
C24H25NO3
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0503025
|
2-(N-(2-chloro-5-(trifluoromethyl)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C21H24ClF3N2O5S
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0513536
|
N-[[(2S,3R)-3-methyl-1-(2-methyl-4-phenyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H28N4O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0531086
|
N-[2-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H20FN7O
|
1
|
| 1 |
IC50 = 51.7 nM
|
|
|
|
CP0384926
|
[(7R)-7-methyl-4-[4-methyl-5-(trifluoromethyl)pyrimidin-2-yl]-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H24F3N7O
|
2
|
| 1 |
IC50 = 52 nM
|
|
|
| 2 |
Ki = 1.6 nM
|
|
|
|
CP0406201
|
2-{(5R)-5-Methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}1,3-benzoxazole
Show/Hide
|
C23H24N6O2
|
2
|
| 1 |
IC50 = 57 nM
|
|
|
| 2 |
Ki = 3.2 nM
|
|
|
|
CP0415927
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-5-(5-fluoropyridin-3-yl)-2-(5-methylpyridin-3-yl)pyridine-4-carboxamide
Show/Hide
|
C25H22FN5O3
|
2
|
| 1 |
IC50 = 57 nM
|
|
|
| 2 |
Ki = 5.2 nM
|
|
|
|
CP0490181
|
N,N-diethyl-2-(4-methyl-N-(2-methylphenyl)sulfonylanilino)acetamide
Show/Hide
|
C20H26N2O3S
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0383668
|
N-[[(2S,3R)-3-methyl-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H28N4O2S
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0458289
|
N-[(2S)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H20FN7O
|
1
|
| 1 |
IC50 = 58.4 nM
|
|
|
|
CP0089015
|
US9242970, 258
Show/Hide
|
C20H20F3NO5
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0403089
|
2-(N-(5-chloro-2-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C22H30ClN3O5S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0422494
|
N,N-diethyl-2-(4-methyl-N-(3-methylphenyl)sulfonylanilino)acetamide
Show/Hide
|
C20H26N2O3S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0415024
|
(2R)-2-[(8S)-1-chloro-3-propyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H30ClF3N4O
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0446902
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H21FN8O
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0450687
|
N-[[(2S,4R)-4-hydroxy-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C29H27N3O3
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0895799
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(5-(4-fluorophenyl)-2-methylthiazol-4-yl)methanone
Show/Hide
|
C24H25FN2O3S
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0519400
|
6-(6-methoxy-2-methyl-1,3-benzoxazol-7-yl)-1-[[3-(2-methyl-1,3-thiazol-4-yl)phenyl]methyl]piperidin-2-one
Show/Hide
|
C25H25N3O3S
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0946756
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(5-methyl-2-(1H-pyrazol-1-yl)phenyl)methanone
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0850591
|
(S)-(2-(3,4-dichlorobenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C23H22Cl2N2OS
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0435431
|
[(7R)-7-methyl-4-(1-methylpyrazolo[3,4-d]pyrimidin-6-yl)-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H25N9O
|
2
|
| 1 |
IC50 = 70 nM
|
|
|
| 2 |
Ki = 49 nM
|
|
|
|
CP0421234
|
2-(N-(3,4-dimethoxyphenyl)sulfonyl-4-methoxyanilino)-N-(1-phenylethyl)acetamide
Show/Hide
|
C25H28N2O6S
|
2
|
| 1 |
IC50 = 70 nM
|
|
|
| 2 |
Ki = 100 nM
|
|
|
|
CP0911563
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(6-methyl-3-(pyrimidin-2-yl)pyridin-2-yl)methanone
Show/Hide
|
C24H26N4O3
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0427138
|
6-(2,6-dimethoxyphenyl)-1-[(4-phenylphenyl)methyl]piperidin-2-one
Show/Hide
|
C26H27NO3
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0447532
|
(2R)-2-[3-ethyl-1-methoxy-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H31F3N4O2
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0475098
|
(4-chlorophenyl)-[(3R,5S)-7-methoxy-3,5-dimethyl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methanone
Show/Hide
|
C19H20ClNO3
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0519407
|
7-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]azepan-2-one
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0433079
|
6-(2,6-dimethoxyphenyl)-1-[(2-pyrazol-1-ylpyridin-4-yl)methyl]piperidin-2-one
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0425198
|
N-ethyl-5-fluoro-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C24H21F2N5O2
|
1
|
| 1 |
IC50 = 80.1 nM
|
|
|
|
CP0542403
|
N-[[(2S,3S)-3-methyl-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H28N4O2S
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0398042
|
5-(azetidin-1-yl)-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)pyridine-4-carboxamide
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 83 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0382726
|
[(7R)-4-(1,3-dimethylpyrazolo[3,4-d]pyrimidin-6-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H27N9O
|
2
|
| 1 |
IC50 = 85 nM
|
|
|
| 2 |
Ki = 3.7 nM
|
|
|
|
CP0420707
|
5-(2,6-dimethoxyphenyl)-4-[[4-(trifluoromethoxy)phenyl]methyl]morpholin-3-one
Show/Hide
|
C20H20F3NO5
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0475652
|
6-fluoro-4-(4-methoxyphenyl)sulfonyl-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C21H24FN3O5S
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0497675
|
N,N-diethyl-2-(N-(4-ethylphenyl)sulfonyl-4-methylanilino)acetamide
Show/Hide
|
C21H28N2O3S
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0474344
|
2-(N-(2-chloro-5-isopropylphenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C23H31ClN2O5S
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0510500
|
6-(6-methoxy-2-methyl-1,3-benzoxazol-7-yl)-1-[(3-phenylphenyl)methyl]piperidin-2-one
Show/Hide
|
C27H26N2O3
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0420709
|
6-(2,6-dimethoxyphenyl)-1-[[3-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0385534
|
[5-(4-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]-[(2S,6S)-2-methyl-6-[[[5-(trifluoromethyl)pyridin-2-yl]amino]methyl]piperidin-1-yl]methanone
Show/Hide
|
C24H24F4N4OS
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0474898
|
[(7R)-4-[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C20H19ClF3N7O
|
2
|
| 1 |
IC50 = 99 nM
|
|
|
| 2 |
Ki = 5.1 nM
|
|
|
|
CP0857706
|
(rac)-(2-(3,4-dimethoxybenzyl)piperidin-1-yl)(1-ethyl-1H-indol-3-yl)methanone
Show/Hide
|
C25H30N2O3
|
1
|
| 1 |
IC50 = 102 nM
|
|
|
|
CP0444257
|
1-[[4-(trifluoromethoxy)phenyl]methyl]-6-(2,4,6-trimethoxyphenyl)piperidin-2-one
Show/Hide
|
C22H24F3NO5
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0422520
|
(2R)-2-[(8R)-1-chloro-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28ClF3N4O
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0378607
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-pyrazin-2-ylpyridine-4-carboxamide
Show/Hide
|
C24H22N6O3
|
2
|
| 1 |
IC50 = 109 nM
|
|
|
| 2 |
Ki = 7.6 nM
|
|
|
|
CP0412313
|
2-(N-(2-cyano-3-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C23H30N4O5S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0415022
|
3-ethyl-N,N-dimethyl-7-[(1R)-2-(methylamino)-2-oxo-1-phenylethyl]-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
Show/Hide
|
C29H34F3N5O2
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0510499
|
(3S,5R)-5-(2,6-dimethoxyphenyl)-3-methyl-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
|
CP0257308
|
US9242970, 264
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
|
CP0389254
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-6-methyl-3-(triazol-2-yl)pyridine-2-carboxamide
Show/Hide
|
C21H22FN9O
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
|
CP0399524
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-phenylpyrimidine-4-carboxamide
Show/Hide
|
C25H23N5O3
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
Ki = 11 nM
|
|
|
|
CP0472642
|
[(7R)-4-[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C21H21ClF3N7O
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
Ki = 0.7 nM
|
|
|
|
CP0444258
|
5-(2,6-dimethoxyphenyl)-3-methyl-1-[(2-methyl-1,3-benzothiazol-5-yl)methyl]pyrrolidin-2-one
Show/Hide
|
C22H24N2O3S
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0489816
|
[(2S,6S)-2-[(1,3-benzoxazol-2-ylamino)methyl]-6-methylpiperidin-1-yl]-[5-(4-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]methanone
Show/Hide
|
C25H25FN4O2S
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0444260
|
US9242970, 259
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0446901
|
N-ethyl-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)tetrazol-2-yl]propan-2-yl]-5-methyl-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C23H23FN8O
|
1
|
| 1 |
IC50 = 129 nM
|
|
|
|
CP0399393
|
6-fluoro-4-(3-methoxyphenyl)sulfonyl-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C21H24FN3O5S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0421239
|
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[[4-(furan-2-ylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C21H18N4O4S2
|
3
|
| 1 |
IC50 = 130 nM
|
|
|
| 2 |
Ki = 200 nM
|
|
|
| 3 |
Ki = 300 nM
|
|
|
|
CP0510520
|
5-(2,6-dimethoxyphenyl)-3-methyl-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 133 nM
|
|
|
|
CP0257369
|
5-(2,6-dimethoxyphenyl)-3,3-difluoro-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C20H18F5NO4
|
1
|
| 1 |
IC50 = 133 nM
|
|
|
|
CP0426712
|
N-[[(2S)-5-(2-hydroxyethylamino)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C31H32N4O3
|
1
|
| 1 |
IC50 = 137 nM
|
|
|
|
CP0503024
|
2-(3-chloro-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C19H23ClN2O3S
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0475353
|
N-ethyl-5-fluoro-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H20F2N8O
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0495985
|
(4-chlorophenyl)-[(3R,5S)-3,5-dimethyl-7-(trifluoromethoxy)-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methanone
Show/Hide
|
C19H17ClF3NO3
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0474341
|
2-(4-bromo-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C19H23BrN2O3S
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0459003
|
(4-chlorophenyl)-[(3R,5S)-3,5,7-trimethyl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methanone
Show/Hide
|
C19H20ClNO2
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0426711
|
N-[[(2S,6S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]-6-methylpiperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H27FN4O2S
|
1
|
| 1 |
IC50 = 151 nM
|
|
|
|
CP0420712
|
6-(2-chloro-6-methoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C20H19ClF3NO3
|
1
|
| 1 |
IC50 = 154 nM
|
|
|
|
CP0379107
|
5-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C20H20F3NO4
|
1
|
| 1 |
IC50 = 158 nM
|
|
|
|
CP0463507
|
(4-chlorophenyl)-[(3R,5S)-7-ethyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methanone
Show/Hide
|
C20H22ClNO2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0379839
|
[(7R)-4-(4-amino-5-methylfuro[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H26N8O2
|
2
|
| 1 |
IC50 = 160 nM
|
|
|
| 2 |
Ki = 5 nM
|
|
|
|
CP0510523
|
6-(2-fluoro-6-methoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C20H19F4NO3
|
1
|
| 1 |
IC50 = 161 nM
|
|
|
|
CP0415926
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-5-(1-methylpyrazol-4-yl)-2-(5-methylpyridin-3-yl)pyridine-4-carboxamide
Show/Hide
|
C24H24N6O3
|
2
|
| 1 |
IC50 = 167 nM
|
|
|
| 2 |
Ki = 4.1 nM
|
|
|
|
CP0481851
|
US9242970, 254
Show/Hide
|
C21H22F3NO5
|
1
|
| 1 |
IC50 = 168 nM
|
|
|
|
CP0401034
|
(6R)-4-(benzenesulfonyl)-6-fluoro-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C20H22FN3O4S
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0413403
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-6-(5-methylpyridin-3-yl)-3-phenylpyridazine-4-carboxamide
Show/Hide
|
C25H23N5O3
|
2
|
| 1 |
IC50 = 170 nM
|
|
|
| 2 |
Ki = 11 nM
|
|
|
|
CP0450359
|
(R)-2-((R)-1-ethyl-4-(4-ethylphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
IC50 = 174 nM
|
|
|
|
CP0471479
|
(R)-2-((R)-1-ethyl-4-(4-isopropylphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
IC50 = 179 nM
|
|
|
|
CP0447530
|
3-ethyl-7-[(1R)-2-(methylamino)-2-oxo-1-phenylethyl]-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
Show/Hide
|
C27H30F3N5O2
|
1
|
| 1 |
IC50 = 194 nM
|
|
|
|
CP0473366
|
(2R)-2-[3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H29F3N4O
|
1
|
| 1 |
IC50 = 194 nM
|
|
|
|
CP0395536
|
N-[2-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C20H18FN7O
|
1
|
| 1 |
IC50 = 198 nM
|
|
|
|
CP0484191
|
[(7R)-4-(4-amino-5-methylfuro[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H24N8O2
|
2
|
| 1 |
IC50 = 210 nM
|
|
|
| 2 |
Ki = 25 nM
|
|
|
|
CP0433055
|
6-(2,6-dimethoxyphenyl)-1-(quinolin-3-ylmethyl)piperidin-2-one
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 = 217 nM
|
|
|
|
CP0381235
|
2-(1-ethyl-4-(4-methoxyphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C27H34N4O2
|
1
|
| 1 |
IC50 = 219 nM
|
|
|
|
CP0431186
|
(6S)-4-(benzenesulfonyl)-6-fluoro-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C20H22FN3O4S
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0542402
|
2-methyl-N-[[(2S,3R)-3-methyl-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
|
C28H29N3O3S
|
1
|
| 1 |
IC50 = 221 nM
|
|
|
|
CP0426830
|
(2R)-2-[3-ethyl-1-propyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C29H35F3N4O
|
1
|
| 1 |
IC50 = 225 nM
|
|
|
|
CP0375626
|
(2R)-2-[(8R)-1-chloro-3-ethyl-8-[2-[3-fluoro-4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27ClF4N4O
|
1
|
| 1 |
IC50 = 227 nM
|
|
|
|
CP0390766
|
4-(benzenesulfonyl)-8-quinoxalin-2-yl-1-oxa-4,8-diazaspiro[4.5]decane
Show/Hide
|
C21H22N4O3S
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0502544
|
N,N-diethyl-2-(4-methyl-N-(4-methylphenyl)sulfonylanilino)acetamide
Show/Hide
|
C20H26N2O3S
|
1
|
| 1 |
IC50 = 232 nM
|
|
|
|
CP0398947
|
2-(N-(5-(dimethylamino)-2-methoxyphenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C23H33N3O6S
|
1
|
| 1 |
IC50 = 239 nM
|
|
|
|
CP0367354
|
US9242970, 255
Show/Hide
|
C20H19F4NO4
|
1
|
| 1 |
IC50 = 242 nM
|
|
|
|
CP0874291
|
(rac)-(2-(3-methoxyphenethyl)piperidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
Show/Hide
|
C24H28N4O2
|
1
|
| 1 |
IC50 = 243 nM
|
|
|
|
CP0431890
|
[(7R)-4-[2-methoxy-5-(trifluoromethyl)pyrimidin-4-yl]-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C21H22F3N7O2
|
1
|
| 1 |
IC50 = 245 nM
|
|
|
|
CP0510325
|
N-ethyl-N-[(2R)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C23H24FN7O
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0523011
|
5-(2,6-dimethoxyphenyl)-3,3-dimethyl-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 252 nM
|
|
|
|
CP0464872
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-6-methyl-3-pyrimidin-2-ylpyridine-2-carboxamide
Show/Hide
|
C24H23FN6O2
|
1
|
| 1 |
IC50 = 254 nM
|
|
|
|
CP0481619
|
6-(2-methoxy-6-methylphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C21H22F3NO3
|
1
|
| 1 |
IC50 = 268 nM
|
|
|
|
CP0506237
|
(4-chlorophenyl)-[(3R,5S)-3,5-dimethyl-7-(trifluoromethyl)-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methanone
Show/Hide
|
C19H17ClF3NO2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0382728
|
[(7R)-4-(1,3-dimethylpyrazolo[3,4-d]pyrimidin-6-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H25N9O
|
2
|
| 1 |
IC50 = 280 nM
|
|
|
| 2 |
Ki = 92 nM
|
|
|
|
CP0420701
|
6-(2,6-dimethoxyphenyl)-4-methyl-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 297 nM
|
|
|
|
CP0421237
|
N-[(Z)-anthracen-9-ylmethylideneamino]-6-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-amine
Show/Hide
|
C25H18N6
|
3
|
| 1 |
IC50 = 300 nM
|
|
|
| 2 |
Ki = 400 nM
|
|
|
| 3 |
Ki = 11000 nM
|
|
|
|
CP0308272
|
(3S,5R)-1-(dibenzofuran-2-ylmethyl)-5-(2-fluoro-6-methoxyphenyl)-3-hydroxypyrrolidin-2-one
Show/Hide
|
C24H20FNO4
|
1
|
| 1 |
IC50 = 315 nM
|
|
|
|
CP0517461
|
N,N-diethyl-2-(N-(4-fluorophenyl)sulfonyl-4-methylanilino)acetamide
Show/Hide
|
C19H23FN2O3S
|
1
|
| 1 |
IC50 = 346 nM
|
|
|
|
CP0525371
|
6-(2,6-diethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C23H26F3NO4
|
1
|
| 1 |
IC50 = 395 nM
|
|
|
|
CP0481615
|
6-(2,6-dimethoxyphenyl)-4-methyl-1-[[4-(trifluoromethoxy)phenyl]methyl]piperazin-2-one
Show/Hide
|
C21H23F3N2O4
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0427133
|
1-benzyl-6-(2,6-dimethoxyphenyl)piperidin-2-one
Show/Hide
|
C20H23NO3
|
1
|
| 1 |
IC50 = 416 nM
|
|
|
|
CP0398145
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-6-(5-methylpyridin-3-yl)-3-phenyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxamide
Show/Hide
|
C27H23N5O4
|
2
|
| 1 |
IC50 = 420 nM
|
|
|
| 2 |
Ki = 9 nM
|
|
|
|
CP0850587
|
(rac)-(7-(3,4-dimethoxybenzyl)-4,5-dihydrothieno[2,3-c]pyridin-6(7H)-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
Show/Hide
|
C26H26N4O3S
|
1
|
| 1 |
IC50 = 428 nM
|
|
|
|
CP0492407
|
[(3R,5S)-7-bromo-3,5-dimethyl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]-(4-chlorophenyl)methanone
Show/Hide
|
C18H17BrClNO2
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0492689
|
2-(N-(2-chloro-5-(ethyl(methyl)amino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C23H32ClN3O5S
|
1
|
| 1 |
IC50 = 433 nM
|
|
|
|
CP0338429
|
[(2S,3R)-2-[(1,3-benzoxazol-2-ylamino)methyl]-3-methylpiperidin-1-yl]-(2-methyl-5-phenyl-1,3-thiazol-4-yl)methanone
Show/Hide
|
C25H26N4O2S
|
1
|
| 1 |
IC50 = 447 nM
|
|
|
|
CP0502220
|
2-(N-(2-chloro-5-cyanophenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C21H24ClN3O5S
|
1
|
| 1 |
IC50 = 463 nM
|
|
|
|
CP0475346
|
N-ethyl-5-fluoro-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)tetrazol-2-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C20H19F2N9O
|
1
|
| 1 |
IC50 = 471 nM
|
|
|
|
CP0421233
|
2-[2-(4-amino-1,2,5-oxadiazol-3-yl)benzimidazol-1-yl]-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
Show/Hide
|
C21H22N6O4
|
3
|
| 1 |
IC50 = 500 nM
|
|
|
| 2 |
Ki = 800 nM
|
|
|
| 3 |
Ki = 900 nM
|
|
|
|
CP0420704
|
6-(2,6-dimethoxyphenyl)-1-[(2-phenylphenyl)methyl]piperidin-2-one
Show/Hide
|
C26H27NO3
|
1
|
| 1 |
IC50 = 507 nM
|
|
|
|
CP0495605
|
N-ethyl-5-fluoro-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C23H21F2N7O
|
1
|
| 1 |
IC50 = 532 nM
|
|
|
|
CP0426709
|
N-[[(2S,4S)-4-fluoro-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C29H26FN3O2
|
1
|
| 1 |
IC50 = 541 nM
|
|
|
|
CP0192297
|
US9242970, 257
Show/Hide
|
C20H19ClF3NO4
|
1
|
| 1 |
IC50 = 563 nM
|
|
|
|
CP0420702
|
6-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperazin-2-one
Show/Hide
|
C20H21F3N2O4
|
1
|
| 1 |
IC50 = 589 nM
|
|
|
|
CP0420705
|
6-(2-methoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C20H20F3NO3
|
1
|
| 1 |
IC50 = 635 nM
|
|
|
|
CP0524998
|
N-[[(2S,3R)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]-3-methylpiperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H27FN4O2S
|
1
|
| 1 |
IC50 = 658 nM
|
|
|
|
CP0492691
|
N,N-diethyl-2-(N-(4-methoxyphenyl)sulfonyl-4-methylanilino)acetamide
Show/Hide
|
C20H26N2O4S
|
1
|
| 1 |
IC50 = 661 nM
|
|
|
|
CP0510326
|
US9242970, 253
Show/Hide
|
C20H20F3NO5
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0421235
|
ethyl 2-[2-[[5-[[(3,5-dimethoxybenzoyl)amino]methyl]-4-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]propanoylamino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
Show/Hide
|
C32H35N5O7S2
|
3
|
| 1 |
IC50 = 700 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
|
| 3 |
Ki = 1100 nM
|
|
|
|
CP0421236
|
3-(2-methoxyphenyl)-1'-prop-2-enylspiro[1H-quinazoline-2,3'-indole]-2',4-dione
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C25H21N3O3
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3
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| 1 |
IC50 = 700 nM
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| 2 |
Ki = 1000 nM
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| 3 |
Ki = 1200 nM
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CP0499682
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4-(benzenesulfonyl)-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
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C20H23N3O4S
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1
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| 1 |
IC50 = 710 nM
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CP0492406
