INCB-018424

BDBM50249542

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

3-[4-(4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)piperidin-1-yl]propanenitrile

3-(1-benzylpiperidin-4-yl)-4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene

6-(1H-indazol-6-yl)-N-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyrazin-8-amine

3-cyclohexyl-4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene

(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)methanol

(1R,3S)-3-(4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)cyclopentan-1-ol

3-[(3R,4R)-3-fluoropiperidin-4-yl]-4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene

(1R,3R)-3-(4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)cyclopentan-1-ol

(1R,3S)-3-(4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)cyclohexan-1-ol

2-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)ethanol

(1S)-1-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)ethane-1,2-diol

(1R,3R)-3-(4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)cyclohexan-1-ol

3-[[4-(4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)cyclohexyl]amino]propanenitrile

CHEMBL2159208

(1R)-1-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)ethanol

4-(4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)cyclohexan-1-ol

3-(3,3-difluoropiperidin-4-yl)-4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene

4-methyl-3-[(3S)-oxan-3-yl]-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene

4-(4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)cyclohexan-1-ol

N-[4-(4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)cyclohexyl]methanesulfonamide

(1R)-1-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)propan-1-ol

2-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)propan-2-ol

(1R)-1-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)ethane-1,2-diol

(1S)-1-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)ethanol

3-[(3S,4R)-3-fluoropiperidin-4-yl]-4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene

CHEMBL2159207

(1S)-1-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)propan-1-ol

4-methyl-3-(oxan-4-yl)-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene

4-methyl-3-piperidin-4-yl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene

3-piperidin-4-yl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene

5-amino-N-[3-(2,5-dichlorophenyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

5-amino-N-[3-(5-chloro-2-methylphenyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-[4-[4-[[5-chloro-7-[2-[methyl(methylsulfonyl)amino]phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

2-[4-[4-[[7-[2-[methyl(methylsulfonyl)amino]phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

N-[3-(5-chloro-2-methoxyphenyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-[4-[4-[[7-[3-(hydroxymethyl)phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

2-[4-[4-[[7-(4-methylsulfonylphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

N-[3-(5-chloro-2-methylphenyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-[4-[4-[[7-[2-[methyl(methylsulfonyl)amino]pyridin-3-yl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

2-[4-[4-[[5-methyl-7-[2-[methyl(methylsulfonyl)amino]phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

5-amino-N-[3-(2,5-dimethylphenyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-[4-[4-[[7-(2-methoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

N-[3-(2,5-dichlorophenyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-[4-[4-[[7-[3-[methyl(methylsulfonyl)amino]phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

N-[3-(1-methylpiperidin-4-yl)phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

2-[4-[4-[[7-(3-methylsulfonylphenyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

2-[4-[4-[[7-[3-(methanesulfonamido)phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

8-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

N-[3-(4-methylpiperazin-1-yl)phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

2-[4-[4-[[7-(6-methoxypyridin-3-yl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

N-[4-(4-methylpiperazin-1-yl)phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

N-[3-(2,5-dimethylphenyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

5-amino-N-[1-methyl-3-(2-methylphenyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

(R)-3-(6-(1-(4-fluorophenyl)butylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

N-[3-(4-methylpiperazin-1-yl)phenyl]-8-(4-propan-2-ylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

8-(4-methylsulfonylphenyl)-N-[3-(4-morpholin-4-ylpiperidin-1-yl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine

2-[4-[4-[[7-[3-(tert-butylsulfamoyl)phenyl]pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

N-[3-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

8-(4-methylsulfonylphenyl)-N-(3-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

N,8-bis(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

2-fluoro-4-{8,12,14,16-tetraazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,10,13,15-heptaen-9-yl}phenol

4-[4-(2,2-dimethylpropanoylamino)phenyl]-7-methyl-N-(3-morpholin-4-ylpropyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

3-[2-[5-methyl-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile

3-[2-[5-methyl-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile

3-chloro-4-{8,12,14,16-tetraazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,8,10,13,15-octaen-9-yl}phenol

(R)-3-(6-(1-(4-fluorophenyl)ethylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

2-[4-[4-[(7-quinolin-8-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)amino]phenyl]piperidin-1-yl]acetamide

N-(3-methoxyphenyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

N-[3-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

3-fluoro-4-{8,12,14,16-tetraazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,10,13,15-heptaen-9-yl}phenol

N-(4-methoxyphenyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

N-[3-(2,6-dichlorophenyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

4-[4-(3,8,10-triazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)pyrazol-1-yl]butanenitrile

(R)-3-(6-(1-(4-fluorophenyl)propylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

tert-butyl (2S)-2-[[4-[7-methyl-6-(3-morpholin-4-ylpropylcarbamoyl)pyrrolo[2,3-d]pyrimidin-4-yl]phenyl]carbamoyl]pyrrolidine-1-carboxylate

2-[4-[4-[(7-pyrazin-2-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)amino]phenyl]piperidin-1-yl]acetamide

4-[4-(2,2-dimethylpropanoylamino)phenyl]-7-methyl-N-(2-pyrrolidin-1-ylethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

3-[4-(4-thiophen-2-yl-3,8,10-triazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)pyrazol-1-yl]propanenitrile

8-(4-dimethylphosphorylphenyl)-N-[3-(4-methylpiperazin-1-yl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine

4-[4-[4-(5-methylthiophen-2-yl)-3,8,10-triazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl]pyrazol-1-yl]butanenitrile

N-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

8-(4-methylsulfonylphenyl)-N-phenyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine

4-[4-[4-(5-methylfuran-2-yl)-3,8,10-triazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl]pyrazol-1-yl]butanenitrile

N-(3,5-difluoro-4-morpholin-4-ylphenyl)-5-methyl-4-(5-methylsulfonyl-6,7-dihydro-4H-furo[3,2-c]pyridin-2-yl)pyrimidin-2-amine

5-methyl-4-(5-methylsulfonyl-6,7-dihydro-4H-furo[3,2-c]pyridin-2-yl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine

(R)-3-(6-(1-(4-fluorophenyl)-2-methylpropylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

BARICITINIB

N-[3-(4-methylpiperazin-1-yl)phenyl]-8-[4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine

N-(3-methylsulfonylphenyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

4-[4-(4-cyclobutyl-3,8,10-triazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)pyrazol-1-yl]butanenitrile

tert-butyl (2S)-2-[[4-[7-methyl-6-(2-pyrrolidin-1-ylethylcarbamoyl)pyrrolo[2,3-d]pyrimidin-4-yl]phenyl]carbamoyl]pyrrolidine-1-carboxylate

3-[2-[2-(3,5-difluoro-4-morpholin-4-ylanilino)-5-methylpyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile

2-[1-ethylsulfonyl-3-[4-(4-thiophen-2-yl-3,8,10-triazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile

3-fluoro-4-{8,12,14-triazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,10,13,15-heptaen-9-yl}phenol

4-((cis-1-(4-Chlorobenzyl)-2-methylpiperidin-4-yl)amino)-N-methyl-1H-pyrrolo[2,3-b]pyridine-5-carboxamide

2-fluoro-4-{8,12,14-triazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,10,13,15-heptaen-9-yl}phenol

1-(6-(2-aminopyrazolo[1,5-a]pyrimidin-3-yl)pyrimidin-4-yl)-N-ethyl-N-(3,3,3-trifluoropropyl)piperidine-3-carboxamide

4-[4-(2,2-dimethylpropanoylamino)phenyl]-7-methylpyrrolo[2,3-d]pyrimidine-6-carboxamide

2-[5-methyl-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1-benzofuran-5-carbonitrile

8-(3-methylsulfonylphenyl)-N-phenyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine

(4-{8,12,14-triazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,10,13,15-heptaen-9-yl}phenyl)methanol

4-{8,12,14-triazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,10,13,15-heptaen-9-yl}phenol

1-(6-(2-aminopyrazolo[1,5-a]pyrimidin-3-yl)pyrimidin-4-yl)-N-propyl-N-(2,2,2-trifluoroethyl)piperidine-3-carboxamide

2-[4-[4-[[7-(3-methoxypyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide

tert-butyl (2S)-2-[[4-(6-carbamoyl-7-methylpyrrolo[2,3-d]pyrimidin-4-yl)phenyl]carbamoyl]pyrrolidine-1-carboxylate

1-(6-(2-aminopyrazolo[1,5-a]pyrimidin-3-yl)pyrimidin-4-yl)-N-ethyl-N-(2,2,2-trifluoroethyl)piperidine-3-carboxamide

tert-butyl N-[(2S)-1-[4-[7-methyl-6-(2-pyrrolidin-1-ylethylcarbamoyl)pyrrolo[2,3-d]pyrimidin-4-yl]anilino]-1-oxopropan-2-yl]carbamate

ABROCITINIB

3-(6-(4-chlorobenzylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

1-(6-(2-aminopyrazolo[1,5-a]pyrimidin-3-yl)pyrimidin-4-yl)-N,N-dipropylpiperidine-3-carboxamide

5-methyl-4-(5-methylsulfonyl-6,7-dihydro-4H-furo[3,2-c]pyridin-2-yl)-N-phenylpyrimidin-2-amine

3-[2-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile

rac-3-Methyl-4-[trans-4-[2-oxo-2-(3-phenylpyrrolidin-1-yl)-ethyl]cyclohexyl]-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

[(1R,2R,4R,5S)-5-(3-Methyl-6-oxo-1,2,7-triaza-2,7-dihydroinden-4-yl)-2-norbornanyl]acetonitrile

7-methyl-4-[4-(propanoylamino)phenyl]-N-(2-pyrrolidin-1-ylethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

3-(6-(4-fluorobenzylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

3-[2-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile

4-[trans-4-[2-(4,4-Dimethyl-1-piperidyl)-2-oxo-ethyl]-cyclohexyl]-3-methyl-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

4-(4-acetamidophenyl)-7-methyl-N-(2-pyrrolidin-1-ylethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

4-(5-methylsulfonyl-6,7-dihydro-4H-furo[3,2-c]pyridin-2-yl)-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]pyrimidin-2-amine

(R)-3-(6-(1-phenylethylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

tert-butyl N-[(2S)-1-[4-(6-carbamoyl-7-methylpyrrolo[2,3-d]pyrimidin-4-yl)anilino]-1-oxopropan-2-yl]carbamate

2-bromo-4-{8,12,14-triazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,10,13,15-heptaen-9-yl}phenol

4-[trans-4-[2-(3-Benzylazetidin-1-yl)-2-oxo-ethyl]-cyclohexyl]-3-methyl-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

3-chloro-4-{8,12,14-triazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,10,13,15-heptaen-9-yl}phenol

1-(6-(2-aminopyrazolo[1,5-a]pyrimidin-3-yl)pyrimidin-4-yl)-N-ethyl-N-propylpiperidine-3-carboxamide

(R)-3-(6-(1-(4-chlorophenyl)ethylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

rac-3-Methyl-4-[(1S*,2R*)-2-methylcyclohexyl]-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

rac-4-(2-Bicyclo[2.2.2]octanyl)-3-methyl-2,7-dihydropyrazolo-[3,4-b]pyridin-6-one

tert-butyl N-[(2S)-1-[4-[7-methyl-6-(3-morpholin-4-ylpropylcarbamoyl)pyrrolo[2,3-d]pyrimidin-4-yl]anilino]-1-oxopropan-2-yl]carbamate

4-(4-acetamidophenyl)-7-methyl-N-(3-morpholin-4-ylpropyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

1-Cyclobutyl-N-[trans-4-(3-methyl-6-oxo-2,7-dihydropyrazolo[3,4-b]pyridin-4-yl)cyclohexyl]-methanesulfonamide

2-[1-ethylsulfonyl-3-[4-[4-[5-(hydroxymethyl)furan-2-yl]-3,8,10-triazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl]pyrazol-1-yl]azetidin-3-yl]acetonitrile

3-[trans-4-(3-Methyl-6-oxo-2,7-dihydropyrazolo[3,4-b]-pyridin-4-yl)cyclohexyl]propanenitrile

N-[trans-4-(3-Methyl-6-oxo-2,7-dihydropyrazolo[3,4-b]-pyridin-4-yl)cyclohexyl]cyclopropanecarboxamide

[(1S,2S,4S,5R)-5-(3-Methyl-6-oxo-1,2,7-triaza-2,7-dihydroinden-4-yl)-2-norbornanyl]acetonitrile

7-methyl-4-[4-(propanoylamino)phenyl]pyrrolo[2,3-d]pyrimidine-6-carboxamide

4-[4-[(4-cyanobenzoyl)amino]phenyl]-7-methyl-N-(2-pyrrolidin-1-ylethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

(S)-3-(6-(1-phenylethylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

(R)-3-(6-(2,3-dihydro-1H-inden-1-ylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

(4-{8,12,14-triazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,10,13,15-heptaen-9-yl}phenyl)boronic acid

3-(6-(4-fluorobenzyloxy)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

3-(6-(pyridin-2-ylmethylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

3-(6-(benzylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

3-(6-(2-(4-fluorophenyl)pyrrolidin-1-yl)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine

1-(6-(2-aminopyrazolo[1,5-a]pyrimidin-3-yl)pyrimidin-4-yl)-N,N-diethylpiperidine-3-carboxamide hydrochloride

benzyl 7-methyl-4-[4-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]phenyl]pyrrolo[2,3-d]pyrimidine-6-carboxylate

4-[4-[(4-cyanobenzoyl)amino]phenyl]-7-methyl-N-(3-morpholin-4-ylpropyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

4-(4-acetamidophenyl)-7-methylpyrrolo[2,3-d]pyrimidine-6-carboxamide

4-(4-benzamidophenyl)-7-methylpyrrolo[2,3-d]pyrimidine-6-carboxamide

benzyl 7-methyl-4-[4-[[(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carbonyl]amino]phenyl]pyrrolo[2,3-d]pyrimidine-6-carboxylate

7-methyl-N-(3-morpholin-4-ylpropyl)-4-[4-(propanoylamino)phenyl]pyrrolo[2,3-d]pyrimidine-6-carboxamide

rac-3-Methyl-4-[(1R*,2S*,4S*)-norbornan-2-yl]-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

[(1S,2R,4S,5R)-5-(3-Methyl-6-oxo-1,2,7-triaza-2,7-dihydroinden-4-yl)-2-norbornanyl]acetonitrile

[trans-4-(3-Methyl-6-oxo-2,7-dihydropyrazolo[3,4-b]-pyridin-4-yl)cyclohexyl] (1S)-2,2-difluorocyclopropanecarboxylate

1-[2-[trans-4-(3-Methyl-6-oxo-2,7-dihydropyrazolo[3,4-b]-pyridin-4-yl)cyclohexyl]acetyl]azetidine-3-carbonitrile

N-[trans-4-(3-Methyl-6-oxo-2,7-dihydropyrazolo[3,4-b]-pyridin-4-yl)cyclohexyl]cyclopentanecarboxamide

4-(cyclobutylmethyl)-3-methyl-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

4-cyclohexyl-3-cyclopropyl-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

4-cyclohexyl-5-(hydroxymethyl)-3-methyl-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

4-cyclopentyl-3-methyl-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

4-cyclohexyl-3-ethyl-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

4-cyclohexyl-3-methyl-6-oxo-2,7-dihydropyrazolo[3,4-b]pyridine-5-carbonitrile

4-cyclohexyl-3-methyl-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

4-cyclohexyl-5-(2-hydroxyethyl)-3-methyl-2,7-dihydropyrazolo[3,4-b]pyridin-6-one

2-[trans-4-(3-Methyl-6-oxo-2,7-dihydropyrazolo[3,4-b]-pyridin-4-yl)cyclohexyl]acetonitrile

4-(4-trans-Aminocyclohexyl)-3-methyl-2,7-dihydropyrazolo[3,4-b]pyridin-6-one