Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(2S)-5-fluoro-2-[[[5-(trifluoromethyl)pyridin-2-yl]amino]methyl]piperidin-1-yl]-(2-methyl-5-phenyl-1,3-thiazol-4-yl)methanone
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 PubChem ID
CID: 70685892
Canonical SMILES
Cc1nc(C(=O)N2CC(F)CC[C@H]2CNc2ccc(cn2)C(F)(F)F)c(s1)-c1ccccc1
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Compound Formula C23H22F4N4OS
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS