Brief Information of the Compound and Protein
Compound Name
2-[4-[4-[(7-quinolin-8-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)amino]phenyl]piperidin-1-yl]acetamide
    Show/Hide
PubChem ID
CID: 57392677
Canonical SMILES
NC(=O)CN1CCC(CC1)c1ccc(Nc2ncc3ccc(-c4cccc5cccnc45)n3n2)cc1
    Show/Hide
Compound Formula C28H27N7O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS