Brief Information of the Compound and Protein
Compound Name
(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-(2-methylphenyl)methanone
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PubChem ID
CID: 77105013
Canonical SMILES
Cc1ccccc1C(=O)N1CCC(F)(F)C(C1)Oc1ccc2ccccc2n1
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Compound Formula C22H20F2N2O2
Compound Structure
Protein Name
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 2633 nM
   TI
   LI
   LO
   TS