Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(3,4-dimethoxyphenyl)sulfonyl-6-fluoro-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
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 PubChem ID
CID: 57403244
Canonical SMILES
COc1ccc(cc1OC)S(=O)(=O)N1CCOC11CCN(CC1F)C(=O)Nc1ccccc1
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Compound Formula C22H26FN3O6S
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3.3 nM
   TI
   LI
   LO
   TS