Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4-chlorophenyl)-[(3R,5S)-7-(difluoromethoxy)-3,5-dimethyl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methanone
    Show/Hide
 PubChem ID
CID: 54751924
SID: 131477926
Canonical SMILES
C[C@@H]1COc2ccc(OC(F)F)cc2[C@H](C)N1C(=O)c1ccc(Cl)cc1
    Show/Hide
Compound Formula C19H18ClF2NO3
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 27 nM
   TI
   LI
   LO
   TS