Brief Information of the Compound and Protein
Compound Name
N-[3-(5-chloro-2-methoxyphenyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
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PubChem ID
CID: 49856845
SID: 104229963
Canonical SMILES
COc1ccc(Cl)cc1-c1nn(C)cc1NC(=O)c1cnn2cccnc12
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Compound Formula C18H15ClN6O2
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 = 22.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.3 nM