Brief Information of the Compound and Protein
Compound Name
3-(6-(2-(4-fluorophenyl)pyrrolidin-1-yl)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine
    Show/Hide
PubChem ID
CID: 44158658
SID: 85158759
Canonical SMILES
Nc1nn2cccnc2c1-c1cc(ncn1)N1CCCC1c1ccc(F)cc1
    Show/Hide
Compound Formula C20H18FN7
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.4 nM