Brief Information of the Compound and Protein
Compound Name
2-[4-[4-[[7-(2,2-difluoro-1,3-benzodioxol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]amino]phenyl]piperidin-1-yl]acetamide
    Show/Hide
PubChem ID
CID: 46852812
SID: 99241895
Canonical SMILES
NC(=O)CN1CCC(CC1)c1ccc(Nc2ncc3ccc(-c4cccc5OC(F)(F)Oc45)n3n2)cc1
    Show/Hide
Compound Formula C26H24F2N6O3
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS