Brief Information of the Compound and Protein
Compound Name
3-chloro-4-{8,12,14,16-tetraazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,8,10,13,15-octaen-9-yl}phenol
    Show/Hide
PubChem ID
CID: 135971388
Canonical SMILES
Oc1ccc(c(Cl)c1)-c1nc2ccccc2c2ncnc3[nH]cc1c23
    Show/Hide
Compound Formula C19H11ClN4O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.8 nM