Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[(1R)-1-(4,4-difluorooxan-2-yl)propyl]-1-ethyl-1-[(1R)-1-[3-(8-methoxyimidazo[1,2-a]pyrazin-6-yl)phenyl]ethyl]urea
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Canonical SMILES
CC[C@@H](NC(=O)N(CC)[C@H](C)c1cccc(c1)-c1cn2ccnc2c(OC)n1)C1CC(F)(F)CCO1
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Compound Formula C26H33F2N5O3
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 0.8 nM
   TI
   LI
   LO
   TS