Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-ethyl-1-[(1S)-2,2,2-trifluoro-1-[5-methoxy-4-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)pyridin-2-yl]ethyl]-3-[1-(trifluoromethyl)cyclobutyl]urea
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Canonical SMILES
CCN([C@@H](c1cc(c(OC)cn1)-c1cn2ccnc2c(OC)n1)C(F)(F)F)C(=O)NC1(CCC1)C(F)(F)F
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Compound Formula C23H24F6N6O3
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 45.8 nM
   TI
   LI
   LO
   TS