Brief Information of the Compound and Protein
Compound Name
3-(6-(4-chlorobenzylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine
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PubChem ID
CID: 44159711
SID: 85159849
Canonical SMILES
Nc1nn2cccnc2c1-c1cc(NCc2ccc(Cl)cc2)ncn1
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Compound Formula C17H14ClN7
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.4 nM