Brief Information of the Compound and Protein
Compound Name
4-cyclohexyl-3-methyl-6-oxo-2,7-dihydropyrazolo[3,4-b]pyridine-5-carbonitrile
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PubChem ID
CID: 156009831
Canonical SMILES
Cc1[nH]nc2[nH]c(=O)c(C#N)c(C3CCCCC3)c12
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Compound Formula C14H16N4O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 > 40000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 17000 nM