Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-(4-methylpiperazin-1-yl)phenyl]-8-(4-propan-2-ylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine
    Show/Hide
 PubChem ID
CID: 49838775
SID: 104165245
Canonical SMILES
CC(C)S(=O)(=O)c1ccc(cc1)-c1cccn2nc(Nc3cccc(c3)N3CCN(C)CC3)nc12
    Show/Hide
Compound Formula C26H30N6O2S
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 85 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.3 nM