Brief Information of the Compound and Protein
Compound Name
[4,4-difluoro-3-(1,8-naphthyridin-2-yloxy)piperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
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PubChem ID
CID: 134151486
Canonical SMILES
FC1(F)CCN(CC1Oc1ccc2cccnc2n1)C(=O)c1ccccc1-n1nccn1
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Compound Formula C22H18F2N6O2
Compound Structure
Protein Name
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1407 nM
   TI
   LI
   LO
   TS