Brief Information of the Compound and Protein
Compound Name
N,8-bis(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine
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PubChem ID
CID: 57514092
SID: 144086254
Canonical SMILES
CS(=O)(=O)c1ccc(Nc2nc3c(cccn3n2)-c2ccc(cc2)S(C)(=O)=O)cc1
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Compound Formula C20H18N4O4S2
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 = 118 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.3 nM