Brief Information of the Compound and Protein
Compound Name
2-[1-ethylsulfonyl-3-[4-(4-thiophen-2-yl-3,8,10-triazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile
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Canonical SMILES
CCS(=O)(=O)N1CC(CC#N)(C1)n1cc(cn1)-n1c(cc2cnc3[nH]ccc3c12)-c1cccs1
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Compound Formula C23H21N7O2S2
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 = 696 nM
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