Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl)-(1H-imidazo[4,5-b]pyridin-7-yl)methanone
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 PubChem ID
CID: 134132166
Canonical SMILES
FC1(F)CCN(CC1Oc1ccc2ccccc2n1)C(=O)c1ccnc2[nH]cnc12
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Compound Formula C21H17F2N5O2
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki > 5868 nM
   TI
   LI
   LO
   TS