Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(5-chloropyridin-3-yl)-N-(5,6-dimethoxypyridin-2-yl)-2-pyridin-2-ylpyridine-3-carboxamide
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 PubChem ID
CID: 134136264
Canonical SMILES
COc1ccc(NC(=O)c2cc(cnc2-c2ccccn2)-c2cncc(Cl)c2)nc1OC
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Compound Formula C23H18ClN5O3
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 18 nM
   TI
   LI
   LO
   TS