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[(3R,5S)-7-chloro-3,5-dimethyl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]-(4-chlorophenyl)methanone
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C18H17Cl2NO2
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1
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| 1 |
IC50 = 730 nM
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CP0444256
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4-(2,6-dimethoxyphenyl)-3-[[4-(trifluoromethoxy)phenyl]methyl]-1,3-oxazolidin-2-one
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C19H18F3NO5
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1
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| 1 |
IC50 = 771 nM
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CP0502543
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2-(N-(4-chloro-3-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
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C22H30ClN3O5S
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1
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| 1 |
IC50 = 789 nM
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CP0474342
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2-(2-chloro-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
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C19H23ClN2O3S
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1
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| 1 |
IC50 = 800 nM
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CP0421240
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N'-(2,5-dichlorophenyl)-2-hydroxy-2,2-bis(4-methylphenyl)acetohydrazide
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C22H20Cl2N2O2
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3
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| 1 |
IC50 = 800 nM
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| 2 |
Ki = 1300 nM
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| 3 |
Ki = 1700 nM
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CP0412312
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N,N-diethyl-2-(N-(3-fluorophenyl)sulfonyl-4-methylanilino)acetamide
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C19H23FN2O3S
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1
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| 1 |
IC50 = 839 nM
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CP0455307
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N-[(2S)-1-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
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C21H20FN7O
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1
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| 1 |
IC50 = 840 nM
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CP0455306
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N-ethyl-5-fluoro-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
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C21H19F2N7O2
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1
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| 1 |
IC50 = 887 nM
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CP0481620
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6-(2,6-dimethoxyphenyl)-3-methyl-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
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C22H24F3NO4
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1
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| 1 |
IC50 = 894 nM
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CP0384610
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(2R)-1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
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C24H26N2O4
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2
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| 1 |
IC50 = 900 nM
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| 2 |
Ki = 1400 nM
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CP0568353
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N-[(2S)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]-3-methylbutan-2-yl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
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C24H26FN7O
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1
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| 1 |
IC50 = 952 nM
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CP0472559
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[(2R,5R)-5-[4-[(dimethylamino)methyl]-5-phenyl-1,3-oxazol-2-yl]-2-methylpiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
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C27H30N6O2
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1
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| 1 |
IC50 = 983 nM
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CP0399392
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4-(benzenesulfonyl)-6,6-difluoro-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
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C20H21F2N3O4S
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1
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| 1 |
IC50 = 1000 nM
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CP0444287
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6-(2,6-dimethoxyphenyl)-1-(quinolin-6-ylmethyl)piperidin-2-one
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C23H24N2O3
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1
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| 1 |
IC50 = 1002 nM
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CP0433581
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-4-(3-fluorophenyl)-2-(5-methylpyridin-3-yl)-1,3-thiazole-5-carboxamide
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C24H21FN4O3S
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2
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| 1 |
IC50 = 1060 nM
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| 2 |
Ki = 140 nM
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CP0444259
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4-(2,6-dimethoxyphenyl)-3-[[4-(trifluoromethoxy)phenyl]methyl]-3-azabicyclo[3.1.0]hexan-2-one
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C21H20F3NO4
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1
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| 1 |
IC50 = 1070 nM
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CP0481613
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6-(2,6-dimethoxyphenyl)-4,4-dimethyl-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
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C23H26F3NO4
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1
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| 1 |
IC50 = 1080 nM
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CP0398948
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2-(N-(2-chloro-5-(1H-pyrrol-1-yl)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
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C24H28ClN3O5S
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1
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| 1 |
IC50 = 1161 nM
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CP0422493
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2-(4-cyano-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
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C20H23N3O3S
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1
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| 1 |
IC50 = 1187 nM
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CP0433077
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6-(2,6-dimethoxyphenyl)-3,3-dimethyl-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
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C23H26F3NO4
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1
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| 1 |
IC50 = 1291 nM
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CP0534500
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N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-6-methyl-3-pyrimidin-2-ylpyridine-2-carboxamide
Show/Hide
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C23H23FN8O
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1
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| 1 |
IC50 = 1310 nM
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CP0481618
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6-(2,6-dimethoxyphenyl)-1-(2-phenylethyl)piperidin-2-one
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C21H25NO3
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1
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| 1 |
IC50 = 1331 nM
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CP0378611
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-pyridazin-4-ylpyridine-4-carboxamide
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C24H22N6O3
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2
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| 1 |
IC50 = 1450 nM
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| 2 |
Ki = 193 nM
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CP0511742
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N-[2-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-5-methyl-2-(triazol-2-yl)benzamide
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C20H18FN7O
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1
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| 1 |
IC50 = 1460 nM
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CP0517187
|
US9828368, Example 57
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C26H25N5O4
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1
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| 1 |
IC50 = 1589 nM
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CP0492699
|
2-(N-(2-chloro-5-(pyrrolidin-1-yl)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
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C24H32ClN3O5S
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1
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| 1 |
IC50 = 1606 nM
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CP0421238
|
methyl 2-[acetyl-[[5-bromo-2-[(2-chlorobenzoyl)amino]phenyl]-phenylmethyl]amino]acetate
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C25H22BrClN2O4
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2
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| 1 |
IC50 = 1700 nM
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| 2 |
Ki = 2500 nM
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CP0497676
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N,N-diethyl-2-(4-methyl-N-[4-(trifluoromethoxy)phenyl]sulfonylanilino)acetamide
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C20H23F3N2O4S
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1
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| 1 |
IC50 = 1822 nM
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CP0522520
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N-[[(2S)-5-amino-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
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C27H27N5O2S
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1
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| 1 |
IC50 = 2000 nM
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CP0260679
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(3R,5S)-3-amino-5-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
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C20H21F3N2O4
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1
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| 1 |
IC50 = 2050 nM
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CP0503014
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2-(N-(2-chloro-5-(diethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
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C24H34ClN3O5S
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1
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| 1 |
IC50 = 2405 nM
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CP0543556
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[(7R)-4-(2-chloro-5-methylpyrimidin-4-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
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C20H22ClN7O
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2
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| 1 |
IC50 = 2600 nM
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| 2 |
Ki = 760 nM
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CP0474075
|
(2R)-2-[1-ethoxy-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
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C28H33F3N4O2
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1
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| 1 |
IC50 = 2746 nM
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CP0474054
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(2R)-2-[3-ethyl-1-propan-2-yl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
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C29H35F3N4O
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1
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| 1 |
IC50 = 2904 nM
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CP0459007
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(4-chlorophenyl)-[(3R,5S)-7-fluoro-3,5-dimethyl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methanone
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C18H17ClFNO2
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1
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| 1 |
IC50 = 3000 nM
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CP0428727
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[(7R)-4-(2,5-dichloropyrimidin-4-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
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C19H19Cl2N7O
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2
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| 1 |
IC50 = 3200 nM
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| 2 |
Ki = 850 nM
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CP0492692
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N,N-diethyl-2-(N-(2-fluorophenyl)sulfonyl-4-methylanilino)acetamide
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C19H23FN2O3S
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1
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| 1 |
IC50 = 3372 nM
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CP0473839
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-morpholin-4-ylpyridine-4-carboxamide
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C24H27N5O4
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2
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| 1 |
IC50 = 3502 nM
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| 2 |
Ki = 75 nM
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CP0283391
|
US9242970, 263
Show/Hide
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C22H24F3NO4
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1
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| 1 |
IC50 = 3610 nM
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CP0115910
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[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C23H19F2N5O2
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2
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| 1 |
IC50 = 4184 nM
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| 2 |
Ki = 521 nM
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CP0523451
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(4-chlorophenyl)-[(3R,5S)-3,5-dimethyl-7-methylsulfonyl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methanone
Show/Hide
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C19H20ClNO4S
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1
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| 1 |
IC50 = 4700 nM
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CP0499780
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(3R,5S)-5-(2,6-dimethoxyphenyl)-3-(methylamino)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
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C21H23F3N2O4
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1
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| 1 |
IC50 = 5810 nM
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CP0495913
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(4-chlorophenyl)-[(3R,5S)-3,5-dimethyl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methanone
Show/Hide
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C18H18ClNO2
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1
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| 1 |
IC50 = 6400 nM
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CP0349345
|
US9242970, 262
Show/Hide
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C21H22F3NO5
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1
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| 1 |
IC50 = 6940 nM
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CP0392389
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(3R,5S)-4-(4-chlorobenzoyl)-3,5-dimethyl-3,5-dihydro-2H-1,4-benzoxazepine-7-carbonitrile
Show/Hide
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C19H17ClN2O2
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1
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| 1 |
IC50 = 8200 nM
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CP0367355
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(3S,5S)-5-(2,6-dimethoxyphenyl)-3-(dimethylamino)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
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C22H25F3N2O4
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1
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| 1 |
IC50 = 8300 nM
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CP0308200
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(3S,5S)-3-amino-5-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
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C20H21F3N2O4
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1
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| 1 |
IC50 = 9490 nM
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CP0044586
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3-methoxy-2-methyl-N-[[(2S,3R)-3-methyl-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]benzamide
Show/Hide
|
C27H31N3O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0420710
|
6-(2,6-dimethoxyphenyl)-1-phenylpiperidin-2-one
Show/Hide
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C19H21NO3
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1
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| 1 |
IC50 > 10000 nM
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CP0427134
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1-[[4-(trifluoromethoxy)phenyl]methyl]-2-(2,4,6-trimethoxyphenyl)piperidine
Show/Hide
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C22H26F3NO4
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1
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| 1 |
IC50 > 10000 nM
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CP0523010
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3-(2,6-dimethoxyphenyl)-2-[[4-(trifluoromethoxy)phenyl]methyl]-3H-isoindol-1-one
Show/Hide
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C24H20F3NO4
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1
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| 1 |
IC50 > 10000 nM
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CP0248144
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(3S,5S)-5-(2,6-dimethoxyphenyl)-3-(methylamino)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
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C21H23F3N2O4
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1
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| 1 |
IC50 > 10000 nM
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CP0349346
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(3R,5S)-5-(2,6-dimethoxyphenyl)-3-(dimethylamino)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C22H25F3N2O4
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1
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| 1 |
IC50 > 10000 nM
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CP0481852
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(3S,5S)-5-(2,6-dimethoxyphenyl)-3-ethoxy-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
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C22H24F3NO5
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1
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| 1 |
IC50 > 10000 nM
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CP0380078
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[(7R)-4-(2,5-dimethylpyrimidin-4-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C21H25N7O
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki = 3600 nM
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CP0384924
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[(7R)-4-[2-chloro-5-(trifluoromethyl)pyrimidin-4-yl]-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C20H19ClF3N7O
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki = 1100 nM
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CP0384925
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[(7R)-4-(5-chloro-2-methylpyrimidin-4-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C20H22ClN7O
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki = 1800 nM
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CP0428726
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[(7R)-7-methyl-4-[2-methyl-5-(trifluoromethyl)pyrimidin-4-yl]-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C21H22F3N7O
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki = 4200 nM
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CP0085046
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[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-imidazo[1,5-a]pyridin-8-ylmethanone
Show/Hide
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C22H18F2N4O2
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki = 1009 nM
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CP0085047
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[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-(1H-imidazo[4,5-c]pyridin-4-yl)methanone
Show/Hide
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C21H17F2N5O2
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki = 2143 nM
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CP0421232
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6-(3,5-dimethylpyrazol-1-yl)-4-N-phenyl-2-N-[(Z)-[(E)-4-phenylbut-3-en-2-ylidene]amino]-1,3,5-triazine-2,4-diamine
Show/Hide
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C24H24N8
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2
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| 1 |
IC50 = 11800 nM
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| 2 |
Ki = 17800 nM
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CP0422093
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(2S)-1-[2-(1,5-dimethylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H27N5O2S
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1
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| 1 |
Ki = 0.09 nM
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CP0515983
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(2S)-1-[2-(1,6-dimethylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
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C26H27N5O2S
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1
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| 1 |
Ki = 0.1 nM
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CP0059177
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(2S)-1-[2-(1-methylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C27H26N4O2S
|
1
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| 1 |
Ki = 0.2 nM
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CP0391199
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(2S)-1-[2-[(6-methyl-1H-benzimidazol-2-yl)sulfanyl]acetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C25H25N5O2S
|
1
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| 1 |
Ki = 0.2 nM
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CP0505828
|
4-fluoro-N-[[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]benzamide
Show/Hide
|
C26H25FN2O2
|
1
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| 1 |
Ki = 0.2512 nM
|
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CP0436316
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(2S)-1-[2-(1-methylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
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C25H25N5O2S
|
1
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| 1 |
Ki = 0.3 nM
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CP0527425
|
US9029364, 1
Show/Hide
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C21H22FN5O2S
|
1
|
| 1 |
Ki = 0.38 nM
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CP0087270
|
SB-649868
Show/Hide
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C26H24FN3O3S
|
3
|
| 1 |
Ki = 0.3981 nM
|
|
|
| 2 |
Ki = 1.288 nM
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| 3 |
Ki = 8.5 nM
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CP0128556
|
5-(5-chloropyridin-3-yl)-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-pyridin-2-ylpyridine-3-carboxamide
Show/Hide
|
C24H20ClN5O3
|
1
|
| 1 |
Ki = 0.5 nM
|
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CP0382196
|
(2S)-1-[2-(1H-benzimidazol-2-ylsulfanyl)acetyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H24N4O2S
|
1
|
| 1 |
Ki = 0.6 nM
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CP0521843
|
[(2S)-2-[2-(2,4-difluorophenoxy)ethyl]piperidin-1-yl]-(2-phenylphenyl)methanone
Show/Hide
|
C26H25F2NO2
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0394570
|
(2S)-1-[3-(1-methylbenzimidazol-2-yl)propanoyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C28H28N4O2
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0385077
|
US9029364, 3
Show/Hide
|
C20H20FN5O2S
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0433114
|
(S)-1-(2-(1H-benzo[d]imidazol-2-ylthio)acetyl)-N-(2-(1H-pyrrol-1-yl)phenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C24H23N5O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0404095
|
(1R,2S)-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl)-2-[[4-(methoxymethyl)-2-methylpyrimidin-5-yl]oxymethyl]cyclopropane-1-carboxamide
Show/Hide
|
C23H22F2N4O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0411322
|
(1R,2S)-N-(5-fluoropyridin-2-yl)-2-[[4-(methoxymethyl)-2-methylpyrimidin-5-yl]oxymethyl]-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C23H23FN4O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0262389
|
N-(3,5-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H22N4O3S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0462719
|
US9029364, 5
Show/Hide
|
C20H20ClN5O2S
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0394568
|
(2S)-1-[3-(1H-benzimidazol-2-yl)propanoyl]-N-[2-(2-methoxyphenyl)phenyl]pyrrolidine-2-carboxamide
Show/Hide
|
C28H28N4O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0405058
|
(2S)-1-[3-(1-methylbenzimidazol-2-yl)propanoyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H27N5O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0433116
|
(2S)-1-[2-(1,3-benzothiazol-2-ylsulfanyl)acetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C24H22N4O2S2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0404057
|
(1R,2S)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-N-(5-fluoro-6-methoxypyridin-2-yl)-2-(3-fluorophenyl)cyclopropane-1-carboxamide
Show/Hide
|
C23H22F2N4O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0467638
|
(1R,2S)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-N-(5-fluoro-4-methoxypyridin-2-yl)-2-(3-fluorophenyl)cyclopropane-1-carboxamide
Show/Hide
|
C23H22F2N4O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0415631
|
US9029364, 8
Show/Hide
|
C20H20ClN5O2S
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0508125
|
N-(3,4-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H22N4O3S
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0508324
|
(4,4-difluoro-3-isoquinolin-1-yloxypiperidin-1-yl)-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H19F2N5O2
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0382194
|
(2S)-1-[2-(1H-benzimidazol-2-ylsulfanyl)acetyl]-N-(2-phenoxyphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H24N4O3S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0382195
|
(2S)-1-[3-(1H-benzimidazol-2-yl)propanoyl]-N-[2-(2-fluorophenyl)phenyl]pyrrolidine-2-carboxamide
Show/Hide
|
C27H25FN4O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0471684
|
US8623863, 2-8
Show/Hide
|
C25H29FN4O2
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0544447
|
US8623863, 3-5
Show/Hide
|
C24H26FN3O2S
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0519859
|
US8623863, 3-2
Show/Hide
|
C26H29FN2O2S
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0395789
|
(1R,2S)-N-(5-cyanopyridin-2-yl)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-2-(3-fluorophenyl)cyclopropane-1-carboxamide
Show/Hide
|
C23H20FN5O2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0390193
|
1-phenyl-3-[[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]urea
Show/Hide
|
C26H27N3O2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0382190
|
(2S)-1-[3-(1H-benzimidazol-2-yl)propanoyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C27H26N4O2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0513079
|
(1R,2S)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-2-(3-fluoro-4-methoxyphenyl)-N-(5-fluoropyridin-2-yl)cyclopropane-1-carboxamide
Show/Hide
|
C23H22F2N4O3
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0411781
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-N,2-diphenylcyclopropane-1-carboxamide
Show/Hide
|
C25H25NO4
|
1
|
| 1 |
Ki = 7.2 nM
|
|
|
|
CP0481486
|
US9029364, 13
Show/Hide
|
C20H21ClN6O2S
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0468161
|
US8623863, 1-8
Show/Hide
|
C24H27FN4O2
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0382191
|
(2S)-1-[2-(1,3-benzoxazol-2-ylsulfanyl)acetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C24H22N4O3S
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0504443
|
2-{(5S)-5-Methyl-4-[2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}quinazoline
Show/Hide
|
C23H23N7O
|
1
|
| 1 |
Ki = 8.5 nM
|
|
|
|
CP0385441
|
US8623863, 3-8
Show/Hide
|
C24H27FN4O3
|
1
|
| 1 |
Ki = 8.7 nM
|
|
|
|
CP0573639
|
[(2R,5R)-2-methyl-5-quinolin-2-yloxypiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0545696
|
US9029364, 4
Show/Hide
|
C21H23N5O2S
|
1
|
| 1 |
Ki = 9.7 nM
|
|
|
|
CP0438206
|
US8623863, 2-10
Show/Hide
|
C23H26FN5O2
|
1
|
| 1 |
Ki = 9.7 nM
|
|
|
|
CP0403002
|
US8623863, 3-3
Show/Hide
|
C27H30FN3O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0441542
|
US8623863, 2-9
Show/Hide
|
C24H27FN4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0382193
|
(2S)-1-[3-(1H-benzimidazol-2-yl)propanoyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C25H25N5O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0433115
|
(2S)-1-[2-(1H-benzimidazol-2-ylsulfanyl)acetyl]-N-(4-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H24N4O2S
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0463175
|
US8623863, 4-9
Show/Hide
|
C23H25FN4O3
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0573638
|
[(2R)-5-[(5-fluoropyridin-2-yl)oxymethyl]-2-methylpiperidin-1-yl]-(5-methyl-2-pyrimidin-2-ylphenyl)methanone
Show/Hide
|
C24H25FN4O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0472606
|
US8623863, 3-4
Show/Hide
|
C24H26FN3O3
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0199037
|
(1R,2S)-N-(5-cyanopyridin-2-yl)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C25H23N3O4
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0400057
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-N-(4-methyl-1,3-thiazol-2-yl)-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C23H24N2O4S
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0474805
|
US8623863, 3-6
Show/Hide
|
C25H27FN4O2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0566876
|
[4,4-difluoro-3-[4-(trifluoromethyl)pyridin-2-yl]oxypiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C20H16F5N5O2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0407070
|
US9029364, 2
Show/Hide
|
C20H21N5O2S
|
1
|
| 1 |
Ki = 15.3 nM
|
|
|
|
CP0389412
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxy-5-methylphenyl)acetamide
Show/Hide
|
C22H22N4O4S
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0510631
|
5-(5-chloropyridin-3-yl)-N-(5,6-dimethoxypyridin-2-yl)-2-pyridin-2-ylpyridine-3-carboxamide
Show/Hide
|
C23H18ClN5O3
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0458767
|
N-[[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]benzamide
Show/Hide
|
C26H26N2O2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0474851
|
1-phenyl-3-[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]propan-1-one
Show/Hide
|
C27H27NO2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0482122
|
[2-[2-(4-fluorophenoxy)ethyl]piperidin-1-yl]-(2-phenylphenyl)methanone
Show/Hide
|
C26H26FNO2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0296027
|
[4-(6-chloro-1,3-benzothiazol-2-yl)-1,4-diazepan-1-yl]-(2,6-dimethoxyphenyl)methanone
Show/Hide
|
C21H22ClN3O3S
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0414117
|
[(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropyl]-(6-fluoro-1H-benzimidazol-2-yl)methanone
Show/Hide
|
C26H23FN2O4
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0566634
|
[(3R)-3-quinolin-2-yloxypiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H21N5O2
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0413168
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-N-(5-methyl-1,2-oxazol-3-yl)-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C23H24N2O5
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0542117
|
US8623863, 2-11
Show/Hide
|
C22H24FN5O2
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0489661
|
N-(4-acetylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H20N4O4S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0474850
|
4-fluoro-N-[[(2R)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]benzamide
Show/Hide
|
C26H25FN2O2
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0499127
|
N-phenyl-2-[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]acetamide
Show/Hide
|
C26H26N2O2
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0544771
|
US9029364, 12
Show/Hide
|
C20H21ClN6O2S
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0414115
|
(1R,2S)-N-(4-cyanopyridin-2-yl)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C25H23N3O4
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0418621
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-N-(5-methyl-1,3-thiazol-2-yl)-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C23H24N2O4S
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0400055
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0522128
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methylphenyl)acetamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0527228
|
N-(3-chloro-4-fluorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C20H16ClFN4O3S
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0399525
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-6-(5-methylpyridin-3-yl)-3-phenylpyridine-2-carboxamide
Show/Hide
|
C26H24N4O3
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0542116
|
US9029364, 6
Show/Hide
|
C21H20N6O2S
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0489666
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(3-methylphenyl)acetamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0544205
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenyl-N-pyridin-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0386670
|
N-(3-chlorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C20H17ClN4O3S
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0543529
|
US9029364, 7
Show/Hide
|
C21H20F3N5O2S
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0387710
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenyl-N-pyridin-4-ylcyclopropane-1-carboxamide
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0458985
|
US9029364, 17
Show/Hide
|
C20H21N5OS2
|
1
|
| 1 |
Ki = 98 nM
|
|
|
|
CP0305849
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)acetamide
Show/Hide
|
C18H17N5O3S2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0493788
|
N-(4-chlorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C20H17ClN4O3S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0566636
|
[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-(1H-pyrrolo[2,3-c]pyridin-4-yl)methanone
Show/Hide
|
C22H18F2N4O2
|
1
|
| 1 |
Ki = 108 nM
|
|
|
|
CP0566635
|
[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-(1H-indol-4-yl)methanone
Show/Hide
|
C23H19F2N3O2
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0520782
|
[(2S)-2-[2-(4-fluorophenoxy)ethyl]piperidin-1-yl]-naphthalen-1-ylmethanone
Show/Hide
|
C24H24FNO2
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0379310
|
(1R,2S)-2-(3,4-dimethoxyphenyl)-2-(phenoxymethyl)-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
Ki = 129 nM
|
|
|
|
CP0382197
|
(R)-1-(2-(1H-benzo[d]imidazol-2-ylthio)acetyl)-N-(2-(1H-pyrrol-1-yl)phenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C24H23N5O2S
|
1
|
| 1 |
Ki = 131 nM
|
|
|
|
CP0459015
|
US9029364, 9
Show/Hide
|
C21H20N6O2S
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0385165
|
US9029364, 14
Show/Hide
|
C20H21ClN6O3S
|
1
|
| 1 |
Ki = 155 nM
|
|
|
|
CP0489665
|
N-[4-(dimethylamino)phenyl]-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H23N5O3S
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0520084
|
N-(4-fluorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C20H17FN4O3S
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0422531
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US9029364, 15
Show/Hide
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C20H20FN5O3S
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1
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| 1 |
Ki = 170 nM
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CP0474548
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US9029364, 10
Show/Hide
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C21H23N5O2S
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1
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| 1 |
Ki = 192 nM
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CP0395671
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[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-[3-(1H-imidazol-2-yl)phenyl]methanone
Show/Hide
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C24H20F2N4O2
|
1
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| 1 |
Ki = 193 nM
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CP0417765
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2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methoxyphenyl)acetamide
Show/Hide
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C21H20N4O4S
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1
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| 1 |
Ki = 199.53 nM
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CP0431885
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[3-(1,3-benzothiazol-2-yloxy)-4,4-difluoropiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C21H17F2N5O2S
|
1
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| 1 |
Ki = 220 nM
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CP0389406
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N-[3-(1,3-benzodioxol-5-yl)phenyl]-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
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C27H22N4O5S
