Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,2S)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-2-(3-fluoro-4-methoxyphenyl)-N-(5-fluoropyridin-2-yl)cyclopropane-1-carboxamide
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 PubChem ID
CID: 56943752
SID: 135646067
Canonical SMILES
COc1ccc(cc1F)[C@]1(COc2cnc(C)nc2C)C[C@H]1C(=O)Nc1ccc(F)cn1
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Compound Formula C23H22F2N4O3
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 7 nM
   TI
   LI
   LO
   TS