Brief Information of the Compound and Protein
Compound Name
5-amino-N-[1-methyl-3-(2-methylphenyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    Show/Hide
PubChem ID
CID: 58063146
SID: 163503192
Canonical SMILES
Cc1ccccc1-c1nn(C)cc1NC(=O)c1cnn2ccc(N)nc12
    Show/Hide
Compound Formula C18H17N7O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 = 68.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.6 nM