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1
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| 1 |
Ki = 251.19 nM
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CP0198122
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[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-(2-pyrazol-1-ylphenyl)methanone
Show/Hide
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C24H20F2N4O2
|
1
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| 1 |
Ki = 271 nM
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CP0085207
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(4,4-difluoro-3-quinolin-4-yloxypiperidin-1-yl)-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C23H19F2N5O2
|
1
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| 1 |
Ki = 277 nM
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CP0501979
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(2S)-1-[2-(1H-benzimidazol-2-ylsulfanyl)acetyl]-N-(3-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
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C26H24N4O2S
|
1
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| 1 |
Ki = 280 nM
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CP0400935
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[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-(2-pyrimidin-2-ylphenyl)methanone
Show/Hide
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C25H20F2N4O2
|
1
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| 1 |
Ki = 281 nM
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CP0489664
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N-(3-acetylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
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C22H20N4O4S
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1
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| 1 |
Ki = 316.23 nM
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CP0140089
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(4,4-difluoro-3-isoquinolin-3-yloxypiperidin-1-yl)-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C23H19F2N5O2
|
1
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| 1 |
Ki = 379 nM
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CP0400056
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(1R,2S)-2-[[4-methoxy-3-(methoxymethyl)phenoxy]methyl]-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
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C25H26N2O4
|
1
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| 1 |
Ki = 384 nM
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CP0403958
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2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
Show/Hide
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C17H16N6O3S2
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1
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| 1 |
Ki = 398.11 nM
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CP0508126
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N-(2,5-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
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C22H22N4O3S
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1
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| 1 |
Ki = 398.11 nM
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CP0522131
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N-(3,5-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-pyridin-2-ylacetamide
Show/Hide
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C27H25N5O3S
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1
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| 1 |
Ki = 398.11 nM
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CP0544419
|
US9029364, 16
Show/Hide
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C20H20FN5O4S
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1
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| 1 |
Ki = 400 nM
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CP0087272
|
(2R)-2-[(1S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-2-phenyl-N-propan-2-ylacetamide
Show/Hide
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C31H38N2O5
|
1
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| 1 |
Ki = 417 nM
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CP0085208
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[3-(1,3-benzoxazol-2-yloxy)-4,4-difluoropiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C21H17F2N5O3
|
1
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| 1 |
Ki = 467 nM
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CP0237171
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[4,4-difluoro-3-[5-(trifluoromethyl)pyridin-2-yl]oxypiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C20H16F5N5O2
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1
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| 1 |
Ki = 467 nM
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CP0389413
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N-(3-fluorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
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C20H17FN4O3S
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1
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| 1 |
Ki = 501.19 nM
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CP0493790
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2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxyphenyl)acetamide
Show/Hide
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C21H20N4O4S
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1
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| 1 |
Ki = 501.19 nM
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CP0523671
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N-(2,4-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
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C22H22N4O3S
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1
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| 1 |
Ki = 501.19 nM
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CP0482124
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[2-[2-(3,4-dichlorophenoxy)ethyl]piperidin-1-yl]-(3-methoxyphenyl)methanone
Show/Hide
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C21H23Cl2NO3
|
1
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| 1 |
Ki = 501.19 nM
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CP0316828
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[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-(1H-pyrrolo[3,2-c]pyridin-4-yl)methanone
Show/Hide
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C22H18F2N4O2
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1
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| 1 |
Ki = 521 nM
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CP0462533
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(2S)-1-[2-(1H-benzimidazol-2-ylsulfanyl)acetyl]-N-phenylpyrrolidine-2-carboxamide
Show/Hide
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C20H20N4O2S
|
1
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| 1 |
Ki = 560 nM
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CP0398519
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(1R,2S)-2-[(4-methoxyphenoxy)methyl]-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
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C23H22N2O3
|
1
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| 1 |
Ki = 588 nM
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CP0493584
|
[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-(3-pyrazol-1-ylphenyl)methanone
Show/Hide
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C24H20F2N4O2
|
1
|
| 1 |
Ki = 627 nM
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CP0489663
|
N-(3,5-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-piperazin-2-ylacetamide
Show/Hide
|
C26H30N6O3S
|
1
|
| 1 |
Ki = 630.96 nM
|
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CP0456216
|
3-[2-[2-(3,4-dichlorophenoxy)ethyl]piperidine-1-carbonyl]benzonitrile
Show/Hide
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C21H20Cl2N2O2
|
1
|
| 1 |
Ki = 630.96 nM
|
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CP0044395
|
1-(2-methyl-1,3-benzoxazol-6-yl)-3-(1,5-naphthyridin-4-yl)urea
Show/Hide
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C17H13N5O2
|
1
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| 1 |
Ki = 835 nM
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CP0573909
|
(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-quinolin-5-ylmethanone
Show/Hide
|
C24H19F2N3O2
|
1
|
| 1 |
Ki = 861 nM
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CP0565925
|
[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-[3-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H19F2N5O2
|
1
|
| 1 |
Ki = 871 nM
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CP0231946
|
[4,4-difluoro-3-[6-(trifluoromethyl)pyridin-2-yl]oxypiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C20H16F5N5O2
|
1
|
| 1 |
Ki = 907 nM
|
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CP0198123
|
(4,4-difluoro-3-quinoxalin-2-yloxypiperidin-1-yl)-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H18F2N6O2
|
1
|
| 1 |
Ki = 933 nM
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CP0398234
|
(1R,2S)-2-(phenoxymethyl)-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
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C22H20N2O2
|
1
|
| 1 |
Ki = 967 nM
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CP0403957
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(1,3-thiazol-2-yl)acetamide
Show/Hide
|
C17H15N5O3S2
|
1
|
| 1 |
Ki = 1000 nM
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CP0489667
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-phenylacetamide
Show/Hide
|
C20H18N4O3S
|
1
|
| 1 |
Ki = 1000 nM
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CP0493789
|
N-(2,3-dihydroindol-1-yl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H21N5O3S
|
1
|
| 1 |
Ki = 1000 nM
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CP0198745
|
