Brief Information of the Compound and Protein
Compound Name
3-fluoro-4-{8,12,14-triazatetracyclo[8.6.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,10,13,15-heptaen-9-yl}phenol
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PubChem ID
CID: 46224797
Canonical SMILES
Oc1ccc(C2Nc3ccccc3-c3ccnc4[nH]cc2c34)c(F)c1
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Compound Formula C20H14FN3O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 = 720 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.6 nM