Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9029364, 7
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 PubChem ID
CID: 71526231
SID: 163519413
Canonical SMILES
C[C@@H]1CS[C@@H](COc2ccc(cn2)C(F)(F)F)CN1C(=O)c1ccccc1-n1nccn1
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Compound Formula C21H20F3N5O2S
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 66 nM
   TI
   LI
   LO
   TS