Brief Information of the Compound and Protein
Compound Name
1-ethyl-3-[(2S)-1,1,1,5,5,5-hexafluoropentan-2-yl]-1-[(1R)-1-(3-imidazo[1,2-a]pyridin-6-ylphenyl)ethyl]urea
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Canonical SMILES
CCN([C@H](C)c1cccc(c1)-c1ccc2nccn2c1)C(=O)N[C@@H](CCC(F)(F)F)C(F)(F)F
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Compound Formula C23H24F6N4O
Compound Structure
Protein Name
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 7.1 nM
   TI
   LI
   LO
   TS