Brief Information of the Compound and Protein
Compound Name
 Compound Info 
rac-3-Methyl-4-[(1S*,2R*)-2-methylcyclohexyl]-2,7-dihydropyrazolo[3,4-b]pyridin-6-one
    Show/Hide
 PubChem ID
CID: 156015109
Canonical SMILES
Cc1[nH]nc2[nH]c(=O)cc([C@H]3CCCC[C@H]3C)c12
    Show/Hide
Compound Formula C14H19N3O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 8900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 340 nM