(4,4-difluoro-3-pyridin-2-yloxypiperidin-1-yl)-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C19H17F2N5O2
|
1
|
| 1 |
Ki = 1038 nM
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CP0419323
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(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H19F2N5O2
|
1
|
| 1 |
Ki = 1137 nM
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CP0214632
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(2,6-difluoro-3-methoxyphenyl)-[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]methanone
Show/Hide
|
C22H18F4N2O3
|
1
|
| 1 |
Ki = 1227 nM
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CP0512555
|
4-fluoro-N-methyl-N-[[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]benzamide
Show/Hide
|
C27H27FN2O2
|
1
|
| 1 |
Ki = 1258.93 nM
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CP0400058
|
(1R,2S)-2-[(3-methoxyphenoxy)methyl]-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C23H22N2O3
|
1
|
| 1 |
Ki = 1330 nM
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CP0446055
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1H-benzimidazol-4-yl-[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]methanone
Show/Hide
|
C22H18F2N4O2
|
1
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| 1 |
Ki = 1409 nM
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CP0145920
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(4,4-difluoro-3-quinazolin-2-yloxypiperidin-1-yl)-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H18F2N6O2
|
1
|
| 1 |
Ki = 1470 nM
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CP0240305
|
[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-(1H-pyrrolo[2,3-b]pyridin-4-yl)methanone
Show/Hide
|
C22H18F2N4O2
|
1
|
| 1 |
Ki = 1564 nM
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CP0376074
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-phenylethyl)acetamide
Show/Hide
|
C22H22N4O3S
|
1
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| 1 |
Ki = 1584.89 nM
|
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CP0270268
|
(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-(2-fluoro-5-methoxyphenyl)methanone
Show/Hide
|
C22H19F3N2O3
|
1
|
| 1 |
Ki = 1617 nM
|
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CP0489662
|
N-(3,5-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-pyridin-3-ylacetamide
Show/Hide
|
C27H25N5O3S
|
1
|
| 1 |
Ki = 1995.26 nM
|
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CP0493791
|
N-(2-fluorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C20H17FN4O3S
|
1
|
| 1 |
Ki = 1995.26 nM
|
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CP0387709
|
(1R,2S)-2-[[3-methoxy-4-(methoxymethyl)phenoxy]methyl]-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C25H26N2O4
|
1
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| 1 |
Ki = 3336 nM
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CP0414240
|
N-[[(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropyl]methyl]aniline
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki = 4226 nM
|
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CP0395672
|
[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-[3-(triazol-1-yl)phenyl]methanone
Show/Hide
|
C23H19F2N5O2
|
1
|
| 1 |
Ki = 4306 nM
|
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CP0387588
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-N-methyl-N,2-diphenylcyclopropane-1-carboxamide
Show/Hide
|
C26H27NO4
|
1
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| 1 |
Ki = 4679 nM
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CP0386590
|
(1R,2S)-N-cyclohexyl-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C25H31NO4
|
1
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| 1 |
Ki = 7846 nM
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CP0494472
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[(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropyl]-phenylmethanone
Show/Hide
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C25H24O4
|
1
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| 1 |
Ki = 8654 nM
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CP0387616
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1-[(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropyl]-2-phenylethanone
Show/Hide
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C26H26O4
|
1
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| 1 |
Ki > 10000 nM
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CP0400054
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3,4-dihydro-2H-quinolin-1-yl-[(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropyl]methanone
Show/Hide
|
C28H29NO4
|
1
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| 1 |
Ki > 10000 nM
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CP0153468
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(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-phenylmethanone
Show/Hide
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C21H18F2N2O2
|
1
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| 1 |
Ki > 12660 nM
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CP0518097
|
(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-imidazo[1,5-a]pyridin-8-ylmethanone
Show/Hide
|
C22H18F2N4O2
|
1
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| 1 |
Ki > 12720 nM
|
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CP0389407
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C14H14N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
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CP0505375
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N-(2,3-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H22N4O3S
|
1
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| 1 |
Ki > 15848.93 nM
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CP0520085
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2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methylphenyl)acetamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
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CP0522129
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N-(2,6-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H22N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
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CP0522130
|
N-butan-2-yl-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C18H22N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
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CP0214631
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[4,4-difluoro-3-(1,8-naphthyridin-2-yloxy)piperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H18F2N6O2
|
1
|
| 1 |
Ki > 1407 nM
|
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|
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CP0085210
|
(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-(2-fluorophenyl)methanone
Show/Hide
|
C21H17F3N2O2
|
1
|
| 1 |
Ki > 1770 nM
|
|
|
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CP0566637
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[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-(1H-indazol-4-yl)methanone
Show/Hide
|
C22H18F2N4O2
|
1
|
| 1 |
Ki > 1935 nM
|
|
|
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CP0446056
|
(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-imidazo[1,5-a]pyridin-5-ylmethanone
Show/Hide
|
C22H18F2N4O2
|
1
|
| 1 |
Ki > 2096 nM
|
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CP0303317
|
(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-(2-methoxyphenyl)methanone
Show/Hide
|
C22H20F2N2O3
|
1
|
| 1 |
Ki > 2633 nM
|
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CP0532990
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(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-(2-methylphenyl)methanone
Show/Hide
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C22H20F2N2O2
|
1
|
| 1 |
Ki > 2633 nM
|
|
|
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CP0390190
|
[2-[2-(3,4-dichlorophenoxy)ethyl]piperidin-1-yl]-(3,4-dichlorophenyl)methanone
Show/Hide
|
C20H19Cl4NO2
|
1
|
| 1 |
Ki > 3162.28 nM
|
|
|
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CP0400937
|
(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-imidazo[1,2-a]pyridin-5-ylmethanone
Show/Hide
|
C22H18F2N4O2
|
1
|
| 1 |
Ki > 3327 nM
|
|
|
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CP0573641
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(4,4-difluoro-3-hydroxypiperidin-1-yl)-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C14H14F2N4O2
|
1
|
| 1 |
Ki > 3370 nM
|
|
|
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CP0140091
|
(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-(3-fluorophenyl)methanone
Show/Hide
|
C21H17F3N2O2
|
1
|
| 1 |
Ki > 4379 nM
|
|
|
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CP0145922
|
(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-(3-methoxyphenyl)methanone
Show/Hide
|
C22H20F2N2O3
|
1
|
| 1 |
Ki > 4379 nM
|
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CP0198121
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(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-(4-fluorophenyl)methanone
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C21H17F3N2O2
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1
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| 1 |
Ki > 4379 nM
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CP0552031
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US9029364, 11
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C19H20N6O2S
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1
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| 1 |
Ki > 4654 nM
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CP0400936
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(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-(1H-imidazo[4,5-b]pyridin-7-yl)methanone
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C21H17F2N5O2
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1
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| 1 |
Ki > 5868 nM
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