Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[4,4-difluoro-3-[5-(trifluoromethyl)pyridin-2-yl]oxypiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
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 PubChem ID
CID: 90286502
Canonical SMILES
FC(F)(F)c1ccc(OC2CN(CCC2(F)F)C(=O)c2ccccc2-n2nccn2)nc1
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Compound Formula C20H16F5N5O2
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 467 nM
   TI
   LI
   LO
   TS