Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-(2-(3,4-dichlorobenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
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 PubChem ID
CID: 127038818
Canonical SMILES
Cc1cccc(-c2sc(C)nc2C(=O)N2CCC[C@H]2Cc2ccc(Cl)c(Cl)c2)c1
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Compound Formula C23H22Cl2N2OS
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 66 nM
   TI
   LI
   LO
   TS