Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,2S)-N-(5-cyanopyridin-2-yl)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-2-(3-fluorophenyl)cyclopropane-1-carboxamide
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 PubChem ID
CID: 56944244
SID: 135646540
Canonical SMILES
Cc1ncc(OC[C@]2(C[C@H]2C(=O)Nc2ccc(cn2)C#N)c2cccc(F)c2)c(C)n1
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Compound Formula C23H20FN5O2
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 5 nM
   TI
   LI
   LO
   TS