Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-ethyl-1-[(1R)-1-[3-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)phenyl]ethyl]-3-[[(3S)-5-oxomorpholin-3-yl]methyl]urea
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Canonical SMILES
CCN([C@H](C)c1cccc(c1)-c1cn2ccnc2c(OC)n1)C(=O)NC[C@H]1COCC(=O)N1
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Compound Formula C23H28N6O4
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 192.9 nM
   TI
   LI
   LO
   TS