Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2,6-difluoro-3-methoxyphenyl)-[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]methanone
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 PubChem ID
CID: 77107592
Canonical SMILES
COc1ccc(F)c(C(=O)N2CCC(F)(F)[C@H](C2)Oc2ccc3ccccc3n2)c1F
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Compound Formula C22H18F4N2O3
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 1227 nM
   TI
   LI
   LO
   TS