Brief Information of the Compound and Protein
Compound Name
5-methyl-4-(5-methylsulfonyl-6,7-dihydro-4H-furo[3,2-c]pyridin-2-yl)-N-phenylpyrimidin-2-amine
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PubChem ID
CID: 72201823
Canonical SMILES
Cc1cnc(Nc2ccccc2)nc1-c1cc2CN(CCc2o1)S(C)(=O)=O
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Compound Formula C19H20N4O3S
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000082 HEL Homo sapiens (Human)  1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 = 2222 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.7 nM